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1UDT
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CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 5 COMPLEXED WITH SILDENAFIL(VIAGRA)
Descriptor:cGMP-specific 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION, ...
Authors:Sung, B.-J., Lee, J.I., Heo, Y.-S., Kim, J.H., Moon, J., Yoon, J.M., Hyun, Y.-L., Kim, E., Eum, S.J., Lee, T.G., Cho, J.M., Park, S.-Y., Lee, J.-O., Jeon, Y.H., Hwang, K.Y., Ro, S.
Deposit date:2003-05-06
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules
Nature, 425, 2003
1UDU
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CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 5 COMPLEXED WITH TADALAFIL(CIALIS)
Descriptor:cGMP-specific 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION, ...
Authors:Sung, B.-J., Lee, J.I., Heo, Y.-S., Kim, J.H., Moon, J., Yoon, J.M., Hyun, Y.-L., Kim, E., Eum, S.J., Lee, T.G., Cho, J.M., Park, S.-Y., Lee, J.-O., Jeon, Y.H., Hwang, K.Y., Ro, S.
Deposit date:2003-05-06
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules
Nature, 425, 2003
1UHO
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CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 5 COMPLEXED WITH VARDENAFIL(LEVITRA)
Descriptor:cGMP-specific 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION, ...
Authors:Sung, B.-J., Lee, J.I., Heo, Y.-S., Kim, J.H., Moon, J., Yoon, J.M., Hyun, Y.-L., Kim, E., Eum, S.J., Lee, T.G., Cho, J.M., Park, S.-Y., Lee, J.-O., Jeon, Y.H., Hwang, K.Y., Ro, S.
Deposit date:2003-07-09
Release date:2004-07-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules
Nature, 425, 2003
1UKH
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STRUCTURAL BASIS FOR THE SELECTIVE INHIBITION OF JNK1 BY THE SCAFFOLDING PROTEIN JIP1 AND SP600125
Descriptor:Mitogen-activated protein kinase 8 isoform 4, 11-mer peptide from C-jun-amino-terminal kinase interacting protein 1
Authors:Heo, Y.-S., Kim, Y.K., Sung, B.-J., Lee, H.S., Lee, J.I., Seo, C.I., Park, S.-Y., Kim, J.H., Hyun, Y.-L., Jeon, Y.H., Ro, S., Lee, T.G., Cho, J.M., Hwang, K.Y., Yang, C.-H.
Deposit date:2003-08-23
Release date:2004-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125
Embo J., 23, 2004
1UKI
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STRUCTURAL BASIS FOR THE SELECTIVE INHIBITION OF JNK1 BY THE SCAFFOLDING PROTEIN JIP1 AND SP600125
Descriptor:mitogen-activated protein kinase 8 isoform 4, 11-mer peptide from C-jun-amino-terminal kinase interacting protein 1, 2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE
Authors:Heo, Y.-S., Kim, Y.K., Sung, B.-J., Lee, H.S., Lee, J.I., Seo, C.I., Park, S.-Y., Kim, J.H., Hyun, Y.-L., Jeon, Y.H., Ro, S., Lee, T.G., Cho, J.M., Hwang, K.Y., Yang, C.-H.
Deposit date:2003-08-23
Release date:2004-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125
Embo J., 23, 2004
2HJW
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CRYSTAL STRUCTURE OF THE BC DOMAIN OF ACC2
Descriptor:Acetyl-CoA carboxylase 2
Authors:Cho, Y.S., Lee, J.I., Shin, D., Kim, H.T., Lee, T.G., Heo, Y.S.
Deposit date:2006-07-02
Release date:2007-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2.
Proteins, 70, 2008
3JRW
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PHOSPHORYLATED BC DOMAIN OF ACC2
Descriptor:Acetyl-CoA carboxylase 2
Authors:Cho, Y.S., Lee, J.I., Shin, D., Kim, H.T., Lee, T.G., Heo, Y.S.
Deposit date:2009-09-09
Release date:2010-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK
Biochem.Biophys.Res.Commun., 391, 2010
3JRX
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CRYSTAL STRUCTURE OF THE BC DOMAIN OF ACC2 IN COMPLEX WITH SORAPHEN A
Descriptor:Acetyl-CoA carboxylase 2, SORAPHEN A
Authors:Cho, Y.S., Lee, J.I., Shin, D., Kim, H.T., Lee, T.G., Heo, Y.S.
Deposit date:2009-09-09
Release date:2010-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK.
Biochem.Biophys.Res.Commun., 391, 2010
2KCC
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SOLUTION STRUCTURE OF BIOTINOYL DOMAIN FROM HUMAN ACETYL-COA CARBOXYLASE 2
Descriptor:Acetyl-CoA carboxylase 2
Authors:Lee, C., Cheong, H., Ryu, K., Lee, J., Lee, W., Jeon, Y., Cheong, C.
Deposit date:2008-12-19
Release date:2009-02-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Biotinoyl domain of human acetyl-CoA carboxylase: Structural insights into the carboxyl transfer mechanism.
Proteins, 72, 2008
4OWI
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PEPTIDE STRUCTURE
Descriptor:p53LZ2
Authors:Lee, J.-H.
Deposit date:2014-02-02
Release date:2014-05-21
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (1.202 Å)
Cite:Protein grafting of p53TAD onto a leucine zipper scaffold generates a potent HDM dual inhibitor.
Nat Commun, 5, 2014