Author results

1IZ3
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DIMERIC STRUCTURE OF FIH (FACTOR INHIBITING HIF)
Descriptor:FIH, SULFATE ION
Authors:Lee, C., Kim, S.-J., Jeong, D.-G., Lee, S.M., Ryu, S.-E.
Deposit date:2002-09-19
Release date:2003-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau.
J.Biol.Chem., 278, 2003
1N4M
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STRUCTURE OF RB TUMOR SUPPRESSOR BOUND TO THE TRANSACTIVATION DOMAIN OF E2F-2
Descriptor:Retinoblastoma Pocket, Transcription factor E2F2
Authors:Lee, C., Chang, J.H., Lee, H.S., Cho, Y.
Deposit date:2002-10-31
Release date:2003-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor
GENES DEV., 16, 2002
4Z1F
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CRYSTAL STRUCTURE OF HUMAN TRAP1 WITH PU-H71
Descriptor:Heat shock protein 75 kDa, mitochondrial, 8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE
Authors:Lee, C., Park, H.K., Ryu, J.H., Kang, B.H.
Deposit date:2015-03-27
Release date:2015-04-22
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
4Z1G
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CRYSTAL STRUCTURE OF HUMAN TRAP1 WITH BIIB-021
Descriptor:Heat shock protein 75 kDa, mitochondrial, 6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine
Authors:Lee, C., Park, H.K., Ryu, J.H., Kang, B.H.
Deposit date:2015-03-27
Release date:2015-04-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
4Z1H
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CRYSTAL STRUCTURE OF HUMAN TRAP1 WITH SMTIN-P01
Descriptor:Heat shock protein 75 kDa, mitochondrial, 8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[6-(triphenyl-lambda~5~-phosphanyl)hexyl]-9H-purin-6-amine
Authors:Lee, C., Park, H.K., Ryu, J.H., Kang, B.H.
Deposit date:2015-03-27
Release date:2015-04-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
4Z1I
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CRYSTAL STRUCTURE OF HUMAN TRAP1 WITH AMPPNP
Descriptor:Heat shock protein 75 kDa, mitochondrial, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Lee, C., Park, H.K., Ryu, J.H., Kang, B.H.
Deposit date:2015-03-27
Release date:2015-04-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
4BWZ
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CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER, NAPA
Descriptor:NA(+)/H(+) ANTIPORTER, ZINC ION
Authors:Lee, C., Drew, D., Cameron, A.D.
Deposit date:2013-07-05
Release date:2013-08-28
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.984 Å)
Cite:A two-domain elevator mechanism for sodium/proton antiport.
Nature, 501, 2013
5VRE
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CRYSTAL STRUCTURE OF A LYSOSOMAL POTASSIUM-SELECTIVE CHANNEL TMEM175 HOMOLOG FROM CHAMAESIPHON MINUTUS
Descriptor:Putative integral membrane protein
Authors:Lee, C., Guo, J., Jiang, Y.
Deposit date:2017-05-10
Release date:2017-07-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.299 Å)
Cite:The lysosomal potassium channel TMEM175 adopts a novel tetrameric architecture.
Nature, 547, 2017
2JRL
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SOLUTION STRUCTURE OF THE BERYLLOFLUORIDE-ACTIVATED NTRC4 RECEIVER DOMAIN DIMER
Descriptor:Transcriptional regulator (NtrC family)
Authors:Lee, C., Hong, E., Doucleff, M., Pelton, J.G., Wemmer, D.E., Berkeley Structural Genomics Center (BSGC)
Deposit date:2007-06-27
Release date:2008-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the Beryllofluoride-Activated NtrC4 Receiver Domain Dimer.
To be Published
3MKQ
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CRYSTAL STRUCTURE OF YEAST ALPHA/BETAPRIME-COP SUBCOMPLEX OF THE COPI VESICULAR COAT
Descriptor:Coatomer beta'-subunit, Coatomer subunit alpha
Authors:Lee, C., Goldberg, J.
Deposit date:2010-04-15
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats.
Cell(Cambridge,Mass.), 142, 2010
3MKR
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CRYSTAL STRUCTURE OF YEAST ALPHA/EPSILON-COP SUBCOMPLEX OF THE COPI VESICULAR COAT
Descriptor:Coatomer subunit epsilon, Coatomer subunit alpha
Authors:Lee, C., Goldberg, J.
Deposit date:2010-04-15
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats.
Cell(Cambridge,Mass.), 142, 2010
5H20
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X-RAY STRUCTURE OF PADR-LIKE TRANSCRIPTION FACTOR FROM BACTEROID FRAGILIS
Descriptor:Putative PadR-family transcriptional regulatory protein, PHOSPHATE ION, ALPHA-D-GLUCOSE, ...
Authors:Lee, C., Hong, M.
Deposit date:2016-10-13
Release date:2017-03-08
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional analysis of BF2549, a PadR-like transcription factor from Bacteroides fragilis.
Biochem. Biophys. Res. Commun., 483, 2017
5XEF
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CRYSTAL STRUCTURE OF FLAGELLAR CHAPERONE FROM BACTERIA
Descriptor:Flagellar protein fliS
Authors:Lee, C., Hong, M.
Deposit date:2017-04-05
Release date:2018-06-27
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the flagellar chaperone FliS from Bacillus cereus and an invariant proline critical for FliS dimerization and flagellin recognition
Biochem. Biophys. Res. Commun., 487, 2017
6ABQ
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CRYSTAL STRUCTURE OF TRANSCRIPTION FACTOR FROM LISTERIA MONOCYTOGENES
Descriptor:PadR family transcriptional regulator, CHLORIDE ION
Authors:Lee, C., Hong, M.
Deposit date:2018-07-23
Release date:2019-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based molecular characterization and regulatory mechanism of the LftR transcription factor from Listeria monocytogenes: Conformational flexibilities and a ligand-induced regulatory mechanism.
Plos One, 14, 2019
6ABT
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CRYSTAL STRUCTURE OF TRANSCRIPTION FACTOR FROM LISTERIA MONOCYTOGENES
Descriptor:PadR family transcriptional regulator
Authors:Lee, C., Hong, M.
Deposit date:2018-07-23
Release date:2019-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-based molecular characterization and regulatory mechanism of the LftR transcription factor from Listeria monocytogenes: Conformational flexibilities and a ligand-induced regulatory mechanism.
Plos One, 14, 2019
2JTN
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NMR SOLUTION STRUCTURE OF A LDB1-LID:LHX3-LIM COMPLEX
Descriptor:LIM domain-binding protein 1, LIM/homeobox protein Lhx3, ZINC ION
Authors:Lee, C., Nancarrow, A.L., Mackay, J.P., Matthews, J.M.
Deposit date:2007-08-03
Release date:2008-06-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes
Embo J., 27, 2008
4ATV
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STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH
Descriptor:NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION, DODECYL-ALPHA-D-MALTOSIDE
Authors:Drew, D., Lee, C., Iwata, S., Cameron, A.D.
Deposit date:2012-05-10
Release date:2013-07-10
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
4AU5
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STRUCTURE OF THE NHAA DIMER, CRYSTALLISED AT LOW PH
Descriptor:NA(+)/H(+) ANTIPORTER NHAA, DODECYL-ALPHA-D-MALTOSIDE, SULFATE ION
Authors:Drew, D., Lee, C., Iwata, S., Cameron, A.D.
Deposit date:2012-05-14
Release date:2013-07-10
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.696 Å)
Cite:Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
2HIW
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CRYSTAL STRUCTURE OF INACTIVE CONFORMATION ABL KINASE CATALYTIC DOMAIN COMPLEXED WITH TYPE II INHIBITOR
Descriptor:Proto-oncogene tyrosine-protein kinase ABL1, 7-AMINO-1-METHYL-3-(2-METHYL-5-{[3-(TRIFLUOROMETHYL)BENZOYL]AMINO}PHENYL)-2-OXO-2,3-DIHYDROPYRIMIDO[4,5-D]PYRIMIDIN-1-IUM
Authors:Lee, C.
Deposit date:2006-06-29
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A general strategy for creating
Chem.Biol., 13, 2006
2ZXX
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CRYSTAL STRUCTURE OF CDT1/GEMININ COMPLEX
Descriptor:Geminin, DNA replication factor Cdt1
Authors:Cho, Y., Lee, C., Hong, B.S., Choi, J.M.
Deposit date:2009-01-08
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for inhibition of the replication licensing factor Cdt1 by geminin
Nature, 430, 2004
5Y3N
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STRUCTURE OF TRAP1 COMPLEXED WITH DN401
Descriptor:Heat shock protein 75 kDa, mitochondrial, 1-[(6-bromanyl-1,3-benzodioxol-5-yl)methyl]-4-chloranyl-pyrazolo[3,4-d]pyrimidin-6-amine
Authors:Jeong, H., Park, H.K., Kang, S., Kang, B.H., Lee, C.
Deposit date:2017-07-29
Release date:2017-08-30
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors.
J. Med. Chem., 60, 2017
5Y3O
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STRUCTURE OF TRAP1 COMPLEXED WITH DN320
Descriptor:Heat shock protein 75 kDa, mitochondrial, 4-chloranyl-1-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methyl]pyrazolo[3,4-d]pyrimidin-6-amine
Authors:Jeong, H., Park, H.K., Kang, S., Kang, B.H., Lee, C.
Deposit date:2017-07-29
Release date:2017-08-30
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors.
J. Med. Chem., 60, 2017
6II0
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CRYSTAL STRUCTURE OF THE MAKES CATERPILLARS FLOPPY (MCF)-LIKE EFFECTOR OF VIBRIO VULNIFICUS MO6-24/O
Descriptor:Putative RTX-toxin, GLYCEROL
Authors:Lee, Y., Kim, B.S., Choi, S., Lee, E.Y., Park, S., Hwang, J., Kwon, Y., Hyun, J., Lee, C., Eom, S.H., Kim, M.H.
Deposit date:2018-10-03
Release date:2019-08-07
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Crystal Structure of Pathogenic Bacterial Toxin A
To Be Published
6II2
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CRYSTAL STRUCTURE OF ALPHA-BETA HYDROLASE (ABH) AND MAKES CATERPILLARS FLOPPY (MCF)-LIKE EFFECTORS OF VIBRIO VULNIFICUS MO6-24/O
Descriptor:Putative RTX-toxin
Authors:Lee, Y., Kim, B.S., Choi, S., Lee, E.Y., Park, S., Hwang, J., Kwon, Y., Hyung, J., Lee, C., Eom, S.H., Kim, M.H.
Deposit date:2018-10-03
Release date:2019-08-07
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal Structure of Pathogenic Bacterial Toxin AB
To Be Published
6II6
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CRYSTAL STRUCTURE OF THE MAKES CATERPILLARS FLOPPY (MCF)-LIKE EFFECTOR OF VIBRIO VULNIFICUS MO6-24/O IN COMPLEX WITH A HUMAN ADP-RIBOSYLATION FACTOR 3 (ARF3)
Descriptor:Putative RTX-toxin, ADP-ribosylation factor 3, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Lee, Y., Kim, B.S., Choi, S., Lee, E.Y., Park, S., Hwang, J., Kwon, Y., Hyun, J., Lee, C., Eom, S.H., Kim, M.H.
Deposit date:2018-10-03
Release date:2019-08-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Pathogenic Bacterial Toxin A with a Host Protein
To Be Published