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5F59
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THE CRYSTAL STRUCTURE OF MLL3 SET DOMAIN
分子名称:Histone-lysine N-methyltransferase 2C, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE
著者Li, Y., Lei, M., Chen, Y.
登録日2015-12-04
公開日2016-02-24
最終更新日2016-04-20
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F5E
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THE CRYSTAL STRUCTURE OF MLL1 SET DOMAIN WITH N3816I/Q3867L MUTATION
分子名称:Histone-lysine N-methyltransferase 2A, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE
著者Li, Y., Lei, M., Chen, Y.
登録日2015-12-04
公開日2016-02-24
最終更新日2016-04-20
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F6K
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CRYSTAL STRUCTURE OF THE MLL3-ASH2L-RBBP5 COMPLEX
分子名称:Set1/Ash2 histone methyltransferase complex subunit ASH2,Set1/Ash2 histone methyltransferase complex subunit ASH2, Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, ...
著者Li, Y., Lei, M., Chen, Y.
登録日2015-12-06
公開日2016-02-24
最終更新日2016-04-20
実験手法X-RAY DIFFRACTION (2.411 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F6L
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THE CRYSTAL STRUCTURE OF MLL1 (N3861I/Q3867L) IN COMPLEX WITH RBBP5 AND ASH2L
分子名称:Retinoblastoma-binding protein 5, Set1/Ash2 histone methyltransferase complex subunit ASH2, Histone-lysine N-methyltransferase 2A, ...
著者Li, Y., Lei, M., Chen, Y.
登録日2015-12-06
公開日2016-02-24
最終更新日2016-04-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
1HQR
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CRYSTAL STRUCTURE OF A SUPERANTIGEN BOUND TO THE HIGH-AFFINITY, ZINC-DEPENDENT SITE ON MHC CLASS II
分子名称:HLA-DR ALPHA CHAIN, HLA-DR BETA CHAIN, MYELIN BASIC PROTEIN, ...
著者Li, Y., Li, H., Dimasi, N., Schlievert, P., Mariuzza, R.
登録日2000-12-19
公開日2001-01-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II.
Immunity, 14, 2001
2N7G
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STRUCTURE OF THE CYCLIC NUCLEOTIDE-BINDING HOMOLOGY DOMAIN OF THE HERG CHANNEL
分子名称:Potassium voltage-gated channel subfamily H member 2
著者Li, Y., Ng, H., Li, Q., Kang, C.
登録日2015-09-10
公開日2016-05-18
実験手法SOLUTION NMR
主引用文献Structure of the Cyclic Nucleotide-Binding Homology Domain of the hERG Channel and Its Insight into Type 2 Long QT Syndrome
Sci Rep, 6, 2016
2N7Q
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STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF HUMAN NICASTRIN IN SDS MICELLES
分子名称:Nicastrin
著者Li, Y., Liew, L., Li, Q., Kang, C.
登録日2015-09-17
公開日2016-04-27
実験手法SOLUTION NMR
主引用文献Structure of the transmembrane domain of human nicastrin-a component of gamma-secretase
Sci Rep, 6, 2016
2N7R
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STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF HUMAN NICASTRIN IN DPC MICELLES
分子名称:Nicastrin
著者Li, Y., Liew, L., Li, Q., Kang, C.
登録日2015-09-17
公開日2016-04-27
実験手法SOLUTION NMR
主引用文献Structure of the transmembrane domain of human nicastrin-a component of gamma-secretase
Sci Rep, 6, 2016
4P5A
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CRYSTAL STRUCTURE OF A UMP/DUMP METHYLASE POLB FROM STREPTOMYCES CACAOI BOUND WITH 5-BR UMP
分子名称:Thymidylate synthase ThyX, FLAVIN-ADENINE DINUCLEOTIDE, 5-BROMO-URIDINE-5'-MONOPHOSPHATE
著者Li, Y., Chen, W., Li, J., Xia, Z., Deng, Z., Zhou, J.
登録日2014-03-15
公開日2015-12-09
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi with 5-Br UMP
To Be Published
4P5B
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CRYSTAL STRUCTURE OF A UMP/DUMP METHYLASE POLB FROM STREPTOMYCES CACAOI BOUND WITH 5-BR DUMP
分子名称:Thymidylate synthase ThyX, FLAVIN-ADENINE DINUCLEOTIDE, 5-BROMO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, ...
著者Li, Y., Chen, W., Li, J., Xia, Z., Deng, Z., Zhou, J.
登録日2014-03-15
公開日2015-12-09
実験手法X-RAY DIFFRACTION (2.274 Å)
主引用文献Crystal structure of a UMP/dUMP methylase PolB form Streptomyces cacaoi bound with 5-Br dUMP
To Be Published
5ZN9
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CRYSTAL STRUCTURE OF PX DOMAIN
分子名称:Sorting nexin-27, SULFATE ION
著者Li, Y., Zhu, Z., Li, F., Liao, S., Xu, C.
登録日2018-04-08
公開日2019-04-10
実験手法X-RAY DIFFRACTION (1.776 Å)
主引用文献Crystal structure of PX domain
To Be Published
1XGR
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STRUCTURE FOR ANTIBODY HYHEL-63 Y33I MUTANT COMPLEXED WITH HEN EGG LYSOZYME
分子名称:antibody kappa light chain, antibody kappa heavy chain, Lysozyme C
著者Li, Y., Huang, Y., Swaminathan, C.P., Smith-Gill, S.J., Mariuzza, R.A.
登録日2004-09-17
公開日2005-09-06
最終更新日2013-10-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces
Structure, 13, 2005
1XGU
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STRUCTURE FOR ANTIBODY HYHEL-63 Y33F MUTANT COMPLEXED WITH HEN EGG LYSOZYME
分子名称:antibody kappa light chain, antibody kappa heavy chain, Lysozyme C
著者Li, Y., Huang, Y., Swaminathan, C.P., Smith-Gill, S.J., Mariuzza, R.A.
登録日2004-09-17
公開日2005-09-06
最終更新日2013-10-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces
Structure, 13, 2005
3ETL
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RADA RECOMBINASE FROM METHANOCOCCUS MARIPALUDIS IN COMPLEX WITH AMPPNP
分子名称:DNA repair and recombination protein radA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION
著者Li, Y., He, Y., Luo, Y.
登録日2008-10-08
公開日2009-05-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis.
Acta Crystallogr.,Sect.D, 65, 2009
3EW9
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RADA RECOMBINASE FROM METHANOCOCCUS MARIPALUDIS IN COMPLEX WITH AMPPNP AND POTASSIUM IONS
分子名称:DNA repair and recombination protein radA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
著者Li, Y., He, Y., Luo, Y.
登録日2008-10-14
公開日2009-05-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis.
Acta Crystallogr.,Sect.D, 65, 2009
3EWA
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RADA RECOMBINASE FROM METHANOCOCCUS MARIPALUDIS IN COMPLEX WITH AMPPNP AND AMMONIUM IONS
分子名称:DNA repair and recombination protein radA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION
著者Li, Y., He, Y., Luo, Y.
登録日2008-10-14
公開日2009-05-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis.
Acta Crystallogr.,Sect.D, 65, 2009
3FYH
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RECOMBINASE IN COMPLEX WITH ADP AND METATUNGSTATE
分子名称:DNA repair and recombination protein radA, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Li, Y., He, Y., Luo, Y.
登録日2009-01-22
公開日2009-09-01
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of an archaeal Rad51 homologue in complex with a metatungstate inhibitor.
Biochemistry, 48, 2009
5DO2
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COMPLEX STRUCTURE OF MERS-RBD BOUND WITH 4C2 ANTIBODY
分子名称:S protein, 4C2 heavy chain, 4C2 light chain, ...
著者Li, Y., Wan, Y., Liu, P., Zhao, J., Lu, G., Qi, J., Wang, Q., Lu, X., Wu, Y., Liu, W., Yuen, K.Y., Perlman, S., Gao, G.F., Yan, J.
登録日2015-09-10
公開日2015-10-14
最終更新日2015-11-11
実験手法X-RAY DIFFRACTION (2.409 Å)
主引用文献A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein.
Cell Res., 25, 2015
6A3V
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COMPLEX STRUCTURE OF HUMAN 4-1BB AND 4-1BBL
分子名称:Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9, N-ACETYL-D-GLUCOSAMINE
著者Li, Y., Zhang, C., Chai, Y., Qi, J., Tien, P., Gao, S., Gao, G.F.
登録日2018-06-17
公開日2018-10-10
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (3.391 Å)
主引用文献Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.
Cell Rep, 25, 2018
6A3W
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COMPLEX STRUCTURE OF 4-1BB AND UTOMILUMAB
分子名称:utomilumab VH, utomilumab VL, Tumor necrosis factor receptor superfamily member 9, ...
著者Li, Y., Tan, S., Zhang, C., Chai, Y., Qi, J., Tien, P., Gao, S., Gao, G.F.
登録日2018-06-17
公開日2018-10-10
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.
Cell Rep, 25, 2018
1XGP
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STRUCTURE FOR ANTIBODY HYHEL-63 Y33A MUTANT COMPLEXED WITH HEN EGG LYSOZYME
分子名称:antibody kappa light chain, antibody kappa heavy chain, Lysozyme C
著者Li, Y., Mariuzza, R.A.
登録日2004-09-17
公開日2005-09-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces
Structure, 13, 2005
1XGQ
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STRUCTURE FOR ANTIBODY HYHEL-63 Y33V MUTANT COMPLEXED WITH HEN EGG LYSOZYME
分子名称:antibody kappa light chain, antibody kappa heavy chain, Lysozyme C
著者Li, Y., Mariuzza, R.A.
登録日2004-09-17
公開日2005-09-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces
Structure, 13, 2005
1XGT
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STRUCTURE FOR ANTIBODY HYHEL-63 Y33L MUTANT COMPLEXED WITH HEN EGG LYSOZYME
分子名称:antibody kappa light chain, antibody kappa heavy chain, Lysozyme C
著者Li, Y., Mariuzza, R.A.
登録日2004-09-17
公開日2005-09-06
最終更新日2013-10-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces
Structure, 13, 2005
1ZGL
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CRYSTAL STRUCTURE OF 3A6 TCR BOUND TO MBP/HLA-DR2A
分子名称:HLA class II histocompatibility antigen, DR alpha chain, major histocompatibility complex, ...
著者Li, Y., Huang, Y., Lue, J., Quandt, J.A., Martin, R., Mariuzza, R.A.
登録日2005-04-21
公開日2005-10-18
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule.
Embo J., 24, 2005
2M19
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SOLUTION STRUCTURE OF THE HALOFERAX VOLCANII HVO 2177 PROTEIN
分子名称:Molybdopterin converting factor subunit 1
著者Li, Y., Maciejewski, M.W., Martin, J., Jin, K., Zhang, Y., Lu, M., Maupin-Furlow, J.A., Hao, B.
登録日2012-11-21
公開日2013-08-07
最終更新日2013-10-02
実験手法SOLUTION NMR
主引用文献Crystal structure of the ubiquitin-like small archaeal modifier protein 2 from Haloferax volcanii.
Protein Sci., 22, 2013