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7K3R
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BU of 7k3r by Molmil
Cryo-EM structure of AIM2-PYD filament
Descriptor: Interferon-inducible protein AIM2
Authors:Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H.
Deposit date:2020-09-12
Release date:2021-05-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome.
Nat Commun, 12, 2021
6MKS
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BU of 6mks by Molmil
Cryo-EM structure of NLRC4-CARD filament
Descriptor: Chimera protein of NLR family CARD domain-containing protein 4 and EGFP
Authors:Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H.
Deposit date:2018-09-26
Release date:2018-11-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of the NLRC4CARDfilament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly.
J. Biol. Chem., 293, 2018
7THZ
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BU of 7thz by Molmil
Structure of Leucine Rich Repeat Kinase 2's ROC domain interacting with the microtubule facing the plus end
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2
Authors:Matyszewski, M, Leschziner, A.E.
Deposit date:2022-01-12
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules.
Nat.Struct.Mol.Biol., 29, 2022
7THY
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BU of 7thy by Molmil
Structure of Leucine Rich Repeat Kinase 2's ROC domain interacting with the microtubule facing the minus end
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2
Authors:Matyszewski, M, Leschziner, A.E.
Deposit date:2022-01-12
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules.
Nat.Struct.Mol.Biol., 29, 2022
6VNO
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BU of 6vno by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
Authors:Leschziner, A, Deniston, C, Lahiri, I.
Deposit date:2020-01-29
Release date:2020-08-26
Last modified:2020-12-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP8
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BU of 6vp8 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor: Leucine-rich repeat serine/threonine-protein kinase 2
Authors:Leschziner, A, Deniston, C, Lahiri, I.
Deposit date:2020-02-01
Release date:2020-08-26
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP6
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BU of 6vp6 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
Authors:Leschziner, A, Deniston, C, Lahiri, I.
Deposit date:2020-02-01
Release date:2020-08-26
Last modified:2020-12-23
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP7
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BU of 6vp7 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor: Leucine-rich repeat serine/threonine-protein kinase 2
Authors:Leschziner, A, Deniston, C, Lahiri, I.
Deposit date:2020-02-01
Release date:2020-08-26
Last modified:2020-12-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020

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