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2AOZ
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BU of 2aoz by Molmil
Crystal structure of the myotoxin-II from Atropoides nummifer venom
Descriptor: Phospholipase A2 homolog, SULFATE ION
Authors:Melo, C.C, Murakami, M.T, Angulo, Y, Lomonte, B, Arni, R.K.
Deposit date:2005-08-15
Release date:2006-07-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structure of myotoxin II, a catalytically inactive Lys49 phospholipase A2 homologue from Atropoides nummifer venom.
Acta Crystallogr.,Sect.F, 62, 2006
1Y4L
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BU of 1y4l by Molmil
Crystal structure of Bothrops asper myotoxin II complexed with the anti-trypanosomal drug suramin
Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID, ISOPROPYL ALCOHOL, ...
Authors:Murakami, M.T, Arruda, E.Z, Melo, P.A, Martinez, A.B, Calil-Elias, S, Tomaz, M.A, Lomonte, B, Gutierrez, J.M, Arni, R.K.
Deposit date:2004-12-01
Release date:2005-06-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Inhibition of Myotoxic Activity of Bothrops asper Myotoxin II by the Anti-trypanosomal Drug Suramin.
J.Mol.Biol., 350, 2005
6PWH
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BU of 6pwh by Molmil
Cystal structure of Myotoxin II from Bothrops moojeni co-crystallized with Varespladib (LY315920)
Descriptor: ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid, Basic phospholipase A2 homolog 2, DIMETHYL SULFOXIDE
Authors:Salvador, G.H.M, Fontes, M.R.M.
Deposit date:2019-07-23
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920).
Sci Rep, 9, 2019
8DND
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BU of 8dnd by Molmil
Crystal structure of Bothrops pirajai Piratoxin-I (PrTX-I) and synthetic inhibitor Varespladib (LY315920)
Descriptor: ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid, Basic phospholipase A2 homolog piratoxin-1, SULFATE ION
Authors:Salvador, G.H.M, Fontes, M.R.M.
Deposit date:2022-07-11
Release date:2023-08-02
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.018 Å)
Cite:Structural basis of the myotoxic inhibition of the Bothrops pirajai PrTX-I by the synthetic varespladib.
Biochimie, 207, 2023
5TFV
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BU of 5tfv by Molmil
Crystal Structure of MT-I isolated from Bothrops asper venom.
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Basic phospholipase A2 myotoxin III
Authors:Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M.
Deposit date:2016-09-26
Release date:2017-10-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative "myotoxic cluster".
Biochimie, 133, 2017
7LYE
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BU of 7lye by Molmil
Myotoxin I from Bothrops moojeni co-crystallized with synthetic inhibitor Varespladib (LY315920)
Descriptor: ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Basic phospholipase A2 homolog BomoTx
Authors:Salvador, G.H.M, Borges, R.J, Fontes, M.R.M.
Deposit date:2021-03-06
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.758 Å)
Cite:The synthetic varespladib molecule is a multi-functional inhibitor for PLA 2 and PLA 2 -like ophidic toxins.
Biochim Biophys Acta Gen Subj, 1865, 2021
1PA0
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BU of 1pa0 by Molmil
CRYSTAL STRUCTURE OF BNSP-7, A LYS49-PHOSPHOLIPASE A2
Descriptor: Myotoxic phospholipase A2-like
Authors:Magro, A.J, Soares, A.M, Giglio, J.R, Fontes, M.R.
Deposit date:2003-05-13
Release date:2004-07-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights.
Biochem.Biophys.Res.Commun., 311, 2003
1XXS
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BU of 1xxs by Molmil
Structural insights for fatty acid binding in a Lys49 phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid
Descriptor: Phospholipase A2 homolog 2, STEARIC ACID, SULFATE ION
Authors:Watanabe, L, Soares, A.M, Ward, R.J, Fontes, M.R, Arni, R.K.
Deposit date:2004-11-08
Release date:2005-03-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights for fatty acid binding in a Lys49-phospholipase A(2): crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid
Biochimie, 87, 2005

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