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1ABO
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE ABL TYROSINE KINASE SH3 DOMAIN WITH 3BP-1 SYNTHETIC PEPTIDE
分子名称:ABL TYROSINE KINASE, 3BP-1 SYNTHETIC PEPTIDE, 10 RESIDUES, ...
著者Musacchio, A., Wilmanns, M., Saraste, M.
登録日1995-05-19
公開日1995-10-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides.
Nat.Struct.Biol., 1, 1994
1ABQ
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CRYSTAL STRUCTURE OF THE UNLIGANDED ABL TYROSINE KINASE SH3 DOMAIN
分子名称:ABL TYROSINE KINASE SRC-HOMOLOGY 3 (SH3) DOMAIN
著者Musacchio, A., Wilmanns, M., Saraste, M.
登録日1995-05-19
公開日1995-10-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides.
Nat.Struct.Biol., 1, 1994
1PBW
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STRUCTURE OF BCR-HOMOLOGY (BH) DOMAIN
分子名称:PHOSPHATIDYLINOSITOL 3-KINASE
著者Musacchio, A., Cantley, L.C., Harrison, S.C.
登録日1996-10-17
公開日1997-03-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunit.
Proc.Natl.Acad.Sci.USA, 93, 1996
1FYN
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PHOSPHOTRANSFERASE
分子名称:PHOSPHOTRANSFERASE FYN, 3BP-2
著者Musacchio, A., Saraste, M., Wilmanns, M.
登録日1995-05-17
公開日1996-11-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides.
Nat.Struct.Biol., 1, 1994
1SHG
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CRYSTAL STRUCTURE OF A SRC-HOMOLOGY 3 (SH3) DOMAIN
分子名称:ALPHA-SPECTRIN SH3 DOMAIN
著者Noble, M., Pauptit, R., Musacchio, A., Saraste, M., Wierenga, R.K.
登録日1993-05-19
公開日1993-10-31
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a Src-homology 3 (SH3) domain.
Nature, 359, 1992
2WB8
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CRYSTAL STRUCTURE OF HASPIN KINASE
分子名称:SERINE/THREONINE-PROTEIN KINASE HASPIN
著者Villa, F., Tortorci, M., Forneris, F., Mattevi, A., Musacchio, A.
登録日2009-02-23
公開日2009-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structure of the Catalytic Domain of Haspin, an Atypical Kinase Implicated in Chromatin Organization.
Proc.Natl.Acad.Sci.USA, 106, 2009
3IF8
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CRYSTAL STRUCTURE OF ZWILCH, A MEMBER OF THE RZZ KINETOCHORE COMPLEX
分子名称:Protein zwilch homolog
著者Wehenkel, A., Civril, F., Musacchio, A.
登録日2009-07-24
公開日2010-06-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery.
Structure, 18, 2010
4NF9
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STRUCTURE OF THE KNL1/NSL1 COMPLEX
分子名称:Protein CASC5, Kinetochore-associated protein NSL1 homolog, CHLORIDE ION
著者Petrovic, A., Mosalaganti, S., Keller, J., Mattiuzzo, M., Overlack, K., Wohlgemuth, S., Pasqualato, S., Raunser, S., Musacchio, A.
登録日2013-10-31
公開日2014-03-19
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization.
Mol.Cell, 53, 2014
4NFA
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STRUCTURE OF THE C-TERMINAL DOAMIN OF KNL1
分子名称:Protein CASC5, CHLORIDE ION, GLYCEROL
著者Petrovic, A., Mosalaganti, S., Keller, J., Mattiuzzo, M., Overlack, K., Wohlgemuth, S., Pasqualato, S., Raunser, S., Musacchio, A.
登録日2013-10-31
公開日2014-03-19
実験手法X-RAY DIFFRACTION (2.497 Å)
主引用文献Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization.
Mol.Cell, 53, 2014
1GO4
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CRYSTAL STRUCTURE OF MAD1-MAD2 REVEALS A CONSERVED MAD2 BINDING MOTIF IN MAD1 AND CDC20.
分子名称:Mitotic spindle assembly checkpoint protein MAD2A, Mitotic spindle assembly checkpoint protein MAD1
著者Sironi, L., Mapelli, M., Jeang, K.T., Musacchio, A.
登録日2001-10-17
公開日2002-05-16
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint.
EMBO J., 21, 2002
2V66
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CRYSTAL STRUCTURE OF THE COILED-COIL DOMAIN OF NDEL1 (A.A. 58 TO 169) C
分子名称:NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1, MERCURY (II) ION
著者Tarricone, C., Perrina, F., Musacchio, A.
登録日2007-07-13
公開日2007-11-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Structure of the Coiled-Coil Domain of Ndel1 and the Basis of its Interaction with Lis1, the Causal Protein of Miller-Dieker Lissencephaly.
Structure, 15, 2007
2VE7
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CRYSTAL STRUCTURE OF A BONSAI VERSION OF THE HUMAN NDC80 COMPLEX
分子名称:KINETOCHORE PROTEIN HEC1, KINETOCHORE PROTEIN SPC25, KINETOCHORE PROTEIN NUF2, ...
著者Ciferri, C., Pasqualato, S., Dos Reis, G., Screpanti, E., Maiolica, A., Polka, J., De Luca, J.G., De Wulf, P., Salek, M., Rappsilber, J., Moores, C.A., Salmon, E.D., Musacchio, A.
登録日2007-10-17
公開日2008-05-13
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex
Cell(Cambridge,Mass.), 133, 2008
2XBB
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NEDD4 HECT:UB COMPLEX
分子名称:E3 UBIQUITIN-PROTEIN LIGASE NEDD4, UBIQUITIN, GLYCEROL
著者Maspero, E., Cecatiello, V., Musacchio, A., Polo, S., Pasqualato, S.
登録日2010-04-08
公開日2011-03-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Structure of the Hect:Ubiquitin Complex and its Role in Ubiquitin Chain Elongation
Embo Rep., 12, 2011
2XBF
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NEDD4 HECT STRUCTURE
分子名称:E3 UBIQUITIN-PROTEIN LIGASE NEDD4, 1,2-ETHANEDIOL, CALCIUM ION
著者Maspero, E., Cecatiello, V., Musacchio, A., Polo, S., Pasqualato, S.
登録日2010-04-09
公開日2011-03-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Structure of the Hect:Ubiquitin Complex and its Role in Ubiquitin Chain Elongation
Embo Rep., 12, 2011
4A1G
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THE CRYSTAL STRUCTURE OF THE HUMAN BUB1 TPR DOMAIN IN COMPLEX WITH THE KI MOTIF OF KNL1
分子名称:MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1, PROTEIN CASC5
著者Krenn, V., Wehenkel, A., Li, X., Santaguida, S., Musacchio, A.
登録日2011-09-15
公開日2012-02-29
最終更新日2017-08-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Analysis Reveals Features of the Spindle Checkpoint Kinase Bub1-Kinetochore Subunit Knl1 Interaction.
J.Cell Biol., 196, 2012
4BL0
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CRYSTAL STRUCTURE OF YEAST BUB3-BUB1 BOUND TO PHOSPHO-SPC105
分子名称:CELL CYCLE ARREST PROTEIN BUB3, CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1, SPINDLE POLE BODY COMPONENT SPC105, ...
著者Primorac, I., Weir, J.R., Musacchio, A.
登録日2013-04-30
公開日2013-09-18
最終更新日2013-10-09
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Bub3 Reads Phosphorylated Melt Repeats to Promote Spindle Assembly Checkpoint Signaling
Elife, 2, 2013
4P0T
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CRYSTAL STRUCTURE OF HUMAN CENTROMERE PROTEIN M
分子名称:Centromere protein M, GLYCEROL
著者Basilico, F., Pasqualato, S., Musacchio, A.
登録日2014-02-22
公開日2014-07-09
最終更新日2014-07-23
実験手法X-RAY DIFFRACTION (1.493 Å)
主引用文献The pseudo GTPase CENP-M drives human kinetochore assembly.
Elife, 3, 2014
5DMZ
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STRUCTURE OF HUMAN BUB1 KINASE DOMAIN PHOSPHORYLATED AT SER969
分子名称:Mitotic checkpoint serine/threonine-protein kinase BUB1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Breit, C., Weir, J.R., Musacchio, A.
登録日2015-09-09
公開日2015-12-16
最終更新日2016-10-19
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1.
Plos One, 10, 2015
6C0W
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CRYO-EM STRUCTURE OF HUMAN KINETOCHORE PROTEIN CENP-N WITH THE CENTROMERIC NUCLEOSOME CONTAINING CENP-A
分子名称:Histone H3-like centromeric protein A, Histone H4, Histone H2A, ...
著者Zhou, K., Pentakota, S., Vetter, I.R., Morgan, G.P., Petrovic, A., Musacchio, A., Luger, K.
登録日2018-01-02
公開日2018-01-17
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Decoding the centromeric nucleosome through CENP-N.
Elife, 6, 2017
6EQT
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CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE PROTEIN CENP-N
分子名称:Centromere protein N
著者Pentakota, S., Vetter, I.R., Petrovic, A., Musacchio, A.
登録日2017-10-15
公開日2018-01-17
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.735 Å)
主引用文献Decoding the centromeric nucleosome through CENP-N.
Elife, 6, 2017
1BPO
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CLATHRIN HEAVY-CHAIN TERMINAL DOMAIN AND LINKER
分子名称:PROTEIN (CLATHRIN)
著者Harr, E.T., Musacchio, A., Harrison, S.C., Kirchhausen, T.
登録日1998-08-11
公開日1998-12-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker.
Cell(Cambridge,Mass.), 95, 1998
1H4L
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STRUCTURE AND REGULATION OF THE CDK5-P25(NCK5A) COMPLEX
分子名称:CELL DIVISION PROTEIN KINASE 5, CYCLIN-DEPENDENT KINASE 5 ACTIVATOR
著者Tarricone, C., Dhavan, R., Peng, J., Areces, L.B., Tsai, L.-H., Musacchio, A.
登録日2001-05-11
公開日2002-08-14
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure and Regulation of the Cdk5-P25(Nck5A) Complex
Mol.Cell, 8, 2001
1RGP
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GTPASE-ACTIVATION DOMAIN FROM RHOGAP
分子名称:RHOGAP
著者Barrett, T., Xiao, B., Dodson, E.J., Dodson, G., Ludbrook, S.B., Nurmahomed, K., Gamblin, S.J., Musacchio, A., Smerdon, S.J., Eccleston, J.F.
登録日1996-12-05
公開日1997-10-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of the GTPase-activating domain from p50rhoGAP.
Nature, 385, 1997
1SHF
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CRYSTAL STRUCTURE OF THE SH3 DOMAIN IN HUMAN FYN; COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF SH3 DOMAINS IN TYROSINE KINASES AND SPECTRIN
分子名称:FYN TYROSINE KINASE SH3 DOMAIN
著者Noble, M., Musacchio, A., Saraste, M., Wierenga, R.
登録日1993-05-19
公開日1993-10-31
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the SH3 domain in human Fyn; comparison of the three-dimensional structures of SH3 domains in tyrosine kinases and spectrin.
EMBO J., 12, 1993
1UNG
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STRUCTURAL MECHANISM FOR THE INHIBITION OF CDK5-P25 BY ROSCOVITINE, ALOISINE AND INDIRUBIN.
分子名称:CELL DIVISION PROTEIN KINASE 5, CYCLIN-DEPENDENT KINASE 5 ACTIVATOR 1, 6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE
著者Mapelli, M., Crovace, C., Massimiliano, L., Musacchio, A.
登録日2003-09-10
公開日2004-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism of Cdk5/P25 Binding by Cdk Inhibitors
J.Med.Chem., 48, 2005
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