7B00

Human LAT2-4F2hc complex in the apo-state

Summary for 7B00

Entry DOI	10.2210/pdb7b00/pdb
EMDB information	11952
Descriptor	Large neutral amino acids transporter small subunit 2, Isoform 2 of 4F2 cell-surface antigen heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	hats, amino-acid, transporter, membrane, protein, heterodimer, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	119350.70
Authors	Rodriguez, C.F.,Escudero-Bravo, P.,Garcia-Martin, C.,Boskovic, J.,Errasti-Murugarren, E.,Palacin, M.,Llorca, O. (deposition date: 2020-11-17, release date: 2021-10-27, Last modification date: 2022-02-23)
Primary citation	Rodriguez, C.F.,Escudero-Bravo, P.,Diaz, L.,Bartoccioni, P.,Garcia-Martin, C.,Gilabert, J.G.,Boskovic, J.,Guallar, V.,Errasti-Murugarren, E.,Llorca, O.,Palacin, M. Structural basis for substrate specificity of heteromeric transporters of neutral amino acids. Proc Natl Acad Sci U S A, 118:-, 2021 Cited by PubMed: 34848541 DOI: 10.1073/pnas.2113573118 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.98 Å)

Structure validation