Author results

6MS1
  • Download 6ms1
  • View 6ms1
Molmil generated image of 6ms1
CRYSTAL STRUCTURE OF THE HUMAN SCRIBBLE PDZ1 DOMAIN BOUND TO THE PDZ-BINDING MOTIF OF APC
Descriptor:Protein scribble homolog, APC C-terminus peptide, 1,2-ETHANEDIOL
Authors:How, J.Y., Kvansakul, M., Caria, S., Humbert, P.O.
Deposit date:2018-10-16
Release date:2019-02-06
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC.
FEBS Lett., 2019
6H1N
  • Download 6h1n
  • View 6h1n
Molmil generated image of 6h1n
CRYSTAL STRUCTURE OF A ZEBRA-FISH PRO-SURVIVAL PROTEIN NRZ-APO
Descriptor:BCL2-like 10 (Apoptosis facilitator), SULFATE ION, ACETATE ION
Authors:Suraweera, C.D., Hinds, M.G., Kvansakul, M.
Deposit date:2018-07-12
Release date:2018-10-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:A structural investigation of NRZ mediated apoptosis regulation in zebrafish.
Cell Death Dis, 9, 2018
6CS9
  • Download 6cs9
  • View 6cs9
Molmil generated image of 6cs9
CRYSTAL STRUCTURE OF HUMAN BETA-DEFENSIN 2 IN COMPLEX WITH PIP2
Descriptor:Beta-defensin 4A, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Jarva, M., Phan, K., Lay, F.T., Humble, C., Hulett, M., Kvansakul, M.
Deposit date:2018-03-20
Release date:2018-07-25
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Human beta-defensin 2 killsCandida albicansthrough phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization.
Sci Adv, 4, 2018
6B55
  • Download 6b55
  • View 6b55
Molmil generated image of 6b55
CRYSTAL STRUCTURE OF THE PLANT DEFENSIN NAD1 COMPLEXED WITH PHOSPHATIDIC ACID
Descriptor:Flower-specific defensin, 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, PHOSPHATE ION, ...
Authors:Jarva, M., Phan, K., Humble, C., Lay, F.T., Hulett, M., Kvansakul, M.
Deposit date:2017-09-28
Release date:2018-05-23
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex.
Nat Commun, 9, 2018
5WOU
  • Download 5wou
  • View 5wou
Molmil generated image of 5wou
CRYSTAL STRUCTURE OF DROSOPHILA MELANOGASTER SCRIBBLE PDZ1 DOMAIN IN COMPLEX WITH GUK-HOLDER
Descriptor:Protein lap4, GUK-holder, isoform A, ...
Authors:Caria, S., Kvansakul, M.
Deposit date:2017-08-03
Release date:2018-02-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Drosophila melanogasterGuk-holder interacts with the Scribbled PDZ1 domain and regulates epithelial development with Scribbled and Discs Large.
J. Biol. Chem., 293, 2018
5WOS
  • Download 5wos
  • View 5wos
Molmil generated image of 5wos
STRUCTURAL AND FUNCTIONAL INSIGHTS INTO CANARYPOX VIRUS CNP058 REGULATION OF APOPTOSIS
Descriptor:CNPV058 bcl-2 like protein, Bcl-2-like protein 11
Authors:Anasir, M.I., Kvansakul, M.
Deposit date:2017-08-02
Release date:2017-11-01
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural and Functional Insight into Canarypox Virus CNP058 Mediated Regulation of Apoptosis.
Viruses, 9, 2017
5VYP
  • Download 5vyp
  • View 5vyp
Molmil generated image of 5vyp
CRYSTAL STRUCTURE OF THE PLANT DEFENSIN NSD7 BOUND TO PIP2
Descriptor:Defensin NsD7, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, SULFATE ION, ...
Authors:Jarva, M., Lay, F.T., Hulett, M., Kvansakul, M.
Deposit date:2017-05-25
Release date:2017-08-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the defensin NsD7 in complex with PIP2 reveals that defensin : lipid oligomer topologies are dependent on lipid type.
FEBS Lett., 591, 2017
5VWI
  • Download 5vwi
  • View 5vwi
Molmil generated image of 5vwi
CRYSTAL STRUCTURE OF HUMAN SCRIBBLE PDZ1:BETA-PIX COMPLEX
Descriptor:Protein scribble homolog, beta-PIX
Authors:Lim, K.Y.B., Kvansakul, M.
Deposit date:2017-05-22
Release date:2017-11-08
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX.
J. Biol. Chem., 292, 2017
5VWK
  • Download 5vwk
  • View 5vwk
Molmil generated image of 5vwk
CRYSTAL STRUCTURE OF HUMAN SCRIBBLE PDZ1:BETA-PIX COMPLEX
Descriptor:Protein scribble homolog, Beta-PIX, SULFATE ION
Authors:Lim, K.Y.B., Kvansakul, M.
Deposit date:2017-05-22
Release date:2017-11-08
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX.
J. Biol. Chem., 292, 2017
5VWC
  • Download 5vwc
  • View 5vwc
Molmil generated image of 5vwc
CRYSTAL STRUCTURE OF HUMAN SCRIBBLE PDZ1 DOMAIN
Descriptor:Protein scribble homolog, 1,2-ETHANEDIOL
Authors:Lim, K.Y.B., Kvansakul, M.
Deposit date:2017-05-21
Release date:2017-11-08
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (1.911 Å)
Cite:Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX.
J. Biol. Chem., 292, 2017
5VMO
  • Download 5vmo
  • View 5vmo
Molmil generated image of 5vmo
CRYSTAL STRUCTURE OF GROUPER IRIDOVIRUS GIV66:BIM COMPLEX
Descriptor:Bak protein, Bcl-2 interacting mediator of cell death, PENTAETHYLENE GLYCOL, ...
Authors:Banjara, S., Kvansakul, M.
Deposit date:2017-04-28
Release date:2018-03-07
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim.
J. Biol. Chem., 293, 2018
5VMN
  • Download 5vmn
  • View 5vmn
Molmil generated image of 5vmn
CRYSTAL STRUCTURE OF GROUPER IRIDOVIRUS GIV66
Descriptor:Bak protein, NITRATE ION, 1,2-ETHANEDIOL
Authors:Banjara, S., Kvansakul, M.
Deposit date:2017-04-27
Release date:2018-03-07
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim.
J. Biol. Chem., 293, 2018
5UA5
  • Download 5ua5
  • View 5ua5
Molmil generated image of 5ua5
CRYSTAL STRUCTURE OF A179L:BID BH3 COMPLEX
Descriptor:5-HL, Uncharacterized protein
Authors:Banjara, S., Caria, S., Kvansakul, M.
Deposit date:2016-12-19
Release date:2017-01-04
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insight into African Swine Fever Virus A179L-Mediated Inhibition of Apoptosis.
J. Virol., 91, 2017
5UA4
  • Download 5ua4
  • View 5ua4
Molmil generated image of 5ua4
CRYSTAL STRUCTURE OF A179L:BID BH3 COMPLEX
Descriptor:5-HL, BH3-interacting domain death agonist
Authors:Banjara, S., Caria, S., Kvansakul, M.
Deposit date:2016-12-18
Release date:2017-01-04
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insight into African Swine Fever Virus A179L-Mediated Inhibition of Apoptosis.
J. Virol., 91, 2017
5TZP
  • Download 5tzp
  • View 5tzp
Molmil generated image of 5tzp
CRYSTAL STRUCTURE OF FPV039:BIK BH3 COMPLEX
Descriptor:Bcl-2-like protein FPV039, Bik, 1,2-ETHANEDIOL, ...
Authors:Anasir, M.I., Kvansakul, M.
Deposit date:2016-11-22
Release date:2017-05-03
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039.
J. Biol. Chem., 292, 2017
5TZQ
  • Download 5tzq
  • View 5tzq
Molmil generated image of 5tzq
CRYSTAL STRUCTURE OF FPV039:BMF BH3 COMPLEX
Descriptor:Bcl-2-like protein FPV039, Bcl-2-modifying factor, 1,2-ETHANEDIOL
Authors:Anasir, M.I., Kvansakul, M.
Deposit date:2016-11-22
Release date:2017-05-03
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039.
J. Biol. Chem., 292, 2017
5TWA
  • Download 5twa
  • View 5twa
Molmil generated image of 5twa
CRYSTAL STRUCTURE OF GEODIA CYDONIUM BHP2 IN COMPLEX WITH LUBOMIRSKIA BAICALENSIS BAK-2
Descriptor:Bcl-x homologous protein, BHP2, BAK-2 protein, ...
Authors:Caria, S., Hinds, M.G., Kvansakul, M.
Deposit date:2016-11-12
Release date:2017-01-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural insight into an evolutionarily ancient programmed cell death regulator - the crystal structure of marine sponge BHP2 bound to LB-Bak-2.
Cell Death Dis, 8, 2017
5KK4
  • Download 5kk4
  • View 5kk4
Molmil generated image of 5kk4
CRYSTAL STRUCTURE OF THE PLANT DEFENSIN NSD7 BOUND TO PHOSPHATIDIC ACID
Descriptor:NsD7, 1,2-ETHANEDIOL, SULFATE ION, ...
Authors:Kvansakul, M., Hulett, M.D., Lay, F.T.
Deposit date:2016-06-21
Release date:2016-10-05
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization.
Proc.Natl.Acad.Sci.USA, 113, 2016
5AEA
  • Download 5aea
  • View 5aea
Molmil generated image of 5aea
CRYSTAL STRUCTURE OF HUMAN NCAM DOMAIN 1
Descriptor:NEURAL CELL ADHESION MOLECULE 1, CITRATE ANION
Authors:Kvansakul, M., Griffiths, K., Foley, M.
Deposit date:2015-08-27
Release date:2016-04-13
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:I-Bodies, Human Single Domain Antibodies that Antagonize Chemokine Receptor Cxcr4.
J.Biol.Chem., 291, 2016
4UJ0
  • Download 4uj0
  • View 4uj0
Molmil generated image of 4uj0
CRYSTAL STRUCTURE OF THE TOMATO DEFENSIN TPP3
Descriptor:FLOWER-SPECIFIC GAMMA-THIONIN-LIKE PROTEIN/ACIDIC PROTEIN, ACETATE ION
Authors:Richter, V., Lay, F.T., Hulett, M.D., Kvansakul, M.
Deposit date:2015-04-07
Release date:2015-04-15
Last modified:2016-04-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Tomato Defensin Tpp3 Binds Phosphatidylinositol (4,5)-Bisphosphate Via a Conserved Dimeric Cationic Grip Conformation to Mediate Cell Lysis.
Mol.Cell.Biol., 35, 2015
5AJJ
  • Download 5ajj
  • View 5ajj
Molmil generated image of 5ajj
CRYSTAL STRUCTURE OF VARIOLA VIRUS VIRULENCE FACTOR F1L IN COMPLEX WITH HUMAN BID BH3 DOMAIN
Descriptor:HOMOLOG OF VACCINIA VIRUS CDS F1L PUTATIVE, BH3-INTERACTING DOMAIN DEATH AGONIST, GLYCEROL, ...
Authors:Kvansakul, M., Colman, P.M.
Deposit date:2015-02-25
Release date:2015-03-25
Last modified:2015-07-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Variola Virus F1L is a Bcl-2-Like Protein that Unlike its Vaccinia Virus Counterpart Inhibits Apoptosis Independent of Bim.
Cell Death Dis., 6, 2015
5AJK
  • Download 5ajk
  • View 5ajk
Molmil generated image of 5ajk
CRYSTAL STRUCTURE OF VARIOLA VIRUS VIRULENCE FACTOR F1L IN COMPLEX WITH HUMAN BAK BH3 DOMAIN
Descriptor:HOMOLOG OF VACCINIA VIRUS CDS F1L, BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, CHLORIDE ION, ...
Authors:Kvansakul, M., Colman, P.M.
Deposit date:2015-02-25
Release date:2015-03-25
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Variola Virus F1L is a Bcl-2-Like Protein that Unlike its Vaccinia Virus Counterpart Inhibits Apoptosis Independent of Bim.
Cell Death Dis., 6, 2015
4UF1
  • Download 4uf1
  • View 4uf1
Molmil generated image of 4uf1
DEERPOX VIRUS DPV022 IN COMPLEX WITH BAK BH3
Descriptor:ANTIAPOPTOTIC MEMBRANE PROTEIN, BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, SULFATE ION
Authors:Burton, D.R., Kvansakul, M.
Deposit date:2014-12-23
Release date:2015-08-05
Last modified:2015-08-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis.
Acta Crystallogr.,Sect.D, 71, 2015
4UF2
  • Download 4uf2
  • View 4uf2
Molmil generated image of 4uf2
DEERPOX VIRUS DPV022 IN COMPLEX WITH BAX BH3
Descriptor:ANTIAPOPTOTIC MEMBRANE PROTEIN, APOPTOSIS REGULATOR BAX
Authors:Burton, D.R., Kvansakul, M.
Deposit date:2014-12-23
Release date:2015-08-05
Last modified:2015-08-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis.
Acta Crystallogr.,Sect.D, 71, 2015
4UF3
  • Download 4uf3
  • View 4uf3
Molmil generated image of 4uf3
DEERPOX VIRUS DPV022 IN COMPLEX WITH BIM BH3
Descriptor:ANTIAPOPTOTIC MEMBRANE PROTEIN, BCL-2-LIKE PROTEIN 11
Authors:Burton, D.R., Kvansakul, M.
Deposit date:2014-12-23
Release date:2015-08-05
Last modified:2015-08-19
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis.
Acta Crystallogr.,Sect.D, 71, 2015
<12>