5KUE
Human SeMet incorporated I141M/L146M mitochondrial calcium uniporter (residues 72-189) crystal structure with magnesium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calcium uniporter protein, mitochondrial | polymer | 124 | 14010.6 | 1 | UniProt (Q8NE86) Pfam (PF04678) | Homo sapiens (Human) | Coiled-coil domain-containing protein 109A |
| 2 | B, C (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 4 | E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | G (A) | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
A: 72 - 189 (UniProt: Q8NE86)
| PDB | External Database | Details |
|---|---|---|
| Gly 66 | - | expression tag |
| Ser 67 | - | expression tag |
| His 68 | - | expression tag |
| Met 69 | - | expression tag |
| Ala 70 | - | expression tag |
| Ser 71 | - | expression tag |
| Mse 141 | Ile 141 | engineered mutation |
| Mse 146 | Leu 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14010.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 294.9 | |
| All* | Total formula weight | 14305.5 |
