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4NTJ
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STRUCTURE OF THE HUMAN P2Y12 RECEPTOR IN COMPLEX WITH AN ANTITHROMBOTIC DRUG
Descriptor:P2Y purinoceptor 12,Soluble cytochrome b562,P2Y purinoceptor 12, ethyl 6-{4-[(benzylsulfonyl)carbamoyl]piperidin-1-yl}-5-cyano-2-methylpyridine-3-carboxylate, CHOLESTEROL, ...
Authors:Zhang, K., Zhang, J., Gao, Z.-G., Zhang, D., Zhu, L., Han, G.W., Moss, S.M., Paoletta, S., Kiselev, E., Lu, W., Fenalti, G., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR)
Deposit date:2013-12-02
Release date:2014-03-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structure of the human P2Y12 receptor in complex with an antithrombotic drug
Nature, 509, 2014
5VBE
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CRYSTAL STRUCTURE OF SMALL MOLECULE DISULFIDE 2C07 BOUND TO H-RAS M72C GDP
Descriptor:GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, 1-(4-methoxyphenyl)-N-(3-sulfanylpropyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide, ...
Authors:Gentile, D.R., Jenkins, M.L., Moss, S.M., Burke, J.E., Shokat, K.M.
Deposit date:2017-03-29
Release date:2017-10-25
Last modified:2018-01-03
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.
Cell Chem Biol, 24, 2017
5VBM
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CRYSTAL STRUCTURE OF SMALL MOLECULE DISULFIDE 2C07 BOUND TO K-RAS CYS LIGHT M72C GDP
Descriptor:GTPase KRas, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Gentile, D.R., Jenkins, M.L., Moss, S.M., Burke, J.E., Shokat, K.M.
Deposit date:2017-03-29
Release date:2017-10-25
Last modified:2018-01-03
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.
Cell Chem Biol, 24, 2017
5VBZ
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CRYSTAL STRUCTURE OF SMALL MOLECULE DISULFIDE 2C07 BOUND TO H-RAS M72C GPPNHP
Descriptor:GTPase HRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Gentile, D.R., Jenkins, M.L., Moss, S.M., Burke, J.E., Shokat, K.M.
Deposit date:2017-03-30
Release date:2017-10-25
Last modified:2018-01-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.
Cell Chem Biol, 24, 2017