5ZLZ
| Structure of tPA and PAI-1 | Descriptor: | GLYCEROL, Plasminogen activator inhibitor 1, Tissue-type plasminogen activator | Authors: | Min, L, Huang, M. | Deposit date: | 2018-03-31 | Release date: | 2019-04-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.581 Å) | Cite: | Development of a PAI-1 trapping agent (PAItrap2) based on inactivated tPA-SPD and the crystal structure of PAItrap2 in complex with PAI-1 To Be Published
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3D2M
| Crystal structure of N-acetylglutamate synthase from Neisseria gonorrhoeae complexed with coenzyme A and L-glutamate | Descriptor: | COENZYME A, GLUTAMIC ACID, Putative acetylglutamate synthase | Authors: | Shi, D, Min, L, Jin, Z, Allewell, N.M, Tuchman, M. | Deposit date: | 2008-05-08 | Release date: | 2008-12-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Mechanism of Allosteric Inhibition of N-Acetyl-L-glutamate Synthase by L-Arginine. J.Biol.Chem., 284, 2009
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3D2P
| Crystal structure of N-acetylglutamate synthase from Neisseria gonorrhoeae complexed with coenzyme A and L-arginine | Descriptor: | ARGININE, COENZYME A, Putative acetylglutamate synthase | Authors: | Shi, D, Min, L, Jin, Z, Allewell, N.M, Tuchman, M. | Deposit date: | 2008-05-08 | Release date: | 2008-12-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Mechanism of Allosteric Inhibition of N-Acetyl-L-glutamate Synthase by L-Arginine. J.Biol.Chem., 284, 2009
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6AEX
| Crystal structure of unoccupied murine uPAR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor | Authors: | Min, L, Huang, M. | Deposit date: | 2018-08-06 | Release date: | 2019-07-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.393 Å) | Cite: | Crystal structure of the unoccupied murine urokinase-type plasminogen activator receptor (uPAR) reveals a tightly packed DII-DIII unit. Febs Lett., 593, 2019
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4H6Q
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4H6R
| Structure of reduced Deinococcus radiodurans proline dehydrogenase | Descriptor: | ACETATE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Proline dehydrogenase | Authors: | Min, L, Tanner, J.J. | Deposit date: | 2012-09-19 | Release date: | 2012-11-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structures and kinetics of monofunctional proline dehydrogenase provide insight into substrate recognition and conformational changes associated with flavin reduction and product release. Biochemistry, 51, 2012
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8XJ4
| Structure of prostatic acid phosphatase in human semen | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Prostatic acid phosphatase, alpha-D-mannopyranose, ... | Authors: | Liu, X.Z, Li, J.L, Deng, D, Wang, X. | Deposit date: | 2023-12-20 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Purification, identification and Cryo-EM structure of prostatic acid phosphatase in human semen Biochem.Biophys.Res.Commun., 702, 2024
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2N0W
| Mdmx-SJ212 | Descriptor: | 4-({(4S,5R)-4-(5-bromo-2-fluorophenyl)-5-(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, Protein Mdm4 | Authors: | Grace, C.R, Kriwacki, R.W. | Deposit date: | 2015-03-17 | Release date: | 2016-01-27 | Last modified: | 2016-05-04 | Method: | SOLUTION NMR | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery. J.Mol.Biol., 428, 2016
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2N06
| Mdmx-298 | Descriptor: | 4-[[(4S,5R)-5-(4-chlorophenyl)-4-(3-methoxyphenyl)-2-(4-methoxy-2-propan-2-yloxy-phenyl)-4,5-dihydroimidazol-1-yl]carbonyl]piperazin-2-one, Protein Mdm4 | Authors: | Grace, C.R, Kriwacki, R.W. | Deposit date: | 2015-03-04 | Release date: | 2016-01-27 | Last modified: | 2019-11-06 | Method: | SOLUTION NMR | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery. J.Mol.Biol., 428, 2016
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2N14
| Mdmx-295 | Descriptor: | 4-({(4S,5R)-4-(3-chlorophenyl)-5-(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, Protein Mdm4 | Authors: | Grace, C.R, Kriwacki, R.W. | Deposit date: | 2015-03-20 | Release date: | 2016-01-27 | Last modified: | 2016-05-04 | Method: | SOLUTION NMR | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery. J.Mol.Biol., 428, 2016
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2N0U
| Mdmx-057 | Descriptor: | 4-[(4S,5R)-4-(3-chlorophenyl)-5-(4-chlorophenyl)-1-(3-oxidanylidenepiperazin-1-yl)carbonyl-4,5-dihydroimidazol-2-yl]-3-propan-2-yloxy-benzenecarbonitrile, Protein Mdm4 | Authors: | Grace, C.R, Kriwacki, R.W. | Deposit date: | 2015-03-17 | Release date: | 2016-01-27 | Last modified: | 2016-05-04 | Method: | SOLUTION NMR | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery. J.Mol.Biol., 428, 2016
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2MWY
| Mdmx-p53 | Descriptor: | Cellular tumor antigen p53, Protein Mdm4 | Authors: | Grace, C.R. | Deposit date: | 2014-12-03 | Release date: | 2016-01-27 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery. J.Mol.Biol., 428, 2016
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2M03
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2M04
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8HF4
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8HF5
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8HF6
| Cryo-EM structure of nucleotide-bound ComA E647Q mutant | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Competence factor transporting ATP-binding protein/permease ComA | Authors: | Yu, L, Xin, X, Min, L. | Deposit date: | 2022-11-09 | Release date: | 2023-10-04 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of peptide secretion for Quorum sensing by ComA. Nat Commun, 14, 2023
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8HF7
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8K4B
| Cryo-EM structure of nucleotide-bound ComA with ZinC ion | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Competence factor transporting ATP-binding protein/permease ComA, ZINC ION | Authors: | Yu, L, Xin, X, Min, L, Feng, H. | Deposit date: | 2023-07-17 | Release date: | 2023-10-11 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of peptide secretion for Quorum sensing by ComA Nat Commun, 14, 2023
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8K7A
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4HNJ
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8I6Q
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