Author results

1FYV
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CRYSTAL STRUCTURE OF THE TIR DOMAIN OF HUMAN TLR1
Descriptor:TOLL-LIKE RECEPTOR 1
Authors:Xu, Y., Tao, X., Shen, B., Horng, T., Medzhitov, R., Manley, J.L., Tong, L.
Deposit date:2000-10-03
Release date:2000-11-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Nature, 408, 2000
1FYW
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CRYSTAL STRUCTURE OF THE TIR DOMAIN OF HUMAN TLR2
Descriptor:TOLL-LIKE RECEPTOR 2
Authors:Xu, Y., Tao, X., Shen, B., Horng, T., Medzhitov, R., Manley, J.L., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2000-10-03
Release date:2000-11-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Nature, 408, 2000
1FYX
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CRYSTAL STRUCTURE OF P681H MUTANT OF TIR DOMAIN OF HUMAN TLR2
Descriptor:TOLL-LIKE RECEPTOR 2
Authors:Xu, Y., Tao, X., Shen, B., Horng, T., Medzhitov, R., Manley, J.L., Tong, L.
Deposit date:2000-10-03
Release date:2000-11-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Nature, 408, 2000
2OND
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CRYSTAL STRUCTURE OF THE HAT-C DOMAIN OF MURINE CSTF-77
Descriptor:Cleavage stimulation factor 77 kDa subunit
Authors:Bai, Y., Auperin, T.C., Chou, C.-Y., Chang, G.-G., Manley, J.L., Tong, L.
Deposit date:2007-01-23
Release date:2007-04-10
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Murine CstF-77: Dimeric Association and Implications for Polyadenylation of mRNA Precursors.
Mol.Cell, 25, 2007
2OOE
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CRYSTAL STRUCTURE OF HAT DOMAIN OF MURINE CSTF-77
Descriptor:Cleavage stimulation factor 77 kDa subunit
Authors:Bai, Y., Auperin, T.C., Chou, C.-Y., Chang, G.-G., Manley, J.L., Tong, L.
Deposit date:2007-01-25
Release date:2007-04-10
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of Murine CstF-77: Dimeric Association and Implications for Polyadenylation of mRNA Precursors.
Mol.Cell, 25, 2007
2I7T
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STRUCTURE OF HUMAN CPSF-73
Descriptor:Cleavage and polyadenylation specificity factor 73 kDa subunit, ZINC ION, SULFATE ION
Authors:Mandel, C.R., Zhang, H., Tong, L.
Deposit date:2006-08-31
Release date:2007-01-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.
Nature, 444, 2006
2I7V
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STRUCTURE OF HUMAN CPSF-73
Descriptor:Cleavage and polyadenylation specificity factor 73 kDa subunit, ZINC ION, SULFATE ION
Authors:Mandel, C.R., Zhang, H., Tong, L.
Deposit date:2006-08-31
Release date:2007-01-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.
Nature, 444, 2006
2I7X
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STRUCTURE OF YEAST CPSF-100 (YDH1P)
Descriptor:Protein CFT2
Authors:Mandel, C.R., Zhang, H., Gebauer, D., Tong, L.
Deposit date:2006-08-31
Release date:2007-01-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.
Nature, 444, 2006
3FQD
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CRYSTAL STRUCTURE OF THE S. POMBE RAT1-RAI1 COMPLEX
Descriptor:5'-3' exoribonuclease 2, Protein din1, MAGNESIUM ION, ...
Authors:Xiang, S., Tong, L.
Deposit date:2009-01-07
Release date:2009-02-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.
Nature, 458, 2009
3FQG
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CRYSTAL STRUCTURE OF THE S. POMBE RAI1
Descriptor:Protein din1, MAGNESIUM ION
Authors:Xiang, S., Tong, L.
Deposit date:2009-01-07
Release date:2009-02-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.
Nature, 458, 2009
3FQI
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CRYSTAL STRUCTURE OF THE MOUSE DOM3Z
Descriptor:Protein Dom3Z, MAGNESIUM ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Xiang, S., Tong, L.
Deposit date:2009-01-07
Release date:2009-02-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.013 Å)
Cite:Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.
Nature, 458, 2009
3FQJ
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CRYSTAL STRUCTURE OF THE MOUSE DOM3Z IN COMPLEX WITH GDP
Descriptor:Protein Dom3Z, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Xiang, S., Tong, L.
Deposit date:2009-01-07
Release date:2009-02-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.623 Å)
Cite:Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.
Nature, 458, 2009
3O2Q
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CRYSTAL STRUCTURE OF THE HUMAN SYMPLEKIN-SSU72-CTD PHOSPHOPEPTIDE COMPLEX
Descriptor:Symplekin, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, RNA polymerase II CTD Serine-5 phosphopeptide, ...
Authors:Tong, L., Xiang, K.
Deposit date:2010-07-22
Release date:2010-10-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.
Nature, 467, 2010
3O2S
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CRYSTAL STRUCTURE OF THE HUMAN SYMPLEKIN-SSU72 COMPLEX
Descriptor:Symplekin, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, PHOSPHATE ION
Authors:Tong, L., Xiang, K.
Deposit date:2010-07-22
Release date:2010-10-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.
Nature, 467, 2010
3O2T
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN SYMPLEKIN
Descriptor:Symplekin, 1,2-ETHANEDIOL
Authors:Tong, L., Xiang, K., Xiang, S.
Deposit date:2010-07-22
Release date:2010-10-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.
Nature, 467, 2010
3ODR
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN SYMPLEKIN
Descriptor:Symplekin, 1,2-ETHANEDIOL
Authors:Tong, L., Xiang, K.
Deposit date:2010-08-11
Release date:2010-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.
Nature, 467, 2010
3ODS
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CRYSTAL STRUCTURE OF THE K185A MUTANT OF THE N-TERMINAL DOMAIN OF HUMAN SYMPLEKIN
Descriptor:Symplekin, 1,2-ETHANEDIOL
Authors:Tong, L., Xiang, K.
Deposit date:2010-08-11
Release date:2010-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.
Nature, 467, 2010
3PIE
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CRYSTAL STRUCTURE OF THE 5'->3' EXORIBONUCLEASE XRN1, E178Q MUTANT
Descriptor:5'->3' EXORIBONUCLEASE (Xrn1)
Authors:Chang, J.H., Xiang, S., Tong, L.
Deposit date:2010-11-06
Release date:2011-02-09
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and biochemical studies of the 5' -> 3' exoribonuclease Xrn1.
Nat.Struct.Mol.Biol., 18, 2011
3PIF
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CRYSTAL STRUCTURE OF THE 5'->3' EXORIBONUCLEASE XRN1, E178Q MUTANT IN COMPLEX WITH MANGANESE
Descriptor:5'->3' EXORIBONUCLEASE (xrn1), MANGANESE (II) ION
Authors:Chang, J.H., Xiang, S., Tong, L.
Deposit date:2010-11-06
Release date:2011-02-09
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structural and biochemical studies of the 5' -> 3' exoribonuclease Xrn1.
Nat.Struct.Mol.Biol., 18, 2011
3PQ1
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL POLY(A) POLYMERASE (PAPD1)
Descriptor:Poly(A) RNA polymerase
Authors:Bai, Y., Srivastava, S.K., Chang, J.H., Tong, L.
Deposit date:2010-11-25
Release date:2011-03-30
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for dimerization and activity of human PAPD1, a noncanonical poly(A) polymerase.
Mol.Cell, 41, 2011
4FC8
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CRYSTAL STRUCTURE OF TRANSCRIPTION REGULATOR PROTEIN RTR1 FROM KLUYVEROMYCES LACTIS
Descriptor:transcription protein Rtr1, ZINC ION
Authors:Xiang, K., Tong, L.
Deposit date:2012-05-24
Release date:2012-07-25
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity.
Nat Commun, 3, 2012
4H3H
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF HUMAN SYMPLEKIN NTD, HUMAN SSU72 AND A RNA POYMERASE II CTD PEPTIDE PHOSPHORYLATED AT SER-7
Descriptor:Symplekin, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, Pol II CTD peptide, ...
Authors:Xiang, K., Tong, L.
Deposit date:2012-09-13
Release date:2012-10-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72.
Genes Dev., 26, 2012
4H3K
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF HUMAN SYMPLEKIN NTD, HUMAN SSU72 AND A RNA POLYMERASE II CTD PEPTIDE PHOSPHORYLATED AT SER-2, SER-5 AND SER-7
Descriptor:Symplekin, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, Hexapeptide, ...
Authors:Xiang, K., Tong, L.
Deposit date:2012-09-13
Release date:2012-10-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72.
Genes Dev., 26, 2012
6BLY
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CRYO-EM STRUCTURE OF HUMAN CPSF-160-WDR33 COMPLEX AT 3.36A RESOLUTION
Descriptor:Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33
Authors:Sun, Y., Zhang, Y., Hamilton, K., Walz, T., Tong, L.
Deposit date:2017-11-12
Release date:2017-11-22
Last modified:2018-02-28
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BM0
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CRYO-EM STRUCTURE OF HUMAN CPSF-160-WDR33 COMPLEX AT 3.8 A RESOLUTION
Descriptor:Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33
Authors:Sun, Y., Zhang, Y., Hamilton, K., Walz, T., Tong, L.
Deposit date:2017-11-12
Release date:2017-11-22
Last modified:2018-02-28
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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