5KUE

Human SeMet incorporated I141M/L146M mitochondrial calcium uniporter (residues 72-189) crystal structure with magnesium

Summary for 5KUE

Entry DOI	10.2210/pdb5kue/pdb
Related	5KUG 5KUI 5KUJ
Descriptor	Calcium uniporter protein, mitochondrial, MAGNESIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
Functional Keywords	beta-grasp fold i141m/l146m se-met double mutant n-terminal domain residues 72-189 mitochondrial calcium uniporter, transport protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	14305.49
Authors	Mok, C.Y.M.,Lee, S.K.,Junop, M.S.,Stathopulos, P.B. (deposition date: 2016-07-13, release date: 2016-09-07, Last modification date: 2020-01-08)
Primary citation	Lee, S.K.,Shanmughapriya, S.,Mok, M.C.,Dong, Z.,Tomar, D.,Carvalho, E.,Rajan, S.,Junop, M.S.,Madesh, M.,Stathopulos, P.B. Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations. Cell Chem Biol, 23:1157-1169, 2016 Cited by PubMed: 27569754 DOI: 10.1016/j.chembiol.2016.07.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation