Author results

3CF6
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STRUCTURE OF EPAC2 IN COMPLEX WITH CYCLIC-AMP AND RAP
Descriptor:Rap guanine nucleotide exchange factor (GEF) 4, Ras-related protein Rap-1b, 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, ...
Authors:Rehmann, H., Arias-Palomo, E., Hadders, M.A., Schwede, F., Llorca, O., Bos, J.L.
Deposit date:2008-03-02
Release date:2008-07-29
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B
Nature, 455, 2008
4A5W
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CRYSTAL STRUCTURE OF C5B6
Descriptor:COMPLEMENT C5, COMPLEMENT COMPONENT C6, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Hadders, M.A., Bubeck, D., Forneris, F., Pangburn, M., Llorca, O., Lea, S.M., Gros, P.
Deposit date:2011-10-28
Release date:2012-03-14
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1, 2012
6FO1
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HUMAN R2TP SUBCOMPLEX CONTAINING 1 RUVBL1-RUVBL2 HEXAMER BOUND TO 1 RBD DOMAIN FROM RPAP3.
Descriptor:RuvB-like 1, RuvB-like 2, RNA polymerase II-associated protein 3, ...
Authors:Martino, F., Munoz-Hernandez, H., Rodriguez, C.F., Pearl, L.H., Llorca, O.
Deposit date:2018-02-05
Release date:2018-04-04
Last modified:2018-05-30
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex.
Nat Commun, 9, 2018
6QI8
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TRUNCATED HUMAN R2TP COMPLEX, STRUCTURE 3 (ADP-FILLED)
Descriptor:RuvB-like 1, RuvB-like 2, ADENOSINE-5'-DIPHOSPHATE
Authors:Munoz-Hernandez, H., Rodriguez, C.F., Llorca, O.
Deposit date:2019-01-18
Release date:2019-04-10
Last modified:2019-05-15
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM.
Sci Adv, 5, 2019
6QI9
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TRUNCATED HUMAN R2TP COMPLEX, STRUCTURE 4 (ADP-EMPTY)
Descriptor:RuvB-like 1, RuvB-like 2, ADENOSINE-5'-DIPHOSPHATE
Authors:Munoz-Hernandez, H., Rodriguez, C.F., Llorca, O.
Deposit date:2019-01-18
Release date:2019-05-15
Method:ELECTRON MICROSCOPY (4.63 Å)
Cite:Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM.
Sci Adv, 5, 2019
3C7N
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STRUCTURE OF THE HSP110:HSC70 NUCLEOTIDE EXCHANGE COMPLEX
Descriptor:Heat shock protein homolog SSE1, Heat shock cognate, MAGNESIUM ION, ...
Authors:Schuermann, J.P., Jiang, J., Hart, P.J., Sousa, R.
Deposit date:2008-02-07
Release date:2008-05-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.115 Å)
Cite:Structure of the Hsp110:Hsc70 nucleotide exchange machine
Mol.Cell, 31, 2008
3DKX
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CRYSTAL STRUCTURE OF THE REPLICATION INITIATOR PROTEIN ENCODED ON PLASMID PMV158 (REPB), TRIGONAL FORM, TO 2.7 ANG RESOLUTION
Descriptor:Replication protein repB, MANGANESE (II) ION, CHLORIDE ION, ...
Authors:Boer, D.R., Ruiz-Maso, J.A., Blanco, A.G., Vives-Llacer, M., Uson, I., Gomis-Ruth, F.X., Espinosa, M., Del Solar, G., Coll, M.
Deposit date:2008-06-26
Release date:2009-06-30
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains
Embo J., 28, 2009
3DKY
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CRYSTAL STRUCTURE OF THE REPLICATION INITIATOR PROTEIN ENCODED ON PLASMID PMV158 (REPB), TETRAGONAL FORM, TO 3.6 ANG RESOLUTION
Descriptor:Replication protein repB, MANGANESE (II) ION
Authors:Boer, D.R., Ruiz-Maso, J.A., Blanco, A.G., Vives-Llacer, M., Uson, I., Gomis-Ruth, F.X., Espinosa, M., Del Solar, G., Coll, M.
Deposit date:2008-06-26
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains
Embo J., 28, 2009
3FLO
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CRYSTAL STRUCTURE OF THE CARBOXYL-TERMINAL DOMAIN OF YEAST DNA POLYMERASE ALPHA IN COMPLEX WITH ITS B SUBUNIT
Descriptor:DNA polymerase alpha subunit B, DNA polymerase alpha catalytic subunit A, SULFATE ION, ...
Authors:Klinge, S.N., Pellegrini, L.
Deposit date:2008-12-19
Release date:2009-06-09
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:3D architecture of DNA Pol alpha reveals the functional core of multi-subunit replicative polymerases
Embo J., 28, 2009
4A0P
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CRYSTAL STRUCTURE OF LRP6P3E3P4E4
Descriptor:LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Chen, S., Malinauskas, T., Aricescu, A.R., Siebold, C., Jones, E.Y.
Deposit date:2011-09-11
Release date:2011-10-26
Last modified:2012-01-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Studies of Lrp6 Ectodomain Reveal a Platform for Wnt Signaling.
Dev.Cell, 21, 2011
4IS4
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THE GLUTAMINE SYNTHETASE FROM THE DICOTYLEDONOUS PLANT M. TRUNCATULA IS A DECAMER
Descriptor:Glutamine synthetase
Authors:Seabra, A.R., Carvalho, H., Pereira, P.J.B.
Deposit date:2013-01-16
Release date:2014-04-09
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The structures of cytosolic and plastid-located glutamine synthetases from Medicago truncatula reveal a common and dynamic architecture.
Acta Crystallogr.,Sect.D, 70, 2014
1C1Y
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CRYSTAL STRUCTURE OF RAP.GMPPNP IN COMPLEX WITH THE RAS-BINDING-DOMAIN OF C-RAF1 KINASE (RAFRBD).
Descriptor:RAS-RELATED PROTEIN RAP-1A, PROTO-ONCOGENE SERINE/THREONINE PROTEIN KINASE RAF-1, MAGNESIUM ION, ...
Authors:Nassar, N.
Deposit date:1999-07-22
Release date:1999-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue.
Nature, 375, 1995