5ZHP | | M3 MUSCARINIC ACETYLCHOLINE RECEPTOR IN COMPLEX WITH A SELECTIVE ANTAGONIST | | Descriptor: | Muscarinic acetylcholine receptor M3,Endolysin,Endolysin,Muscarinic acetylcholine receptor M3, TETRAETHYLENE GLYCOL, MALTOSE, ... | | Authors: | Liu, H., Hofmann, J., Fish, I., Schaake, B., Eitel, K., Bartuschat, A., Kaindl, J., Rampp, H., Banerjee, A., Hubner, H., Clark, M.J., Vincent, S.G., Fisher, J., Heinrich, M., Hirata, K., Liu, X., Sunahara, R.K., Shoichet, B.K., Kobilka, B.K., Gmeiner, P. | | Deposit date: | 2018-03-13 | | Release date: | 2018-11-28 | | Last modified: | 2018-12-05 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
5ET0 | | CRYSTAL STRUCTURE OF MYO3B-ARB2 IN COMPLEX WITH ESPIN1-AR | | Descriptor: | Espin, Myosin-IIIb | | Authors: | Liu, H., Li, J., Liu, W., Zhang, M. | | Deposit date: | 2015-11-17 | | Release date: | 2016-02-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin
Elife, 5, 2016
|
|
5ET1 | | CRYSTAL STRUCTURE OF MYO3B-ARB1 IN COMPLEX WITH ESPIN1-AR | | Descriptor: | Espin, Myosin-IIIb, GLYCEROL | | Authors: | Liu, H., Li, J., liu, W., Zhang, M. | | Deposit date: | 2015-11-17 | | Release date: | 2016-02-03 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin
Elife, 5, 2016
|
|
3CYV | |
4EXN | | CRYSTAL STRUCTURE OF MOUSE INTERLEUKIN-34 | | Descriptor: | Interleukin-34, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... | | Authors: | Liu, H., Leo, C., Chen, X., Wong, B.R., Williams, L.T., Lin, H., He, X. | | Deposit date: | 2012-04-30 | | Release date: | 2012-05-30 | | Last modified: | 2012-06-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Biochim.Biophys.Acta, 1824, 2012
|
|
4EXP | | STRUCTURE OF MOUSE INTERLEUKIN-34 IN COMPLEX WITH MOUSE FMS | | Descriptor: | Interleukin-34, Macrophage colony-stimulating factor 1 receptor, N-ACETYL-D-GLUCOSAMINE | | Authors: | Liu, H., Leo, C., Chen, X., Wong, B.R., Williams, L.T., Lin, H., He, X. | | Deposit date: | 2012-04-30 | | Release date: | 2012-05-30 | | Last modified: | 2012-06-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Biochim.Biophys.Acta, 1824, 2012
|
|
4FI1 | | CRYSTAL STRUCTURE OF SCCK2 ALPHA IN COMPLEX WITH ATP | | Descriptor: | Casein kinase II subunit alpha, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Liu, H., Wang, H., Teng, M., Li, X. | | Deposit date: | 2012-06-07 | | Release date: | 2013-06-19 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Crystal structure of scCK2 alpha in complex with ATP
To be Published
|
|
4JQE | | CRYSTAL STRUCTURE OF SCCK2 ALPHA IN COMPLEX WITH AMPPN | | Descriptor: | Casein kinase II subunit alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Liu, H. | | Deposit date: | 2013-03-20 | | Release date: | 2014-03-05 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
4JR7 | | CRYSTAL STRUCTURE OF SCCK2 ALPHA IN COMPLEX WITH GMPPNP | | Descriptor: | Casein kinase II subunit alpha, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION | | Authors: | Liu, H. | | Deposit date: | 2013-03-21 | | Release date: | 2014-03-05 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
4LFI | | CRYSTAL STRUCTURE OF SCCK2 ALPHA IN COMPLEX WITH GMPPNP | | Descriptor: | Casein kinase II subunit alpha, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MANGANESE (II) ION, ... | | Authors: | Liu, H. | | Deposit date: | 2013-06-27 | | Release date: | 2014-03-05 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
4MWH | | CRYSTAL STRUCTURE OF SCCK2 ALPHA IN COMPLEX WITH ATP | | Descriptor: | Casein kinase II subunit alpha, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Liu, H. | | Deposit date: | 2013-09-24 | | Release date: | 2013-11-20 | | Last modified: | 2014-03-05 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
6C1Q | | CRYSTAL STRUCTURE OF HUMAN C5A RECEPTOR IN COMPLEX WITH AN ORTHOSTERIC ANTAGONIST PMX53 AND AN ALLOSTERIC ANTAGONIST NDT9513727 | | Descriptor: | Soluble cytochrome b562, C5a anaphylatoxin chemotactic receptor 1 chimera, PMX53, ... | | Authors: | Liu, H., Wang, L., Wei, Z., Zhang, C. | | Deposit date: | 2018-01-05 | | Release date: | 2018-05-30 | | Last modified: | 2020-01-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Orthosteric and allosteric action of the C5a receptor antagonists.
Nat. Struct. Mol. Biol., 25, 2018
|
|
6C1R | | CRYSTAL STRUCTURE OF HUMAN C5A RECEPTOR IN COMPLEX WITH AN ORTHOSTERIC ANTAGONIST PMX53 AND AN ALLOSTERIC ANTAGONIST AVACOPAN | | Descriptor: | Soluble cytochrome b562, C5a anaphylatoxin chemotactic receptor 1 chimera, PMX53, ... | | Authors: | Liu, H., Wang, L., Wei, Z., Zhang, C. | | Deposit date: | 2018-01-05 | | Release date: | 2018-05-30 | | Last modified: | 2020-01-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Orthosteric and allosteric action of the C5a receptor antagonists.
Nat. Struct. Mol. Biol., 25, 2018
|
|
1MY9 | | SOLUTION STRUCTURE OF A K+ CATION STABILIZED DIMERIC RNA QUADRUPLEX CONTAINING TWO G:G(:A):G:G(:A) HEXADS, G:G:G:G TETRADS AND UUUU LOOPS | | Descriptor: | 5'-R(*GP*GP*AP*GP*GP*UP*UP*UP*UP*GP*GP*AP*GP*G)-3' | | Authors: | Liu, H., Matsugami, A., Katahira, M., Uesugi, S. | | Deposit date: | 2002-10-04 | | Release date: | 2003-10-07 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | A Dimeric RNA Quadruplex Architecture Comprised of Two G:G(:A):G:G(:A) Hexads, G:G:G:G Tetrads and UUUU Loops
J.Mol.Biol., 322, 2002
|
|
2JBM | | QPRTASE STRUCTURE FROM HUMAN | | Descriptor: | NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE, S,R MESO-TARTARIC ACID | | Authors: | Liu, H., Naismith, J.H. | | Deposit date: | 2006-12-08 | | Release date: | 2007-11-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and Kinetic Characterization of Quinolinate Phosphoribosyltransferase (Hqprtase) from Homo Sapiens.
J.Mol.Biol., 373, 2007
|
|
2O26 | | STRUCTURE OF A CLASS III RTK SIGNALING ASSEMBLY | | Descriptor: | Kit ligand, Mast/stem cell growth factor receptor, BETA-L-FUCOSE, ... | | Authors: | Liu, H., Chen, X., Focia, P.J., He, X. | | Deposit date: | 2006-11-29 | | Release date: | 2007-03-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases.
Embo J., 26, 2007
|
|
2O27 | |
3G5C | | STRUCTURAL AND BIOCHEMICAL STUDIES ON THE ECTODOMAIN OF HUMAN ADAM22 | | Descriptor: | ADAM 22, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION | | Authors: | Liu, H., Shim, A., Chen, X., He, X. | | Deposit date: | 2009-02-04 | | Release date: | 2009-08-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Structural and biochemical studies on the ectodomain of human ADAM22
J.Biol.Chem., 2009
|
|
3IZO | |
3JA4 | |
3JA5 | |
3NVN | | MOLECULAR MECHANISM OF GUIDANCE CUE RECOGNITION | | Descriptor: | EVM139, Plexin-C1, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ... | | Authors: | Liu, H., Juo, Z., Shim, A., Focia, P., Chen, X., Garcia, C., He, X. | | Deposit date: | 2010-07-08 | | Release date: | 2010-09-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Structural Basis of Semaphorin-Plexin Recognition and Viral Mimicry from Sema7A and A39R Complexes with PlexinC1.
Cell(Cambridge,Mass.), 142, 2010
|
|
3NVX | | MOLECULAR MECHANISM OF GUIDANCE CUE RECOGNITION | | Descriptor: | Protein A39, N-ACETYL-D-GLUCOSAMINE | | Authors: | Liu, H., Juo, Z., Shim, A., Focia, P., Chen, X., Garcia, C., He, X. | | Deposit date: | 2010-07-08 | | Release date: | 2010-09-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis of Semaphorin-Plexin Recognition and Viral Mimicry from Sema7A and A39R Complexes with PlexinC1.
Cell(Cambridge,Mass.), 142, 2010
|
|
3P3Y | |
3P40 | |
