Author results

1UFR
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CRYSTAL STRUCTURE OF TT1027 FROM THERMUS THERMOPHILUS HB8
Descriptor:pyr mRNA-binding attenuation protein, CHLORIDE ION
Authors:Matsuura, T., Sakai, H., Terada, T., Shirouzu, M., Kuramitsu, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-08
Release date:2003-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of TT1027 from Thermus thermophilus HB8
To be Published
1IQQ
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CRYSTAL STRUCTURE OF JAPANESE PEAR S3-RNASE
Descriptor:S3-RNase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Matsuura, T., Sakai, H., Norioka, S.
Deposit date:2001-07-25
Release date:2001-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure at 1.5-A resolution of Pyrus pyrifolia pistil ribonuclease responsible for gametophytic self-incompatibility.
J.Biol.Chem., 276, 2001
1VF7
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CRYSTAL STRUCTURE OF THE MEMBRANE FUSION PROTEIN, MEXA OF THE MULTIDRUG TRANSPORTER
Descriptor:Multidrug resistance protein mexA
Authors:Akama, H., Matsuura, T., Kashiwagi, S., Yoneyama, H., Tsukihara, T., Nakagawa, A., Nakae, T.
Deposit date:2004-04-09
Release date:2004-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the membrane fusion protein, MexA, of the multidrug transporter in Pseudomonas aeruginosa
J.Biol.Chem., 279, 2004
1UC8
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CRYSTAL STRUCTURE OF A LYSINE BIOSYNTHESIS ENZYME, LYSX, FROM THERMUS THERMOPHILUS HB8
Descriptor:lysine biosynthesis enzyme
Authors:Sakai, H., Vassylyeva, M.N., Matsuura, T., Sekine, S., Nishiyama, M., Terada, T., Shirouzu, M., Kuramitsu, S., Vassylyev, D.G., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-04-09
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a Lysine Biosynthesis Enzyme, LysX, from Thermus thermophilus HB8
J.Mol.Biol., 332, 2003
1UC9
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CRYSTAL STRUCTURE OF A LYSINE BIOSYNTHESIS ENZYME, LYSX, FROM THERMUS THERMOPHILUS HB8
Descriptor:lysine biosynthesis enzyme, ADENOSINE-5'-DIPHOSPHATE
Authors:Sakai, H., Vassylyeva, M.N., Matsuura, T., Sekine, S., Nishiyama, M., Terada, T., Shirouzu, M., Kuramitsu, S., Vassylyev, D.G., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-04-09
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal Structure of a Lysine Biosynthesis Enzyme, LysX, from Thermus thermophilus HB8
J.Mol.Biol., 332, 2003
1WCW
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CRYSTAL STRUCTURE OF UROPORPHYRINOGEN III SYNTHASE FROM AN EXTREMELY THERMOPHILIC BACTERIUM THERMUS THERMOPHILUS HB8 (WILD TYPE, NATIVE, FORM-1 CRYSTAL)
Descriptor:Uroporphyrinogen III synthase, GLYCEROL
Authors:Mizohata, E., Matsuura, T., Sakai, H., Murayama, K., Terada, T., Shirouzu, M., Kuramitsu, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-06
Release date:2005-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structure of Uroporphyrinogen III Synthase from Thermus thermophilus HB8
To be Published
1WCX
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CRYSTAL STRUCTURE OF MUTANT UROPORPHYRINOGEN III SYNTHASE FROM AN EXTREMELY THERMOPHILIC BACTERIUM THERMUS THERMOPHILUS HB8 (L75M/I193M/L248M, SEMET DERIVATIVE, FORM-1 CRYSTAL)
Descriptor:Uroporphyrinogen III Synthase, GLYCEROL
Authors:Mizohata, E., Matsuura, T., Murayama, K., Sakai, H., Terada, T., Shirouzu, M., Kuramitsu, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-06
Release date:2005-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Uroporphyrinogen III Synthase from Thermus thermophilus HB8
To be Published
1WD7
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CRYSTAL STRUCTURE OF UROPORPHYRINOGEN III SYNTHASE FROM AN EXTREMELY THERMOPHILIC BACTERIUM THERMUS THERMOPHILUS HB8 (WILD TYPE, NATIVE, FORM-2 CRYSTAL)
Descriptor:Uroporphyrinogen III Synthase
Authors:Mizohata, E., Matsuura, T., Sakai, H., Murayama, K., Terada, T., Shirouzu, M., Kuramitsu, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-12
Release date:2004-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (Wild type, Native, Form-2 crystal)
to be published
1X1N
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STRUCTURE DETERMINATION AND REFINEMENT AT 1.8 A RESOLUTION OF DISPROPORTIONATING ENZYME FROM POTATO
Descriptor:4-alpha-glucanotransferase, CALCIUM ION, GLYCEROL
Authors:Imamura, K., Matsuura, T., Takaha, T., Fujii, K., Nakagawa, A., Kusunoki, M., Nitta, Y.
Deposit date:2005-04-08
Release date:2006-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure determination and refinement at 1.8 A resolution of Disproportionating Enzyme from Potato
to be published
2DFV
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HYPERTHERMOPHILIC THREONINE DEHYDROGENASE FROM PYROCOCCUS HORIKOSHII
Descriptor:Probable L-threonine 3-dehydrogenase, ZINC ION, SULFATE ION, ...
Authors:Ishikawa, K., Higashi, N., Nakamura, T., Matsuura, T., Nakagawa, A.
Deposit date:2006-03-03
Release date:2007-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The first crystal structure of L-threonine dehydrogenase.
J.Mol.Biol., 366, 2007
2D4D
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THE CRYSTAL STRUCTURE OF HUMAN BETA2-MICROGLOBULIN, L39W W60F W95F MUTANT
Descriptor:Beta-2-microglobulin, SODIUM ION
Authors:Iwata, K., Matsuura, T., Nakagawa, A., Goto, Y.
Deposit date:2005-10-17
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformation of Amyloid Fibrils of beta2-Microglobulin Probed by Tryptophan Mutagenesis
J.Biol.Chem., 281, 2006
2D4F
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THE CRYSTAL STRUCTURE OF HUMAN BETA2-MICROGLOBULIN
Descriptor:Beta-2-microglobulin, SODIUM ION
Authors:Iwata, K., Matsuura, T., Nakagawa, A., Goto, Y.
Deposit date:2005-10-18
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conformation of Amyloid Fibrils of beta2-Microglobulin Probed by Tryptophan Mutagenesis
J.Biol.Chem., 281, 2006
2YXF
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THE HIGH RESOLUTION CRYSTAL STRUCTURE OF BETA2-MICROGLOBULIN UNDER PHYSIOLOGICAL CONDITIONS
Descriptor:Beta-2-microglobulin
Authors:Iwata, K., Matsuura, T., Nakagawa, A., Goto, Y.
Deposit date:2007-04-26
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:High-resolution Crystal Structure of {beta}2-Microglobulin Formed at pH 7.0
J.Biochem.(Tokyo), 142, 2007
3A34
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EFFECT OF ARIGININE ON LYSOZYME
Descriptor:Lysozyme C, ARGININE, CHLORIDE ION, ...
Authors:Ito, L., Shiraki, K., Matsuura, T., Yamaguchi, H.
Deposit date:2009-06-09
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Implication of Arg bindings on aromatic surfaces of lysozyme for additives that prevent protein aggregation
TO BE PUBLISHED
3EMS
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EFFECT OF ARIGININE ON LYSOZYME
Descriptor:Lysozyme C, ARGININE, CHLORIDE ION, ...
Authors:Ito, L., Shiraki, K., Matsuura, T., Yamaguhi, H.
Deposit date:2008-09-25
Release date:2008-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:Effect of Ariginine on lysozyme
to be published
3VW9
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HUMAN GLYOXALASE I WITH AN N-HYDROXYPYRIDONE INHIBITOR
Descriptor:Lactoylglutathione lyase, ZINC ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Fukami, T.A., Irie, M., Matsuura, T.
Deposit date:2012-08-10
Release date:2012-12-12
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Design and evaluation of azaindole-substituted N-hydroxypyridones as glyoxalase I inhibitors
Bioorg.Med.Chem.Lett., 22, 2012
3W0T
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HUMAN GLYOXALASE I WITH AN N-HYDROXYPYRIDONE DERIVATIVE INHIBITOR
Descriptor:Lactoylglutathione lyase, ZINC ION, N-[3-(1-hydroxy-6-oxo-4-phenyl-1,6-dihydropyridin-2-yl)phenyl]methanesulfonamide, ...
Authors:Fukami, T.A., Irie, M., Matsuura, T.
Deposit date:2012-11-02
Release date:2013-11-06
Method:X-RAY DIFFRACTION (1.351 Å)
Cite:N-Hydroxypyridone-based glyoxalase I inhibitors mimicking binding interactions of the substrate
To be Published
3W0U
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HUMAN GLYOXALASE I WITH AN N-HYDROXYPYRIDONE INHIBITOR
Descriptor:Lactoylglutathione lyase, ZINC ION, N-[3-(1-Hydroxy-6-oxo-4-phenyl-1,6-dihydro-pyridin-2-yl)-5-methanesulfonylamino-phenyl]-methanesulfonamide
Authors:Fukami, T.A., Irie, M., Matsuura, T.
Deposit date:2012-11-02
Release date:2013-11-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:N-Hydroxypyridone-based glyoxalase I inhibitors mimicking binding interactions of the substrate
to be published
5JGA
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CRYSTAL STRUCTURE OF HUMAN TAK1/TAB1 FUSION PROTEIN IN COMPLEX WITH LIGAND 11C
Descriptor:TAK1 kinase - TAB1 chimera fusion protein, N-[5-(4-methylpiperazine-1-carbonyl)[1,1'-biphenyl]-2-yl]-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide
Authors:Irie, M., Nakamura, M., Fukami, T.A., Matsuura, T., Morishima, K.
Deposit date:2016-04-19
Release date:2016-07-27
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of a potent and highly selective transforming growth factor beta receptor-associated kinase 1 (TAK1) inhibitor by structure based drug design (SBDD)
Bioorg.Med.Chem., 24, 2016
5JGB
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CRYSTAL STRUCTURE OF HUMAN TAK1/TAB1 FUSION PROTEIN IN COMPLEX WITH LIGAND 10
Descriptor:TAK1 kinase - TAB1 chimera fusion protein, N-(2-methoxy-4-{[3-(4-methylpiperazin-1-yl)propyl]carbamoyl}phenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide
Authors:Irie, M., Nakamura, M., Fukami, T.A., Matsuura, T., Morishima, K.
Deposit date:2016-04-20
Release date:2016-07-27
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery of a potent and highly selective transforming growth factor beta receptor-associated kinase 1 (TAK1) inhibitor by structure based drug design (SBDD)
Bioorg.Med.Chem., 24, 2016
5JGD
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CRYSTAL STRUCTURE OF HUMAN TAK1/TAB1 FUSION PROTEIN IN COMPLEX WITH LIGAND 12
Descriptor:TAK1 kinase - TAB1 chimera fusion protein, N-(2-isopropoxy-3-(4-methylpiperazine-1-carbonyl)phenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide
Authors:Irie, M., Nakamura, M., Fukami, T.A., Matsuura, T., Morishima, K.
Deposit date:2016-04-20
Release date:2016-07-27
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Discovery of a potent and highly selective transforming growth factor beta receptor-associated kinase 1 (TAK1) inhibitor by structure based drug design (SBDD)
Bioorg.Med.Chem., 24, 2016
3AGG
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X-RAY ANALYSIS OF LYSOZYME IN THE ABSENCE OF ARG
Descriptor:Lysozyme C, CHLORIDE ION, SODIUM ION, ...
Authors:Ito, L., Shiraki, K., Hasegawa, K., Baba, S., Kumasaka, T.
Deposit date:2010-03-31
Release date:2011-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High-resolution X-ray analysis reveals binding of arginine to aromatic residues of lysozyme surface: implication of suppression of protein aggregation by arginine
Protein Eng.Des.Sel., 24, 2011
3AGH
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X-RAY ANALYSIS OF LYSOZYME IN THE PRESENCE OF 200 MM ARG
Descriptor:Lysozyme C, ACETATE ION, SODIUM ION, ...
Authors:Ito, L., Shiraki, K., Hasegawa, K., Baba, S., Kumasaka, T.
Deposit date:2010-03-31
Release date:2011-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:High-resolution X-ray analysis reveals binding of arginine to aromatic residues of lysozyme surface: implication of suppression of protein aggregation by arginine
Protein Eng.Des.Sel., 24, 2011
3AGI
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HIGH RESOLUTION X-RAY ANALYSIS OF ARG-LYSOZYME COMPLEX IN THE PRESENCE OF 500 MM ARG
Descriptor:Lysozyme C, ACETATE ION, ARGININE, ...
Authors:Ito, L., Shiraki, K., Hasegawa, K., Baba, S., Kumasaka, T.
Deposit date:2010-03-31
Release date:2011-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:High-resolution X-ray analysis reveals binding of arginine to aromatic residues of lysozyme surface: implication of suppression of protein aggregation by arginine
Protein Eng.Des.Sel., 24, 2011
5GJD
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CRYSTAL STRUCTURE OF HUMAN TAK1/TAB1 FUSION PROTEIN IN COMPLEX WITH LIGAND 2
Descriptor:TAK1 kinase - TAB1 chimera fusion protein, 1-(4-((1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)-3-(5-(4-methylpiperazin-1-yl)naphthalen-2-yl)urea
Authors:Irie, M., Nakamura, M., Fukami, T.A., Matsuura, T., Morishima, K.
Deposit date:2016-06-29
Release date:2016-11-16
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Development of a Method for Converting a TAK1 Type I Inhibitor into a Type II or c-Helix-Out Inhibitor by Structure-Based Drug Design (SBDD)
Chem.Pharm.Bull., 64, 2016
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