3U7M

Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006412	biological_process	translation
A	0016787	molecular_function	hydrolase activity
A	0042586	molecular_function	peptide deformylase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 350

Chain	Residue
A	GLN65
A	CSD111
A	HIS154
A	HIS158
A	FHF192

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site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE FHF A 192

Chain	Residue
A	GLY60
A	GLN65
A	GLY110
A	CSD111
A	LEU112
A	TYR147
A	HIS154
A	GLU155
A	HIS158
A	GLU185
A	ZN350
A	ARG56
A	SER57
A	GLY58
A	VAL59

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00163

Chain	Residue	Details
A	GLU155

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00163

Chain	Residue	Details
A	CSD111
A	HIS154
A	HIS158

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