Author results

1MX7
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TWO HOMOLOGOUS RAT CELLULAR RETINOL-BINDING PROTEINS DIFFER IN LOCAL STRUCTURE AND FLEXIBILITY
Descriptor:CELLULAR RETINOL-BINDING PROTEIN I, APO
Authors:Lu, J., Cistola, D.P., Li, E.
Deposit date:2002-10-01
Release date:2003-07-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Two Homologous Rat Cellular Retinol-binding Proteins Differ in Local Conformational Flexibility.
J.Mol.Biol., 330, 2003
1MX8
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TWO HOMOLOGOUS RAT CELLULAR RETINOL-BINDING PROTEINS DIFFER IN LOCAL STRUCTURE AND FLEXIBILITY
Descriptor:CELLULAR RETINOL-BINDING PROTEIN I, HOLO, RETINOL
Authors:Lu, J., Cistola, D.P., Li, E.
Deposit date:2002-10-01
Release date:2003-07-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Two homologous rat cellular retinol-binding proteins differ in local conformational flexibility.
J.Mol.Biol., 330, 2003
2CJS
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STRUCTURAL BASIS FOR A MUNC13-1 HOMODIMER - MUNC13-1 - RIM HETERODIMER SWITCH: C2-DOMAINS AS VERSATILE PROTEIN-PROTEIN INTERACTION MODULES
Descriptor:UNC-13 HOMOLOG A, REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2, 1,2-ETHANEDIOL, ...
Authors:Lu, J., Machius, M., Dulubova, I., Dai, H., Sudhof, T.C., Tomchick, D.R., Rizo, J.
Deposit date:2006-04-06
Release date:2006-06-07
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural Basis for a Munc13-1 Homodimer to Munc13-1/Rim Heterodimer Switch.
Plos Biol., 4, 2006
2CJT
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STRUCTURAL BASIS FOR A MUNC13-1 HOMODIMER - MUNC13-1 - RIM HETERODIMER SWITCH: C2-DOMAINS AS VERSATILE PROTEIN-PROTEIN INTERACTION MODULES
Descriptor:UNC-13 HOMOLOG A, 1,2-ETHANEDIOL, FORMIC ACID
Authors:Lu, J., Machius, M., Dulubova, I., Dai, H., Sudhof, T.C., Tomchick, D.R., Rizo, J.
Deposit date:2006-04-06
Release date:2006-06-07
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Structural Basis for a Munc13-1 Dimeric to Munc13-1/Rim Heterodimer Switch
Plos Biol., 4, 2006
1EII
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NMR STRUCTURE OF HOLO CELLULAR RETINOL-BINDING PROTEIN II
Descriptor:CELLULAR RETINOL-BINDING PROTEIN II, RETINOL
Authors:Lu, J., Lin, C.L., Tang, C., Ponder, J.W., Kao, J.L., Cistola, D.P., Li, E.
Deposit date:2000-02-25
Release date:2000-08-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Binding of retinol induces changes in rat cellular retinol-binding protein II conformation and backbone dynamics.
J.Mol.Biol., 300, 2000
1KMD
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SOLUTION STRUCTURE OF THE VAM7P PX DOMAIN
Descriptor:Vacuolar morphogenesis protein VAM7
Authors:Lu, J., Garcia, J., Dulubova, I., Sudhof, T.C., Rizo, J.
Deposit date:2001-12-14
Release date:2002-06-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the Vam7p PX domain.
Biochemistry, 41, 2002
5GXO
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DISCOVERY OF A COMPOUND THAT ACTIVATES SIRT3 TO DEACETYLATE MANGANESE SUPEROXIDE DISMUTASE
Descriptor:Superoxide dismutase [Mn], mitochondrial, MANGANESE (II) ION
Authors:Lu, J., Li, J., Wu, M., Wang, J., Xia, Q.
Deposit date:2016-09-19
Release date:2017-08-09
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A small molecule activator of SIRT3 promotes deacetylation and activation of manganese superoxide dismutase.
Free Radic. Biol. Med., 112, 2017
1Z28
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CRYSTAL STRUCTURES OF SULT1A2 AND SULT1A1*3: IMPLICATIONS IN THE BIOACTIVATION OF N-HYDROXY-2-ACETYLAMINO FLUORINE (OH-AAF)
Descriptor:Phenol-sulfating phenol sulfotransferase 1, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Lu, J., Li, H., Liu, M.C., Zhang, J., Li, M., An, X., Chang, W.
Deposit date:2005-03-07
Release date:2006-05-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2.
Biochem.Biophys.Res.Commun., 396, 2010
1Z29
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CRYSTAL STRUCTURES OF SULT1A2 AND SULT1A1*3: IMPLICATIONS IN THE BIOACTIVATION OF N-HYDROXY-2-ACETYLAMINO FLUORINE (OH-AAF)
Descriptor:Phenol-sulfating phenol sulfotransferase 2, CALCIUM ION, ADENOSINE-3'-5'-DIPHOSPHATE, ...
Authors:Lu, J., Li, H., Liu, M.C., Zhang, J., Li, M., An, X., Chang, W.
Deposit date:2005-03-07
Release date:2006-05-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2.
Biochem.Biophys.Res.Commun., 396, 2010
1ZUB
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SOLUTION STRUCTURE OF THE RIM1ALPHA PDZ DOMAIN IN COMPLEX WITH AN ELKS1B C-TERMINAL PEPTIDE
Descriptor:Regulating synaptic membrane exocytosis protein 1, ELKS1b
Authors:Lu, J., Li, H., Wang, Y., Sudhof, T.C., Rizo, J.
Deposit date:2005-05-30
Release date:2005-08-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the RIM1alpha PDZ Domain in Complex with an ELKS1b C-terminal Peptide
J.Mol.Biol., 352, 2005
2G7O
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PROTONATION-MEDIATED STRUCTURAL FLEXIBILITY IN THE F CONJUGATION REGULATORY PROTEIN, TRAM
Descriptor:Protein traM
Authors:Lu, J., Edwards, R.A., Wong, J.J., Manchak, J., Scott, P.G., Frost, L.S., Glover, J.N.
Deposit date:2006-02-28
Release date:2006-06-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM.
Embo J., 25, 2006
2G9E
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PROTONATION-MEDIATED STRUCTURAL FLEXIBILITY IN THE F CONJUGATION REGULATORY PROTEIN, TRAM
Descriptor:Protein traM
Authors:Lu, J., Edwards, R.A., Wong, J.J., Manchak, J., Scott, P.G., Frost, L.S., Glover, J.N.
Deposit date:2006-03-06
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM.
Embo J., 25, 2006
4R3Q
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CRYSTAL STRUCTURE OF SYCE3
Descriptor:Synaptonemal complex central element protein 3
Authors:Lu, J., Feng, J., Zhou, W., Yang, X., Shen, Y.
Deposit date:2014-08-17
Release date:2014-11-26
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Structural insight into the central element assembly of the synaptonemal complex
Sci Rep, 4, 2014
4X4M
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STRUCTURE OF FCGAMMARI IN COMPLEX WITH FC REVEALS THE IMPORTANCE OF GLYCAN RECOGNITION FOR HIGH AFFINITY IGG BINDING
Descriptor:Ig gamma-1 chain C region, High affinity immunoglobulin gamma Fc receptor I, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Lu, J., Sun, P.D.
Deposit date:2014-12-03
Release date:2015-04-08
Method:X-RAY DIFFRACTION (3.485 Å)
Cite:Structure of Fc gamma RI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding.
Proc.Natl.Acad.Sci.USA, 112, 2015
5JQL
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CRYSTAL STRUCTURE OF PHOSPHATIDIC ACID TRANSPORTER UPS1/MDM35 VOID OF BOUND PHOSPHOLIPID FROM SACCHAROMYCES CEREVISIAE AT 2.9 ANGSTROMS RESOLUTION
Descriptor:Protein UPS1, mitochondrial, Mitochondrial distribution and morphology protein 35
Authors:Lu, J., Chan, K.C., Zhai, Y., Fan, J., Sun, F.
Deposit date:2016-05-05
Release date:2017-07-12
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of a phospholipid transport complex
To Be Published
5JQM
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CRYSTAL STRUCTURE OF PHOSPHATIDIC ACID TRANSPORTER UPS1/MDM35 VOID OF BOUND PHOSPHOLIPID FROM SACCHAROMYCES CEREVISIAE AT 1.5 ANGSTROMS RESOLUTION
Descriptor:Protein UPS1, mitochondrial,Mitochondrial distribution and morphology protein 35
Authors:Lu, J., Chan, K.C., Zhai, Y., Fan, J., Sun, F.
Deposit date:2016-05-05
Release date:2017-07-12
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of a phospholipid transport complex
To Be Published
5JQO
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CRYSTAL STRUCTURE OF PHOSPHATIDIC ACID TRANSPORTER UPS1/MDM35 IN COMPLEX WITH (2R)-3-(PHOSPHONOOXY)PROPANE-1,2-DIYL DIHEXANOATE
Descriptor:Mitochondrial distribution and morphology protein 35, Protein UPS1, mitochondrial, ...
Authors:Lu, J., Chan, K.C., Zhai, Y., Fan, J., Sun, F.
Deposit date:2016-05-05
Release date:2017-07-12
Method:X-RAY DIFFRACTION (3.549 Å)
Cite:Structure of a phospholipid transport complex
To Be Published
5TZR
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GPR40 IN COMPLEX WITH PARTIAL AGONIST MK-8666
Descriptor:Free fatty acid receptor 1,Endolysin,Free fatty acid receptor 1, SODIUM ION, (5aR,6S,6aS)-3-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl}methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, ...
Authors:Lu, J., Byrne, N., Patel, S., Sharma, S., Soisson, S.M.
Deposit date:2016-11-22
Release date:2017-06-07
Last modified:2017-07-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40.
Nat. Struct. Mol. Biol., 24, 2017
5TZY
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GPR40 IN COMPLEX WITH AGOPAM AP8 AND PARTIAL AGONIST MK-8666
Descriptor:Free fatty acid receptor 1,Endolysin,Free fatty acid receptor 1, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (5aR,6S,6aS)-3-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl}methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, ...
Authors:Lu, J., Byrne, N., Patel, S., Sharma, S., Soisson, S.M.
Deposit date:2016-11-22
Release date:2017-06-07
Last modified:2017-07-19
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40.
Nat. Struct. Mol. Biol., 24, 2017
6C68
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MHC-INDEPENDENT T CELL RECEPTOR A11
Descriptor:T-cell receptor alpha chain, T-cell receptor beta chain
Authors:Lu, J., Van Laethem, F., Saba, I., Chu, J., Bhattacharya, A., Love, N.C., Tikhonova, A., Radaev, S., Sun, X., Ko, A., Arnon, T., Shifrut, E., Friedman, N., Weng, N., Singer, A., Sun, P.D.
Deposit date:2018-01-18
Release date:2019-01-30
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:MHC-independent t cell receptor A11
To Be Published
1B4M
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NMR STRUCTURE OF APO CELLULAR RETINOL-BINDING PROTEIN II, 24 STRUCTURES
Descriptor:CELLULAR RETINOL-BINDING PROTEIN II
Authors:Lu, J., Lin, C.-L., Tang, C., Ponder, J.W., Kao, J.L.F., Cistola, D.P., Li, E.
Deposit date:1998-12-23
Release date:1999-04-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structure and dynamics of rat apo-cellular retinol-binding protein II in solution: comparison with the X-ray structure.
J.Mol.Biol., 286, 1999
2J1D
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CRYSTALLIZATION OF HDAAM1 C-TERMINAL FRAGMENT
Descriptor:DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 1, PHOSPHATE ION, GLYCEROL
Authors:Lu, J., Meng, W., Poy, F., Eck, M.J.
Deposit date:2006-08-10
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of the Fh2 Domain of Daam1: Implications for Formin Regulation of Actin Assembly.
J.Mol.Biol., 369, 2007
2KCW
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SOLUTION STRUCTURE OF APO-FORM YJAB FROM ESCHERICHIA COLI
Descriptor:Uncharacterized acetyltransferase yjaB
Authors:Lu, J., Wang, X., Jin, C.
Deposit date:2008-12-30
Release date:2009-05-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of Apo-YjaB from Escherichia coli
Proteins, 76, 2009
2RH3
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CRYSTAL STRUCTURE OF PLASMID PTIC58 VIRC2
Descriptor:Protein virC2
Authors:Lu, J., Glover, J.N.M.
Deposit date:2007-10-05
Release date:2008-10-14
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Agrobacterium tumefaciens VirC2 enhances T-DNA transfer and virulence through its C-terminal ribbon-helix-helix DNA-binding fold
Proc.Natl.Acad.Sci.USA, 106, 2009
2U1A
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RNA BINDING DOMAIN 2 OF HUMAN U1A PROTEIN, NMR, 20 STRUCTURES
Descriptor:U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A
Authors:Lu, J., Hall, K.B.
Deposit date:1997-03-26
Release date:1997-09-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Tertiary structure of RBD2 and backbone dynamics of RBD1 and RBD2 of the human U1A protein determined by NMR spectroscopy.
Biochemistry, 36, 1997