Author results

3B8E
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CRYSTAL STRUCTURE OF THE SODIUM-POTASSIUM PUMP
Descriptor:Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1, Na+/K+ ATPase gamma subunit transcript variant a, ...
Authors:Morth, J.P., Pedersen, P.B., Toustrup-Jensen, M.S., Soerensen, T.L.M., Petersen, J., Andersen, J.P., Vilsen, B., Nissen, P.
Deposit date:2007-11-01
Release date:2007-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the sodium-potassium pump.
Nature, 450, 2007
3KDP
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CRYSTAL STRUCTURE OF THE SODIUM-POTASSIUM PUMP
Descriptor:Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1, Na+/K+ ATPase gamma subunit transcript variant a, ...
Authors:Morth, J.P., Pedersen, B.P., Nissen, P.
Deposit date:2009-10-23
Release date:2010-02-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the sodium-potassium pump.
Nature, 450, 2007
1S8N
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CRYSTAL STRUCTURE OF RV1626 FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:putative antiterminator, AZIDE ION
Authors:Morth, J.P., Feng, V., Perry, L.J., Svergun, D.I., Tucker, P.A., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-02-03
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.482 Å)
Cite:The Crystal and Solution Structure of a Putative Transcriptional Antiterminator from Mycobacterium tuberculosis.
Structure, 12, 2004
1SD5
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CRYSTAL STRUCTURE OF RV1626
Descriptor:putative antiterminator, IODIDE ION
Authors:Morth, J.P., Feng, V., Perry, L.J., Svergun, D.I., Tucker, P.A., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-02-13
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:The Crystal and Solution Structure of a Putative Transcriptional Antiterminator from Mycobacterium tuberculosis.
Structure, 12, 2004
3B9B
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STRUCTURE OF THE E2 BERYLLIUM FLUORIDE COMPLEX OF THE SERCA CA2+-ATPASE
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SODIUM ION, MAGNESIUM ION, ...
Authors:Olesen, C., Picard, M., Winther, A.M.L., Morth, J.P., Moller, J.V., Nissen, P.
Deposit date:2007-11-04
Release date:2007-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The structural basis of calcium transport by the calcium pump.
Nature, 450, 2007
3B9R
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SERCA CA2+-ATPASE E2 ALUMINIUM FLUORIDE COMPLEX WITHOUT THAPSIGARGIN
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, TETRAFLUOROALUMINATE ION, MAGNESIUM ION, ...
Authors:Olesen, C., Picard, M., Winther, A.M.L., Morth, J.P., Moller, J.V., Nissen, P.
Deposit date:2007-11-06
Release date:2007-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structural basis of calcium transport by the calcium pump
Nature, 450, 2007
3BA6
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STRUCTURE OF THE CA2E1P PHOSPHOENZYME INTERMEDIATE OF THE SERCA CA2+-ATPASE
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, CALCIUM ION, POTASSIUM ION, ...
Authors:Picard, M., Winther, A.M.L., Olesen, C., Gyrup, C., Morth, J.P., Oxvig, C., Moller, J.V., Nissen, P.
Deposit date:2007-11-07
Release date:2007-12-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural basis of calcium transport by the calcium pump.
Nature, 450, 2007
3FGO
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CRYSTAL STRUCTURE OF THE E2 MAGNESIUM FLUORIDE COMPLEX OF THE (SR) CA2+-ATPASE WITH BOUND CPA AND AMPPCP
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, MAGNESIUM ION, TETRAFLUOROMAGNESATE(2-), ...
Authors:Laursen, M., Bublitz, M., Moncoq, K., Olesen, C., Moller, J.V., Young, H.S., Nissen, P., Morth, J.P.
Deposit date:2008-12-08
Release date:2009-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 2009
3FPB
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THE STRUCTURE OF SARCOPLASMIC RETICULUM CA2+-ATPASE BOUND TO CYCLOPIAZONIC ACID WITH ATP
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, MAGNESIUM ION, TETRAFLUOROMAGNESATE(2-), ...
Authors:Moncoq, K., Morth, J.P., Bublitz, M., Laursen, M., Nissen, P., Young, H.S.
Deposit date:2009-01-05
Release date:2009-04-07
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 284, 2009
3FPS
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THE STRUCTURE OF SARCOPLASMIC RETICULUM CA2+-ATPASE BOUND TO CYCLOPIAZONIC AND ADP
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, MAGNESIUM ION, (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, ...
Authors:Moncoq, K., Morth, J.P., Bublitz, M., Laursen, M., Nissen, P., Young, H.S.
Deposit date:2009-01-06
Release date:2009-04-07
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 284, 2009
3JQZ
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CRYSTAL STRUCTURE OF HUMAN SERUM ALBUMIN COMPLEXED WITH LIDOCAINE
Descriptor:Serum albumin, 2-(diethylamino)-N-(2,6-dimethylphenyl)ethanamide
Authors:Hein, K.L., Kragh-Hansen, U., Morth, J.P., Nissen, P.
Deposit date:2009-09-08
Release date:2010-04-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystallographic analysis reveals a unique lidocaine binding site on human serum albumin.
J.Struct.Biol., 2010
3JRY
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HUMAN SERUM ALBUMIN WITH BOUND SULFATE
Descriptor:Serum albumin, SULFATE ION
Authors:Hein, K.L., Kragh-Hansen, U., Morth, J.P., Nissen, P.
Deposit date:2009-09-09
Release date:2010-04-21
Last modified:2013-12-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic analysis reveals a unique lidocaine binding site on human serum albumin.
J.Struct.Biol., 171, 2010
3N23
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CRYSTAL STRUCTURE OF THE HIGH AFFINITY COMPLEX BETWEEN OUABAIN AND THE E2P FORM OF THE SODIUM-POTASSIUM PUMP
Descriptor:Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1, Na+/K+ ATPase gamma subunit transcript variant a, ...
Authors:Yatime, L., Laursen, M., Morth, J.P., Esmann, M., Nissen, P., Fedosova, N.U.
Deposit date:2010-05-17
Release date:2011-01-19
Last modified:2014-09-17
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase.
J.Struct.Biol., 174, 2011
3N5K
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STRUCTURE OF THE (SR)CA2+-ATPASE E2-ALF4- FORM
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ...
Authors:Bublitz, M., Olesen, C., Poulsen, H., Morth, J.P., Moller, J.V., Nissen, P.
Deposit date:2010-05-25
Release date:2011-06-08
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 288, 2013
3N8G
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STRUCTURE OF THE (SR)CA2+-ATPASE CA2-E1-CAAMPPCP FORM
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform SERCA 1a, CALCIUM ION, POTASSIUM ION, ...
Authors:Bublitz, M., Olesen, C., Poulsen, H., Morth, J.P., Moller, J.V., Nissen, P.
Deposit date:2010-05-28
Release date:2011-06-08
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.585 Å)
Cite:Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 288, 2013
3Q02
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CRYSTAL STRUCTURE OF PLASMINOGEN ACTIVATOR INHIBITOR-1 IN A METASTABLE ACTIVE CONFORMATION.
Descriptor:Plasminogen activator inhibitor 1, CHLORIDE ION, ZINC ION, ...
Authors:Jensen, J.K., Morth, J.P.
Deposit date:2010-12-15
Release date:2011-06-22
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability.
J.Biol.Chem., 286, 2011
3Q03
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CRYSTAL STRUCTURE OF PLASMINOGEN ACTIVATOR INHIBITOR-1 IN A METASTABLE ACTIVE CONFORMATION.
Descriptor:Plasminogen activator inhibitor 1, ZINC ION, CHLORIDE ION
Authors:Jensen, J.K., Morth, J.P.
Deposit date:2010-12-15
Release date:2011-06-22
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.6401 Å)
Cite:Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability.
J.Biol.Chem., 286, 2011
3RFU
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CRYSTAL STRUCTURE OF A COPPER-TRANSPORTING PIB-TYPE ATPASE
Descriptor:Copper efflux ATPase, TETRAFLUOROALUMINATE ION, MAGNESIUM ION, ...
Authors:Gourdon, P., Liu, X., Skjorringe, T., Morth, J.P., Birk Moller, L., Panyella Pedersen, B., Nissen, P.
Deposit date:2011-04-07
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a copper-transporting PIB-type ATPase.
Nature, 475, 2011
4BYG
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ATPASE CRYSTAL STRUCTURE
Descriptor:COPPER EFFLUX ATPASE, TETRAFLUOROALUMINATE ION, MAGNESIUM ION, ...
Authors:Mattle, D., Drachmann, N.D., Liu, X.Y., Pedersen, B.P., Morth, J.P., Wang, J., Gourdon, P., Nissen, P.
Deposit date:2013-07-19
Release date:2014-08-06
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Dephosphorylation of Pib-Type Cu(I)-Atpases as Studied by Metallofluoride Complexes
To be Published
4H9G
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PROBING EF-TU WITH A VERY SMALL BROMINATED FRAGMENT LIBRARY IDENTIFIES THE CCA POCKET
Descriptor:Elongation factor Tu-A, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Groftehauge, M.K., Therkelsen, M., Taaning, R.H., Skrydstrup, T., Morth, J.P., Nissen, P.
Deposit date:2012-09-24
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Identifying ligand-binding hot spots in proteins using brominated fragments.
Acta Crystallogr.,Sect.F, 69, 2013
4HYF
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STRUCTURAL BASIS AND SAR FOR OD 270, A LEAD STAGE 1,2,4-TRIAZOLE BASED SPECIFIC TANKYRASE1/2 INHIBITOR
Descriptor:Tankyrase-2, NICOTINAMIDE, ZINC ION, ...
Authors:Perdreau, H., Ekblad, B., Voronkov, A., Holsworth, D.D., Waaler, J., Drewes, G., Schueler, H., Krauss, S., Morth, J.P.
Deposit date:2012-11-13
Release date:2013-03-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis and SAR for G007-LK, a Lead Stage 1,2,4-Triazole Based Specific Tankyrase 1/2 Inhibitor.
J.Med.Chem., 56, 2013
4J0N
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CRYSTAL STRUCTURE OF A MANGANESE DEPENDENT ISATIN HYDROLASE
Descriptor:Isatin hydrolase B, MANGANESE (II) ION, SODIUM ION, ...
Authors:Bjerregaard-Andersen, K., Sommer, T., Jensen, J.K., Jochimsen, B., Etzerodt, M., Morth, J.P.
Deposit date:2013-01-31
Release date:2013-02-20
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:A proton wire and water channel revealed in the crystal structure of isatin hydrolase.
J.Biol.Chem., 289, 2014
4LBV
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IDENTIFYING LIGAND BINDING HOT SPOTS IN PROTEINS USING BROMINATED FRAGMENTS
Descriptor:Elongation factor Tu-A, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Groftehauge, M.K., Therkelsen, M., Taaning, R., Skrydstrup, T., Morth, J.P., Nissen, P.
Deposit date:2013-06-21
Release date:2013-09-11
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Identifying ligand-binding hot spots in proteins using brominated fragments.
Acta Crystallogr.,Sect.F, 69, 2013
4LBW
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IDENTIFYING LIGAND BINDING HOT SPOTS IN PROTEINS USING BROMINATED FRAGMENTS
Descriptor:Elongation factor Tu-A, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Groftehauge, M.K., Therkelsen, M., Taaning, R., Skrydstrup, T., Morth, J.P., Nissen, P.
Deposit date:2013-06-21
Release date:2013-09-11
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.741 Å)
Cite:Identifying ligand-binding hot spots in proteins using brominated fragments.
Acta Crystallogr.,Sect.F, 69, 2013
4LBY
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IDENTIFYING LIGAND BINDING HOT SPOTS IN PROTEINS USING BROMINATED FRAGMENTS
Descriptor:Elongation factor Tu-A, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Groftehauge, M.K., Therkelsen, M., Taaning, R., Skrydstrup, T., Morth, J.P., Nissen, P.
Deposit date:2013-06-21
Release date:2013-09-11
Method:X-RAY DIFFRACTION (2.692 Å)
Cite:Identifying ligand-binding hot spots in proteins using brominated fragments.
Acta Crystallogr.,Sect.F, 69, 2013
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