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8Q62
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BU of 8q62 by Molmil
Early closed conformation of the g-tubulin ring complex
Descriptor: Gamma-tubulin complex component 2, Gamma-tubulin complex component 3, Gamma-tubulin complex component 4, ...
Authors:Llorca, O, Serna, M, Fernandez-Leiro, R.
Deposit date:2023-08-10
Release date:2024-02-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Transition of human gamma-tubulin ring complex into a closed conformation during microtubule nucleation.
Science, 383, 2024
7P6X
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BU of 7p6x by Molmil
Cryo-Em structure of the hexameric RUVBL1-RUVBL2 in complex with ZNHIT2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Llorca, O, Serna, M, Fernandez-Leiro, R.
Deposit date:2021-07-18
Release date:2021-12-15
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8.
Nucleic Acids Res., 50, 2022
8AG4
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BU of 8ag4 by Molmil
Vaccinia C16 protein bound to Ku70/Ku80
Descriptor: Protein C10, X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6
Authors:Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O.
Deposit date:2022-07-19
Release date:2022-11-09
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (2.46 Å)
Cite:Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
8AG3
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BU of 8ag3 by Molmil
Vaccinia C16 N-terminal domains
Descriptor: Protein C10
Authors:Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O.
Deposit date:2022-07-19
Release date:2022-11-09
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
8AG5
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BU of 8ag5 by Molmil
Vaccinia C16 protein bound to Ku70/Ku80
Descriptor: Ku70-Xrcc6, Protein C10, X-ray repair cross-complementing protein 5
Authors:Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O.
Deposit date:2022-07-19
Release date:2022-11-09
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
6FO1
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BU of 6fo1 by Molmil
Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 RBD domain from RPAP3.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RNA polymerase II-associated protein 3, RuvB-like 1, ...
Authors:Martino, F, Munoz-Hernandez, H, Rodriguez, C.F, Pearl, L.H, Llorca, O.
Deposit date:2018-02-05
Release date:2018-04-04
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex.
Nat Commun, 9, 2018
7OLE
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BU of 7ole by Molmil
Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2, ...
Authors:Pal, M, Llorca, O, Pearl, L.
Deposit date:2021-05-19
Release date:2021-07-07
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone.
Cell Rep, 36, 2021
7B00
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BU of 7b00 by Molmil
Human LAT2-4F2hc complex in the apo-state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Digitonin, Isoform 2 of 4F2 cell-surface antigen heavy chain, ...
Authors:Rodriguez, C.F, Escudero-Bravo, P, Garcia-Martin, C, Boskovic, J, Errasti-Murugarren, E, Palacin, M, Llorca, O.
Deposit date:2020-11-17
Release date:2021-10-27
Last modified:2022-02-23
Method:ELECTRON MICROSCOPY (3.98 Å)
Cite:Structural basis for substrate specificity of heteromeric transporters of neutral amino acids.
Proc Natl Acad Sci U S A, 118, 2021
6QI9
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BU of 6qi9 by Molmil
Truncated human R2TP complex, structure 4 (ADP-empty)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O.
Deposit date:2019-01-18
Release date:2019-05-15
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.63 Å)
Cite:Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM.
Sci Adv, 5, 2019
6QI8
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BU of 6qi8 by Molmil
Truncated human R2TP complex, structure 3 (ADP-filled)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O.
Deposit date:2019-01-18
Release date:2019-04-10
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM.
Sci Adv, 5, 2019
4A5W
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BU of 4a5w by Molmil
Crystal structure of C5b6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C5, ...
Authors:Hadders, M.A, Bubeck, D, Forneris, F, Pangburn, M, Llorca, O, Lea, S.M, Gros, P.
Deposit date:2011-10-28
Release date:2012-03-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1, 2012
7AHO
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BU of 7aho by Molmil
RUVBL1-RUVBL2 heterohexameric ring after binding of RNA helicase DHX34
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Lopez-Perrote, A, Rodriguez, C.F, Llorca, O.
Deposit date:2020-09-25
Release date:2020-11-25
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM.
Elife, 9, 2020
7AS4
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BU of 7as4 by Molmil
Recombinant human gTuRC
Descriptor: Actin, cytoplasmic 1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Serna, M, Fernandez-Leiro, R, Llorca, O.
Deposit date:2020-10-26
Release date:2021-01-20
Method:ELECTRON MICROSCOPY (4.13 Å)
Cite:Assembly of the asymmetric human gamma-tubulin ring complex by RUVBL1-RUVBL2 AAA ATPase.
Sci Adv, 6, 2020
6SGX
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BU of 6sgx by Molmil
Structure of protomer 1 of the ESX-3 core complex
Descriptor: ESX-3 secretion system EccB3, ESX-3 secretion system protein EccC3, ESX-3 secretion system protein EccD3, ...
Authors:Famelis, N, Rivera-Calzada, A, Llorca, O, Geibel, S.
Deposit date:2019-08-05
Release date:2019-10-09
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Architecture of the mycobacterial type VII secretion system.
Nature, 576, 2019
6SGY
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BU of 6sgy by Molmil
Structure of EccB3 dimer from the ESX-3 core complex
Descriptor: ESX-3 secretion system protein EccB3
Authors:Famelis, N, Rivera-Calzada, A, Llorca, O, Geibel, S.
Deposit date:2019-08-05
Release date:2019-10-09
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Architecture of the mycobacterial type VII secretion system.
Nature, 576, 2019
6SGW
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BU of 6sgw by Molmil
Structure of the ESX-3 core complex
Descriptor: ESX-3 secretion system ATPase EccB3, ESX-3 secretion system protein EccC3, ESX-3 secretion system protein EccD3, ...
Authors:Famelis, N, Rivera-Calzada, A, Llorca, O, Geibel, S.
Deposit date:2019-08-05
Release date:2019-10-09
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Architecture of the mycobacterial type VII secretion system.
Nature, 576, 2019
6SGZ
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BU of 6sgz by Molmil
Structure of protomer 2 of the ESX-3 core complex
Descriptor: ESX-3 secretion system ATPase EccB3, ESX-3 secretion system protein EccC3, ESX-3 secretion system protein EccD3, ...
Authors:Famelis, N, Rivera-Calzada, A, Llorca, O, Geibel, S.
Deposit date:2019-08-05
Release date:2019-10-09
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Architecture of the mycobacterial type VII secretion system.
Nature, 576, 2019
3CF6
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BU of 3cf6 by Molmil
Structure of Epac2 in complex with cyclic-AMP and Rap
Descriptor: 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, Rap guanine nucleotide exchange factor (GEF) 4, Ras-related protein Rap-1b, ...
Authors:Rehmann, H, Arias-Palomo, E, Hadders, M.A, Schwede, F, Llorca, O, Bos, J.L.
Deposit date:2008-03-02
Release date:2008-07-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B
Nature, 455, 2008
4IS4
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BU of 4is4 by Molmil
The glutamine synthetase from the dicotyledonous plant M. truncatula is a decamer
Descriptor: Glutamine synthetase
Authors:Seabra, A.R, Carvalho, H, Pereira, P.J.B.
Deposit date:2013-01-16
Release date:2014-04-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The structures of cytosolic and plastid-located glutamine synthetases from Medicago truncatula reveal a common and dynamic architecture.
Acta Crystallogr.,Sect.D, 70, 2014
1C1Y
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BU of 1c1y by Molmil
CRYSTAL STRUCTURE OF RAP.GMPPNP IN COMPLEX WITH THE RAS-BINDING-DOMAIN OF C-RAF1 KINASE (RAFRBD).
Descriptor: CALCIUM ION, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nassar, N.
Deposit date:1999-07-22
Release date:1999-08-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue.
Nature, 375, 1995
4A0P
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BU of 4a0p by Molmil
Crystal structure of LRP6P3E3P4E4
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chen, S, Malinauskas, T, Aricescu, A.R, Siebold, C, Jones, E.Y.
Deposit date:2011-09-11
Release date:2011-10-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Studies of Lrp6 Ectodomain Reveal a Platform for Wnt Signaling.
Dev.Cell, 21, 2011
3C7N
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BU of 3c7n by Molmil
Structure of the Hsp110:Hsc70 Nucleotide Exchange Complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, ...
Authors:Schuermann, J.P, Jiang, J, Hart, P.J, Sousa, R.
Deposit date:2008-02-07
Release date:2008-05-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.115 Å)
Cite:Structure of the Hsp110:Hsc70 nucleotide exchange machine
Mol.Cell, 31, 2008
6TY3
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BU of 6ty3 by Molmil
FAK structure from single particle analysis of 2D crystals
Descriptor: Focal adhesion kinase 1
Authors:Acebron, I, Righetto, R, Biyani, N, Chami, M, Boskovic, J, Stahlberg, H, Lietha, D.
Deposit date:2020-01-15
Release date:2020-08-19
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (6.32 Å)
Cite:Structural basis of Focal Adhesion Kinase activation on lipid membranes.
Embo J., 39, 2020
6TY4
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BU of 6ty4 by Molmil
FAK structure with AMP-PNP from single particle analysis of 2D crystals
Descriptor: Focal adhesion kinase 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Acebron, I, Righetto, R, Biyani, N, Chami, M, Boskovic, J, Stahlberg, H, Lietha, D.
Deposit date:2020-01-15
Release date:2020-08-19
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (5.96 Å)
Cite:Structural basis of Focal Adhesion Kinase activation on lipid membranes.
Embo J., 39, 2020
3DKX
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BU of 3dkx by Molmil
Crystal Structure of the replication initiator protein encoded on plasmid pMV158 (RepB), trigonal form, to 2.7 Ang resolution
Descriptor: CHLORIDE ION, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Boer, D.R, Ruiz-Maso, J.A, Blanco, A.G, Vives-Llacer, M, Uson, I, Gomis-Ruth, F.X, Espinosa, M, Del Solar, G, Coll, M.
Deposit date:2008-06-26
Release date:2009-06-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains
Embo J., 28, 2009

 

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