3U7M

Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Peptide deformylase	polymer	191	21692.7	1	UniProt (Q5HGZ3) Pfam (PF01327) In PDB	Staphylococcus aureus	PDF, Polypeptide deformylase
2	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	A	N-((2R,4S)-2-butyl-4-(3-(2-fluorophenyl)ureido)-5-methyl-3-oxohexyl)-N-hydroxyformamide	non-polymer		381.4	1	Chemie (FHF)
4		water	water		18.0	113	Chemie (HOH)

Sequence modifications

A: 1 - 183 (UniProt: Q5HGZ3)

PDB	External Database	Details
Leu 184	-	expression tag
Glu 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	21692.7
Non-Polymers*	Number of molecules	2
	Total formula weight	446.9
All*	Total formula weight	22139.6

*Water molecules are not included.