3U7M

Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors

Summary for 3U7M

Related3U7K 3U7L 3U7N
DescriptorPeptide deformylase, ZINC ION, N-((2R,4S)-2-butyl-4-(3-(2-fluorophenyl)ureido)-5-methyl-3-oxohexyl)-N-hydroxyformamide, ... (4 entities in total)
Functional Keywordspdf-inhibitor, pdf, peptide deformylase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceStaphylococcus aureus
Total number of polymer chains1
Total molecular weight22139.56
Authors
Lee, S.J.,Lee, S.-J.,Lee, S.K.,Yoon, H.-J.,Lee, H.H.,Kim, K.K.,Lee, B.J.,Suh, S.W. (deposition date: 2011-10-14, release date: 2012-06-27, Last modification date: 2017-03-01)
Primary citation
Lee, S.J.,Lee, S.-J.,Lee, S.K.,Yoon, H.-J.,Lee, H.H.,Kim, K.K.,Lee, B.J.,Lee, B.I.,Suh, S.W.
Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Acta Crystallogr.,Sect.D, 68:784-793, 2012
PubMed: 22751663 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444912011912
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.15 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.229500.6%8.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
167327
PDB entries from 2020-08-05