Author results

5KUE
  • Download 5kue
  • View 5kue
Molmil generated image of 5kue
HUMAN SEMET INCORPORATED I141M/L146M MITOCHONDRIAL CALCIUM UNIPORTER (RESIDUES 72-189) CRYSTAL STRUCTURE WITH MAGNESIUM
Descriptor:Calcium uniporter protein, mitochondrial, MAGNESIUM ION, ...
Authors:Mok, C.Y.M., Lee, S.K., Junop, M.S., Stathopulos, P.B.
Deposit date:2016-07-13
Release date:2016-09-07
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations.
Cell Chem Biol, 23, 2016
5KUG
  • Download 5kug
  • View 5kug
Molmil generated image of 5kug
HUMAN MITOCHONDRIAL CALCIUM UNIPORTER (RESIDUES 72-189) CRYSTAL STRUCTURE WITH LITHIUM
Descriptor:Calcium uniporter protein, mitochondrial
Authors:Mok, M.C.Y., Lee, S.K., Junop, M.S., Stathopulos, P.B.
Deposit date:2016-07-13
Release date:2016-09-07
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations.
Cell Chem Biol, 23, 2016
5KUI
  • Download 5kui
  • View 5kui
Molmil generated image of 5kui
HUMAN MITOCHONDRIAL CALCIUM UNIPORTER (RESIDUES 72-189) CRYSTAL STRUCTURE WITH CALCIUM.
Descriptor:Calcium uniporter protein, mitochondrial
Authors:Mok, M.C.Y., Lee, S.K., Junop, M.S., Stathopulos, P.B.
Deposit date:2016-07-13
Release date:2016-09-07
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations.
Cell Chem Biol, 23, 2016
5KUJ
  • Download 5kuj
  • View 5kuj
Molmil generated image of 5kuj
HUMAN MITOCHONDRIAL CALCIUM UNIPORTER (RESIDUES 72-189) CRYSTAL STRUCTURE WITH MAGNESIUM.
Descriptor:Calcium uniporter protein, mitochondrial, MAGNESIUM ION
Authors:Mok, M.C.Y., Lee, S.K., Junop, M.S., Stathopulos, P.B.
Deposit date:2016-07-13
Release date:2016-09-07
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations.
Cell Chem Biol, 23, 2016
3U7K
  • Download 3u7k
  • View 3u7k
Molmil generated image of 3u7k
CRYSTAL STRUCTURES OF THE STAPHYLOCOCCUS AUREUS PEPTIDE DEFORMYLASE IN COMPLEX WITH TWO CLASSES OF NEW INHIBITORS
Descriptor:Peptide deformylase, (S)-N-(cyclopentylmethyl)-N-(2-(hydroxyamino)-2-oxoethyl)-2-(3-(2-methoxyphenyl)ureido)-3,3-dimethylbutanamide, ZINC ION
Authors:Lee, S.J., Lee, S.-J., Lee, S.K., Yoon, H.-J., Lee, H.H., Kim, K.K., Lee, B.J., Suh, S.W.
Deposit date:2011-10-14
Release date:2012-06-27
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Acta Crystallogr.,Sect.D, 68, 2012
3U7L
  • Download 3u7l
  • View 3u7l
Molmil generated image of 3u7l
CRYSTAL STRUCTURES OF THE STAPHYLOCOCCUS AUREUS PEPTIDE DEFORMYLASE IN COMPLEX WITH TWO CLASSES OF NEW INHIBITORS
Descriptor:Peptide deformylase, ZINC ION, (S)-N-(cyclopentylmethyl)-2-(3-(3,5-difluorophenyl)ureido)-N-(2-(hydroxyamino)-2-oxoethyl)-3,3-dimethylbutanamide
Authors:Lee, S.J., Lee, S.-J., Lee, S.K., Yoon, H.-J., Lee, H.H., Kim, K.K., Lee, B.J., Suh, S.W.
Deposit date:2011-10-14
Release date:2012-06-27
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Acta Crystallogr.,Sect.D, 68, 2012
3U7M
  • Download 3u7m
  • View 3u7m
Molmil generated image of 3u7m
CRYSTAL STRUCTURES OF THE STAPHYLOCOCCUS AUREUS PEPTIDE DEFORMYLASE IN COMPLEX WITH TWO CLASSES OF NEW INHIBITORS
Descriptor:Peptide deformylase, ZINC ION, N-((2R,4S)-2-butyl-4-(3-(2-fluorophenyl)ureido)-5-methyl-3-oxohexyl)-N-hydroxyformamide
Authors:Lee, S.J., Lee, S.-J., Lee, S.K., Yoon, H.-J., Lee, H.H., Kim, K.K., Lee, B.J., Suh, S.W.
Deposit date:2011-10-14
Release date:2012-06-27
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Acta Crystallogr.,Sect.D, 68, 2012
3U7N
  • Download 3u7n
  • View 3u7n
Molmil generated image of 3u7n
CRYSTAL STRUCTURES OF THE STAPHYLOCOCCUS AUREUS PEPTIDE DEFORMYLASE IN COMPLEX WITH TWO CLASSES OF NEW INHIBITORS
Descriptor:Peptide deformylase, ZINC ION, N-((2R,4S)-2-butyl-5-methyl-4-(3-(5-methylpyridin-2-yl)ureido)-3-oxohexyl)-N-hydroxyformamide
Authors:Lee, S.J., Lee, S.-J., Lee, S.K., Yoon, H.-J., Lee, H.H., Kim, K.K., Lee, B.J., Suh, S.W.
Deposit date:2011-10-14
Release date:2012-06-27
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Acta Crystallogr.,Sect.D, 68, 2012
1Q1Y
  • Download 1q1y
  • View 1q1y
Molmil generated image of 1q1y
CRYSTAL STRUCTURES OF PEPTIDE DEFORMYLASE FROM STAPHYLOCOCCUS AUREUS COMPLEXED WITH ACTINONIN
Descriptor:Peptide deformylase, ZINC ION, ACTINONIN
Authors:Yoon, H.J., Lee, S.K., Kim, H.L., Kim, H.W., Kim, H.W., Lee, J.Y., Mikami, B., Suh, S.W.
Deposit date:2003-07-23
Release date:2004-07-23
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of peptide deformylase from Staphylococcus aureus in complex with actinonin, a naturally occurring antibacterial agent
Proteins, 57, 2004
2JRV
  • Download 2jrv
  • View 2jrv
Molmil generated image of 2jrv
THE THIRD DIMENSIONAL STRUCTURE OF MAB198-BOUND PEP.1 FOR AUTOIMMUNE MYASTHENIA GRAVIS
Descriptor:PEPTIDE PEP.1
Authors:Jung, H.H., Yi, H.J., Lee, S.K., Lee, J.Y., Jung, H.J., Yang, S.T., Eu, Y.-J., Im, S.-H., Kim, J.I.
Deposit date:2007-06-29
Release date:2008-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural analysis of immunotherapeutic peptides for autoimmune Myasthenia gravis
Biochemistry, 46, 2007
2JRW
  • Download 2jrw
  • View 2jrw
Molmil generated image of 2jrw
SOLUTION STRUCTURE OF CYCLIC EXTENDED PEP1(CYC.EXT.PEP.1) FOR AUTOIMMUNE MYASTHENIA GRAVIS
Descriptor:Cyclic extended Pep.1
Authors:Jung, H.H., Yi, H.J., Lee, S.K., Lee, J.Y., Jung, H.J., Yang, S.T., Eu, Y.-J., Im, S.-H., Kim, J.I.
Deposit date:2007-06-29
Release date:2008-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural analysis of immunotherapeutic peptides for autoimmune Myasthenia gravis
Biochemistry, 46, 2007
2WH9
  • Download 2wh9
  • View 2wh9
Molmil generated image of 2wh9
SOLUTION STRUCTURE OF GXTX-1E
Descriptor:GUANGXITOXIN-1EGXTX-1E
Authors:Lee, S.K., Jung, H.H., Lee, J.Y., Lee, C.W., Kim, J.I.
Deposit date:2009-05-02
Release date:2010-05-26
Last modified:2017-04-19
Method:SOLUTION NMR
Cite:Solution Structure of Gxtx-1E, a High Affinity Tarantula Toxin Interacting with Voltage Sensors in Kv2.1 Potassium Channels.
Biochemistry, 49, 2010
5Y3N
  • Download 5y3n
  • View 5y3n
Molmil generated image of 5y3n
STRUCTURE OF TRAP1 COMPLEXED WITH DN401
Descriptor:Heat shock protein 75 kDa, mitochondrial, 1-[(6-bromanyl-1,3-benzodioxol-5-yl)methyl]-4-chloranyl-pyrazolo[3,4-d]pyrimidin-6-amine
Authors:Jeong, H., Park, H.K., Kang, S., Kang, B.H., Lee, C.
Deposit date:2017-07-29
Release date:2017-08-30
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors.
J. Med. Chem., 60, 2017
5Y3O
  • Download 5y3o
  • View 5y3o
Molmil generated image of 5y3o
STRUCTURE OF TRAP1 COMPLEXED WITH DN320
Descriptor:Heat shock protein 75 kDa, mitochondrial, 4-chloranyl-1-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methyl]pyrazolo[3,4-d]pyrimidin-6-amine
Authors:Jeong, H., Park, H.K., Kang, S., Kang, B.H., Lee, C.
Deposit date:2017-07-29
Release date:2017-08-30
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors.
J. Med. Chem., 60, 2017
1IX1
  • Download 1ix1
  • View 1ix1
Molmil generated image of 1ix1
CRYSTAL STRUCTURE OF P.AERUGINOSA PEPTIDE DEFORMYLASE COMPLEXED WITH ANTIBIOTIC ACTINONIN
Descriptor:peptide deformylase, ZINC ION, ACTINONIN, ...
Authors:Kim, H.-W., Yoon, H.-J., Lee, J.Y., Han, B.W., Yang, J.K., Lee, B.I., Ahn, H.J., Lee, H.H., Suh, S.W.
Deposit date:2002-06-07
Release date:2003-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of peptide deformylase from Staphylococcus aureus in complex with actinonin, a naturally occurring antibacterial agent
Proteins, 57, 2004
3F3M
  • Download 3f3m
  • View 3f3m
Molmil generated image of 3f3m
SIX CRYSTAL STRUCTURES OF TWO PHOSPHOPANTETHEINE ADENYLYLTRANSFERASES REVEAL AN ALTERNATIVE LIGAND BINDING MODE AND AN ASSOCIATED STRUCTURAL CHANGE
Descriptor:Phosphopantetheine adenylyltransferase, 3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE SULFATE
Authors:Lee, H.H., Yoon, H.J., Suh, S.W.
Deposit date:2008-10-31
Release date:2009-10-20
Last modified:2012-04-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of Staphylococcus aureus phosphopantetheine adenylyltransferase in complex with 3'-phosphoadenosine 5'-phosphosulfate reveals a new ligand-binding mode
Acta Crystallogr.,Sect.F, 65, 2009
2GJL
  • Download 2gjl
  • View 2gjl
Molmil generated image of 2gjl
CRYSTAL STRUCTURE OF 2-NITROPROPANE DIOXYGENASE
Descriptor:hypothetical protein PA1024, FLAVIN MONONUCLEOTIDE
Authors:Suh, S.W.
Deposit date:2006-03-31
Release date:2006-05-16
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of 2-Nitropropane Dioxygenase Complexed with FMN and Substrate: identification of the catalytic base
J.Biol.Chem., 281, 2006
2GJN
  • Download 2gjn
  • View 2gjn
Molmil generated image of 2gjn
CRYSTAL STRUCTURE OF 2-NITROPROPANE DIOXYGENASE COMPLEXED WITH FMN AND SUBSTRATE
Descriptor:hypothetical protein PA1024, FLAVIN MONONUCLEOTIDE, 2-NITROPROPANE
Authors:Suh, S.W.
Deposit date:2006-03-31
Release date:2006-05-16
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of 2-Nitropropane Dioxygenase Complexed with FMN and Substrate: identification of the catalytic base
J.Biol.Chem., 281, 2006
4N44
  • Download 4n44
  • View 4n44
Molmil generated image of 4n44
CRYSTAL STRUCTURE OF OXIDIZED FORM OF THIOLASE FROM CLOSTRIDIUM ACETOBUTYLICUM
Descriptor:Acetyl-CoA acetyltransferase, ACETATE ION, GLYCEROL
Authors:Kim, S., Ha, S.C., Ahn, J.W., Kim, E.J., Lim, J.H., Kim, K.J.
Deposit date:2013-10-08
Release date:2014-10-08
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural insight into redox-switch regulatory mechanism of thiolase from the n-butanol synthesizing bacterium, Clostridium acetobutylicum
to be published
4N45
  • Download 4n45
  • View 4n45
Molmil generated image of 4n45
CRYSTAL STRUCTURE OF REDUCED FORM OF THIOLASE FROM CLOSTRIDIUM ACETOBUTYLICUM
Descriptor:Acetyl-CoA acetyltransferase
Authors:Kim, S., Ha, S.C., Ahn, J.W., Kim, E.J., Lim, J.H., Kim, K.J.
Deposit date:2013-10-08
Release date:2014-10-08
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insight into redox-switch regulatory mechanism of thiolase from the n-butanol synthesizing bacterium, Clostridium acetobutylicum
to be published
5WAS
  • Download 5was
  • View 5was
Molmil generated image of 5was
CORYNEBACTERIUM GLUTAMICUM HYDROLYZED HOMOSERINE KINASE
Descriptor:Homoserine kinase, PHOSPHATE ION
Authors:Petit, C., Ronning, D.R.
Deposit date:2017-06-27
Release date:2018-02-07
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Reduction of Feedback Inhibition in Homoserine Kinase (ThrB) ofCorynebacterium glutamicumEnhances l-Threonine Biosynthesis.
ACS Omega, 3, 2018
5WAT
  • Download 5wat
  • View 5wat
Molmil generated image of 5wat
CORYNEBACTERIUM GLUTAMICUM FULL LENGTH HOMOSERINE KINASE
Descriptor:Homoserine kinase, PHOSPHATE ION, HEXAETHYLENE GLYCOL, ...
Authors:Petit, C., Ronning, D.R.
Deposit date:2017-06-27
Release date:2018-02-07
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (2.141 Å)
Cite:Reduction of Feedback Inhibition in Homoserine Kinase (ThrB) ofCorynebacterium glutamicumEnhances l-Threonine Biosynthesis.
ACS Omega, 3, 2018