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2YEV
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STRUCTURE OF CAA3-TYPE CYTOCHROME OXIDASE
Descriptor:CYTOCHROME C OXIDASE POLYPEPTIDE I+III, CYTOCHROME C OXIDASE SUBUNIT 2, CAA3-TYPE CYTOCHROME OXIDASE SUBUNIT IV, ...
Authors:Lyons, J.A., Aragao, D., Soulimane, T., Caffrey, M.
Deposit date:2011-03-31
Release date:2012-05-23
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural Insights Into Electron Transfer in Caa3-Type Cytochrome Oxidases.
Nature, 487, 2012
4D2B
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STRUCTURE OF A LIGAND FREE POT FAMILY PEPTIDE TRANSPORTER
Descriptor:DI-OR TRIPEPTIDE\:H+ SYMPORTER, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Lyons, J.A., Parker, J.L., Solcan, N., Brinth, A., Li, D., Shah, S.T.A., Caffrey, M., Newstead, S.
Deposit date:2014-05-09
Release date:2014-06-25
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
4D2C
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STRUCTURE OF A DI PEPTIDE BOUND POT FAMILY PEPTIDE TRANSPORTER
Descriptor:Di-or tripeptide:H+ symporter, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Lyons, J.A., Parker, J.L., Solcan, N., Brinth, A., Li, D., Shah, S.T.A., Caffrey, M., Newstead, S.
Deposit date:2014-05-09
Release date:2014-06-25
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
4D2D
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STRUCTURE OF A TRI PEPTIDE BOUND POT FAMILY PEPTIDE TRANSPORTER
Descriptor:DI-OR TRIPEPTIDE\:H+ SYMPORTER, ALANINE-TRIPEPTIDE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Lyons, J.A., Parker, J.L., Solcan, N., Brinth, A., Li, D., Shah, S.T.A., Caffrey, M., Newstead, S.
Deposit date:2014-05-09
Release date:2014-06-25
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (2.522 Å)
Cite:Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
4UVM
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IN MESO CRYSTAL STRUCTURE OF THE POT FAMILY TRANSPORTER PEPTSO
Descriptor:GLUTATHIONE UPTAKE TRANSPORTER, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE
Authors:Lyons, J.A., Solcan, N., Caffrey, M., Newstead, S.
Deposit date:2014-08-07
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Gating Topology of the Proton-Coupled Oligopeptide Symporters.
Structure, 23, 2015
4US3
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CRYSTAL STRUCTURE OF THE BACTERIAL NSS MEMBER MHST IN AN OCCLUDED INWARD-FACING STATE
Descriptor:TRANSPORTER, TRYPTOPHAN, SODIUM ION, ...
Authors:Malinauskaite, L., Quick, M., Reinhard, L., Lyons, J.A., Yano, H., Javitch, J.A., Nissen, P.
Deposit date:2014-07-02
Release date:2014-09-24
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.098 Å)
Cite:A Mechanism for Intracellular Release of Na+ by Neurotransmitter/Sodium Symporters
Nat.Struct.Mol.Biol., 21, 2014
4US4
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CRYSTAL STRUCTURE OF THE BACTERIAL NSS MEMBER MHST IN AN OCCLUDED INWARD-FACING STATE (LIPIDIC CUBIC PHASE FORM)
Descriptor:TRANSPORTER, TRYPTOPHAN, SODIUM ION, ...
Authors:Malinauskaite, L., Quick, M., Reinhard, L., Lyons, J.A., Yano, H., Javitch, J.A., Nissen, P.
Deposit date:2014-07-02
Release date:2014-09-24
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Mechanism for Intracellular Release of Na+ by Neurotransmitter/Sodium Symporters
Nat.Struct.Mol.Biol., 21, 2014
3PDS
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IRREVERSIBLE AGONIST-BETA2 ADRENOCEPTOR COMPLEX
Descriptor:Fusion protein Beta-2 adrenergic receptor/Lysozyme, 8-hydroxy-5-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(3-sulfanylpropoxy)phenyl]ethyl}amino)ethyl]quinolin-2(1H)-one, CHOLESTEROL, ...
Authors:Rosenbaum, D.M., Zhang, C., Lyons, J.A., Holl, R., Aragao, D., Arlow, D.H., Rasmussen, S.G.F., Choi, H.-J., DeVree, B.T., Sunahara, R.K., Chae, P.S., Gellman, S.H., Dror, R.O., Shaw, D.E., Weis, W.I., Caffrey, M., Gmeiner, P., Kobilka, B.K.
Deposit date:2010-10-24
Release date:2011-01-12
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure and function of an irreversible agonist-beta(2) adrenoceptor complex
Nature, 469, 2011
3SN6
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CRYSTAL STRUCTURE OF THE BETA2 ADRENERGIC RECEPTOR-GS PROTEIN COMPLEX
Descriptor:Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Rasmussen, S.G.F., DeVree, B.T., Zou, Y., Kruse, A.C., Chung, K.Y., Kobilka, T.S., Thian, F.S., Chae, P.S., Pardon, E., Calinski, D., Mathiesen, J.M., Shah, S.T.A., Lyons, J.A., Caffrey, M., Gellman, S.H., Steyaert, J., Skiniotis, G., Weis, W.I., Sunahara, R.K., Kobilka, B.K.
Deposit date:2011-06-28
Release date:2011-07-20
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the beta2 adrenergic receptor-Gs protein complex
Nature, 477, 2011
3ZE3
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - DELTA7
Descriptor:DIACYLGLYCEROL KINASE, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Li, D., Pye, V.E., Lyons, J.A., Vogeley, L., Aragao, D., Caffrey, M.
Deposit date:2012-12-03
Release date:2013-05-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
3ZE4
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - WILD-TYPE
Descriptor:DIACYLGLYCEROL KINASE
Authors:Li, D., Lyons, J.A., Pye, V.E., Vogeley, L., Aragao, D., Caffrey, M.
Deposit date:2012-12-03
Release date:2013-05-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.702 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
3ZE5
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - DELTA4
Descriptor:DIACYLGLYCEROL KINASE
Authors:Li, D., Vogeley, L., Pye, V.E., Lyons, J.A., Aragao, D., Caffrey, M.
Deposit date:2012-12-03
Release date:2013-05-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
4PRU
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CRYSTAL STRUCTURE OF DIMETHYLLYSINE HEN EGG-WHITE LYSOZYME IN COMPLEX WITH SCLX4 AT 2.2 A RESOLUTION
Descriptor:Lysozyme C, 25,26,27,28-tetrahydroxypentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-5,11,17,23-tetrasulfonic acid, GLYCEROL
Authors:McGovern, R.E., Lyons, J.A., Crowley, P.B.
Deposit date:2014-03-06
Release date:2014-11-12
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural study of a small molecule receptor bound to dimethyllysine in lysozyme.
Chem Sci, 6, 2015
6ROH
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CRYO-EM STRUCTURE OF THE AUTOINHIBITED DRS2P-CDC50P
Descriptor:Probable phospholipid-transporting ATPase DRS2, Cell division control protein 50, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ...
Authors:Timcenko, M., Lyons, J.A., Januliene, D., Ulstrup, J.J., Dieudonne, T., Montigny, C., Ash, M.R., Karlsen, J.L., Boesen, T., Kuhlbrandt, W., Lenoir, G., Moeller, A., Nissen, P.
Deposit date:2019-05-13
Release date:2019-07-03
Last modified:2019-07-31
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure and autoregulation of a P4-ATPase lipid flippase.
Nature, 571, 2019
6ROI
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CRYO-EM STRUCTURE OF THE PARTIALLY ACTIVATED DRS2P-CDC50P
Descriptor:Probable phospholipid-transporting ATPase DRS2, Cell division control protein 50, MAGNESIUM ION, ...
Authors:Timcenko, M., Lyons, J.A., Januliene, D., Ulstrup, J.J., Dieudonne, T., Montigny, C., Ash, M.R., Karlsen, J.L., Boesen, T., Kuhlbrandt, W., Lenoir, G., Moeller, A., Nissen, P.
Deposit date:2019-05-13
Release date:2019-07-03
Last modified:2019-07-31
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure and autoregulation of a P4-ATPase lipid flippase.
Nature, 571, 2019
6ROJ
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CRYO-EM STRUCTURE OF THE ACTIVATED DRS2P-CDC50P
Descriptor:Probable phospholipid-transporting ATPase DRS2,Oxaloacetate decarboxylase alpha chain, Cell division control protein 50, MAGNESIUM ION, ...
Authors:Timcenko, M., Lyons, J.A., Januliene, D., Ulstrup, J.J., Dieudonne, T., Montigny, C., Ash, M.R., Karlsen, J.L., Boesen, T., Kuhlbrandt, W., Lenoir, G., Moeller, A., Nissen, P.
Deposit date:2019-05-13
Release date:2019-07-03
Last modified:2019-07-31
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure and autoregulation of a P4-ATPase lipid flippase.
Nature, 571, 2019
4CK0
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - FORM 2
Descriptor:DIACYLGLYCEROL KINASE, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ZINC ION, ...
Authors:Li, D., Lyons, J.A., Vogeley, L., Aragao, D., Caffrey, M.
Deposit date:2013-12-23
Release date:2015-01-28
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.924 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase with Zn-Amppcp Bound and its Catalytic Mechanism
To be Published
4N0J
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CRYSTAL STRUCTURE OF DIMETHYLLYSINE HEN EGG-WHITE LYSOZYME IN COMPLEX WITH SCLX4 AT 1.9 A RESOLUTION
Descriptor:Lysozyme C, 25,26,27,28-tetrahydroxypentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-5,11,17,23-tetrasulfonic acid, CHLORIDE ION, ...
Authors:McGovern, R.E., Crowley, P.B.
Deposit date:2013-10-02
Release date:2014-11-12
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural study of a small molecule receptor bound to dimethyllysine in lysozyme.
Chem Sci, 6, 2015
4UXW
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STRUCTURE OF DELTA4-DGKA-APO IN 9.9 MAG
Descriptor:DIACYLGLYCEROL KINASE, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Li, D., Pye, V.E., Aragao, D., Caffrey, M.
Deposit date:2014-08-27
Release date:2015-09-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4UXX
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STRUCTURE OF DELTA4-DGKA WITH AMPPCP IN 9.9 MAG
Descriptor:DIACYLGLYCEROL KINASE, CHLORIDE ION, SODIUM ION, ...
Authors:Li, D., Vogeley, L., Caffrey, M.
Deposit date:2014-08-27
Release date:2015-09-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4UXZ
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STRUCTURE OF DELTA7-DGKA-SYN IN 7.9 MAG TO 2.18 ANGSTROM RESOLUTION
Descriptor:DIACYLGLYCEROL KINASE-DELTA 7, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ...
Authors:Li, D., Howe, N., Caffrey, M.
Deposit date:2014-08-27
Release date:2015-09-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4UYO
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STRUCTURE OF DELTA7-DGKA IN 7.9 MAG BY SERIAL FEMTOSECOND CRYSTATALLOGRAPHY TO 2.18 ANGSTROM RESOLUTION
Descriptor:DIACYLGLYCEROL KINASE-DELTA 7, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ...
Authors:Li, D., Howe, N., Other, O., Caffrey, M.
Deposit date:2014-09-02
Release date:2015-09-30
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015