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1YGS
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BU of 1ygs by Molmil
CRYSTAL STRUCTURE OF THE SMAD4 TUMOR SUPPRESSOR C-TERMINAL DOMAIN
Descriptor: SMAD4
Authors:Shi, Y, Hata, A, Lo, R.S, Massague, J, Pavletich, N.P.
Deposit date:1997-10-03
Release date:1998-07-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A structural basis for mutational inactivation of the tumour suppressor Smad4.
Nature, 388, 1997
1B6C
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BU of 1b6c by Molmil
CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF THE TYPE I TGF-BETA RECEPTOR IN COMPLEX WITH FKBP12
Descriptor: FK506-BINDING PROTEIN, SULFATE ION, TGF-B SUPERFAMILY RECEPTOR TYPE I
Authors:Huse, M, Chen, Y.-G, Massague, J, Kuriyan, J.
Deposit date:1999-01-13
Release date:1999-06-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12.
Cell(Cambridge,Mass.), 96, 1999
1IAS
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BU of 1ias by Molmil
CYTOPLASMIC DOMAIN OF UNPHOSPHORYLATED TYPE I TGF-BETA RECEPTOR CRYSTALLIZED WITHOUT FKBP12
Descriptor: SULFATE ION, TGF-BETA RECEPTOR TYPE I
Authors:Huse, M, Muir, T.W, Chen, Y.-G, Kuriyan, J, Massague, J.
Deposit date:2001-03-23
Release date:2001-10-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The TGF beta receptor activation process: an inhibitor- to substrate-binding switch.
Mol.Cell, 8, 2001
1KHX
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BU of 1khx by Molmil
Crystal structure of a phosphorylated Smad2
Descriptor: Smad2
Authors:Wu, J.-W, Hu, M, Chai, J, Seoane, J, Huse, M, Kyin, S, Muir, T.W, Fairman, R, Massague, J, Shi, Y.
Deposit date:2001-12-01
Release date:2002-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling.
Mol.Cell, 8, 2001
1OZJ
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BU of 1ozj by Molmil
Crystal structure of Smad3-MH1 bound to DNA at 2.4 A resolution
Descriptor: SMAD 3, Smad binding element, ZINC ION
Authors:Chai, J, Wu, J.-W, Yan, N, Massague, J, Pavletich, N.P, Shi, Y.
Deposit date:2003-04-09
Release date:2004-03-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Features of a Smad3 MH1-DNA complex. Roles of water and zinc in DNA binding.
J.Biol.Chem., 278, 2003
2LAZ
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BU of 2laz by Molmil
Structure of the first WW domain of human Smurf1 in complex with a mono-phosphorylated human Smad1 derived peptide
Descriptor: E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1
Authors:Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
Deposit date:2011-03-22
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LAW
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BU of 2law by Molmil
Structure of the second WW domain from human YAP in complex with a human Smad1 derived peptide
Descriptor: Mothers against decapentaplegic homolog 1, Yorkie homolog
Authors:Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
Deposit date:2011-03-22
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LAX
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BU of 2lax by Molmil
Structure of first WW domain of human YAP in complex with a human Smad1 doubly-phosphorilated derived peptide.
Descriptor: Mothers against decapentaplegic homolog 1, Yorkie homolog
Authors:Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
Deposit date:2011-03-22
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LB0
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BU of 2lb0 by Molmil
Structure of the first WW domain of human Smurf1 in complex with a di-phosphorylated human Smad1 derived peptide
Descriptor: E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1
Authors:Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
Deposit date:2011-03-22
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LTV
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BU of 2ltv by Molmil
YAP WW2 in complex with a Smad7 derived peptide
Descriptor: Smad7 derived peptide, Yorkie homolog
Authors:Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
Deposit date:2012-06-04
Release date:2012-11-21
Method:SOLUTION NMR
Cite:Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
2LB3
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BU of 2lb3 by Molmil
Structure of the WW domain of PIN1 in complex with a human phosphorylated Smad3 derived peptide
Descriptor: Mothers against decapentaplegic homolog 2, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
Deposit date:2011-03-22
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LB2
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BU of 2lb2 by Molmil
Structure of the second domain of human Nedd4L in complex with a phosphorylated pTPY motif derived from human Smad3
Descriptor: E3 ubiquitin-protein ligase NEDD4-like, Mothers against decapentaplegic homolog 3
Authors:Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
Deposit date:2011-03-22
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LB1
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BU of 2lb1 by Molmil
Structure of the second domain of human Smurf1 in complex with a human Smad1 derived peptide
Descriptor: E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1
Authors:Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
Deposit date:2011-03-22
Release date:2011-07-06
Last modified:2016-04-27
Method:SOLUTION NMR
Cite:A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LAY
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BU of 2lay by Molmil
Structure of the first WW domain of human YAP in complex with a phosphorylated human Smad1 derived peptide
Descriptor: Mothers against decapentaplegic homolog 1, Yorkie homolog
Authors:Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
Deposit date:2011-03-22
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LAJ
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BU of 2laj by Molmil
Third WW domain of human Nedd4L in complex with doubly phosphorylated human smad3 derived peptide
Descriptor: E3 ubiquitin-protein ligase NEDD4-like, Mothers against decapentaplegic homolog 3
Authors:Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
Deposit date:2011-03-16
Release date:2011-07-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LTW
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BU of 2ltw by Molmil
YAP WW1 in complex with a Smad7 derived peptide
Descriptor: Smad7 derived peptide, Yorkie homolog
Authors:Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
Deposit date:2012-06-04
Release date:2012-11-21
Method:SOLUTION NMR
Cite:Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
2LTX
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BU of 2ltx by Molmil
Smurf1 WW2 domain in complex with a Smad7 derived peptide
Descriptor: E3 ubiquitin-protein ligase SMURF1, Smad7 derived peptide
Authors:Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
Deposit date:2012-06-04
Release date:2012-11-21
Method:SOLUTION NMR
Cite:Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
2LTY
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BU of 2lty by Molmil
NEDD4L WW2 domain in complex with a Smad7 derived peptide
Descriptor: E3 ubiquitin-protein ligase NEDD4-like, Smad7 derived peptide
Authors:Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
Deposit date:2012-06-04
Release date:2012-11-21
Method:SOLUTION NMR
Cite:Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
2LTZ
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BU of 2ltz by Molmil
Smurf2 WW3 domain in complex with a Smad7 derived peptide
Descriptor: E3 ubiquitin-protein ligase SMURF2, Smad7 derived peptide
Authors:Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
Deposit date:2012-06-04
Release date:2012-11-21
Method:SOLUTION NMR
Cite:Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
6H3R
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BU of 6h3r by Molmil
Crystal structure of Smad2 without exon -MH1 bound to the CAGAC site.
Descriptor: DNA (5'-D(P*GP*AP*GP*TP*GP*TP*CP*TP*GP*CP*AP*GP*AP*CP*AP*CP*TP*C)-3'), Mothers against decapentaplegic homolog, ZINC ION
Authors:Kaczmarska, Z, Marquez, J.A, Macias, M.J.
Deposit date:2018-07-19
Release date:2019-09-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-beta signaling
Genes Dev., 2020
3U5O
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BU of 3u5o by Molmil
Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-22)K9me3K14acK18ac histone peptide
Descriptor: E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION
Authors:Wang, Z, Patel, D.J.
Deposit date:2011-10-11
Release date:2012-01-18
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A poised chromatin platform for TGF-beta access to master regulators
Cell(Cambridge,Mass.), 147, 2011
1FIN
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BU of 1fin by Molmil
CYCLIN A-CYCLIN-DEPENDENT KINASE 2 COMPLEX
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN A, CYCLIN-DEPENDENT KINASE 2
Authors:Jeffrey, P.D, Russo, A.A, Pavletich, N.P.
Deposit date:1996-07-14
Release date:1997-01-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex.
Nature, 376, 1995
1DEV
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BU of 1dev by Molmil
CRYSTAL STRUCTURE OF SMAD2 MH2 DOMAIN BOUND TO THE SMAD-BINDING DOMAIN OF SARA
Descriptor: MAD (mothers against decapentaplegic, Drosophila) homolog 2, Smad anchor for receptor activation
Authors:Shi, Y, Wu, G.
Deposit date:1999-11-15
Release date:2000-01-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of Smad2 recognition by the Smad anchor for receptor activation.
Science, 287, 2000
3U5M
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BU of 3u5m by Molmil
Crystal structure of TRIM33 PHD-Bromo in the free state
Descriptor: CALCIUM ION, E3 ubiquitin-protein ligase TRIM33, ZINC ION
Authors:Wang, Z, Patel, D.J.
Deposit date:2011-10-11
Release date:2012-01-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:A poised chromatin platform for TGF-beta access to master regulators
Cell(Cambridge,Mass.), 147, 2011
3U5P
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BU of 3u5p by Molmil
Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-28)K9me3K14acK18acK23ac histone peptide
Descriptor: E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION
Authors:Wang, Z, Patel, D.J.
Deposit date:2011-10-11
Release date:2012-01-18
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A poised chromatin platform for TGF-beta access to master regulators
Cell(Cambridge,Mass.), 147, 2011

 

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