Author results

5AC9
  • Download 5ac9
  • View 5ac9
Molmil generated image of 5ac9
STRUCTURE-BASED ENERGETICS OF PROTEIN INTERFACES GUIDE FOOT-AND-MOUTH DISEASE VIRUS VACCINE DESIGN
Descriptor:VP1, VP3, VP2, ...
Authors:Kotecha, A., Seago, J., Scott, K., Burman, A., Loureiro, S., Ren, J., Porta, C., Ginn, H.M., Jackson, T., PerezMartin, E., Siebert, C.A., Paul, G., Huiskonen, J.T., Jones, I.M., Esnouf, R.M., Fry, E.E., Maree, F.F., Charleston, B., Stuart, D.I.
Deposit date:2015-08-14
Release date:2015-09-23
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure-Based Energetics of Protein Interfaces Guide Foot-and-Mouth Disease Vaccine Design
Nat.Struct.Mol.Biol., 22, 2015
5ACA
  • Download 5aca
  • View 5aca
Molmil generated image of 5aca
STRUCTURE-BASED ENERGETICS OF PROTEIN INTERFACES GUIDE FOOT-AND-MOUTH DISEASE VIRUS VACCINE DESIGN
Descriptor:VP1, VP2, VP3, ...
Authors:Kotecha, A., Seago, J., Scott, K., Burman, A., Loureiro, S., Ren, J., Porta, C., Ginn, H.M., Jackson, T., Perez-Martin, E., Siebert, C.A., Paul, G., Huiskonen, J.T., Jones, I.M., Esnouf, R.M., Fry, E.E., Maree, F.F., Charleston, B., Stuart, D.I.
Deposit date:2015-08-14
Release date:2015-09-23
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure-Based Energetics of Protein Interfaces Guide Foot-and-Mouth Disease Vaccine Design
Nat.Struct.Mol.Biol., 22, 2015
5D8A
  • Download 5d8a
  • View 5d8a
Molmil generated image of 5d8a
CRYSTAL STRUCTURE OF RECOMBINANT FOOT-AND-MOUTH-DISEASE VIRUS A22-H2093F EMPTY CAPSID
Descriptor:VP1, VP2, VP3, ...
Authors:Kotecha, A., Seago, J., Scott, K., Burman, A., Loureiro, S., Ren, J., Porta, C., Ginn, H.M., Jackson, T., Perez-Martin, E., Siebert, C.A., Paul, G., Huiskonen, J.T., Jones, I.M., Esnouf, R.M., Fry, E.E., Maree, F.F., Charleston, B., Stuart, D.I.
Deposit date:2015-08-16
Release date:2015-09-23
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design.
Nat.Struct.Mol.Biol., 22, 2015
5DDJ
  • Download 5ddj
  • View 5ddj
Molmil generated image of 5ddj
CRYSTAL STRUCTURE OF RECOMBINANT FOOT-AND-MOUTH-DISEASE VIRUS O1M-S2093Y EMPTY CAPSID
Descriptor:Foot and mouth disease virus, VP1, VP2, ...
Authors:Kotecha, A., Seago, J., Scott, K., Burman, A., Loureiro, S., Ren, J., Porta, C., Ginn, H.M., Jackson, T., Perez-Martin, E., Siebert, C.A., Paul, G., Huiskonen, J.T., Jones, I.M., Esnouf, R.M., Fry, E.E., Maree, F.F., Charleston, B., Stuart, D.I.
Deposit date:2015-08-25
Release date:2015-09-23
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design.
Nat.Struct.Mol.Biol., 22, 2015
5NEM
  • Download 5nem
  • View 5nem
Molmil generated image of 5nem
LOCALISED RECONSTRUCTION OF ALPHA V BETA 6 BOUND TO FOOT AND MOUTH DISEASE VIRUS O PANASIA - POSE A.
Descriptor:O PanAsia VP1, O PanAsia VP2, O PanAsia VP3, ...
Authors:Kotecha, A., Stuart, D.
Deposit date:2017-03-10
Release date:2017-06-21
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (10.8 Å)
Cite:Rules of engagement between alpha v beta 6 integrin and foot-and-mouth disease virus.
Nat Commun, 8, 2017
5NET
  • Download 5net
  • View 5net
Molmil generated image of 5net
LOCALISED RECONSTRUCTION OF INTEGRIN ALPHA V BETA 6 BOUND TO FOOT AND MOUTH DISEASE VIRUS O1 MANISA - POSE A.
Descriptor:O1 Manisa VP1, O1 Manisa VP2, O1 Manisa VP3, ...
Authors:Kotecha, A., Stuart, D.
Deposit date:2017-03-11
Release date:2017-06-21
Last modified:2018-03-28
Method:ELECTRON MICROSCOPY (8.6 Å)
Cite:Rules of engagement between alpha v beta 6 integrin and foot-and-mouth disease virus.
Nat Commun, 8, 2017
5NE4
  • Download 5ne4
  • View 5ne4
Molmil generated image of 5ne4
CRYSTAL STRUCTURE OF FOOT AND MOUTH DISEASE VIRUS O PANASIA
Descriptor:O PanAsia VP1, O PanAsia VP2, Polyprotein, ...
Authors:Kotecha, A., StuarT, D.
Deposit date:2017-03-09
Release date:2017-06-14
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Rules of engagement between alpha v beta 6 integrin and foot-and-mouth disease virus.
Nat Commun, 8, 2017
5NED
  • Download 5ned
  • View 5ned
Molmil generated image of 5ned
CRYOEM STRUCTURE OF FOOT AND MOUTH DISEASE VIRUS O PANASIA
Descriptor:O PanAsia VP1, O PanAsia VP2, O PanAsia VP3, ...
Authors:Kotecha, A., Stuart, D.
Deposit date:2017-03-10
Release date:2017-06-21
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Rules of engagement between alpha v beta 6 integrin and foot-and-mouth disease virus.
Nat Commun, 8, 2017
5NEJ
  • Download 5nej
  • View 5nej
Molmil generated image of 5nej
CRYOEM STRUCTURE OF FOOT AND MOUTH DISEASE VIRUS O1 MANISA
Descriptor:O1 Manisa VP1, O1 Manisa VP2, O1 Manisa VP3
Authors:Kotecha, A., Stuart, D.
Deposit date:2017-03-10
Release date:2017-06-21
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Rules of engagement between alpha v beta 6 integrin and foot-and-mouth disease virus.
Nat Commun, 8, 2017
5NER
  • Download 5ner
  • View 5ner
Molmil generated image of 5ner
LOCALISED RECONSTRUCTION OF ALPHA V BETA 6 BOUND TO FOOT AND MOUTH DISEASE VIRUS O PANASIA - POSE A PRIME.
Descriptor:O PanAsia VP1, O PanAsia VP2, O PanAsia VP3, ...
Authors:Kotecha, A., Stuart, D.
Deposit date:2017-03-11
Release date:2017-06-21
Last modified:2017-10-04
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Rules of engagement between alpha v beta 6 integrin and foot-and-mouth disease virus.
Nat Commun, 8, 2017
5NEU
  • Download 5neu
  • View 5neu
Molmil generated image of 5neu
LOCALISED RECONSTRUCTION OF INTEGRIN ALPHA V BETA 6 BOUND TO FOOT AND MOUTH DISEASE VIRUS O1 MANISA - POSE B.
Descriptor:O1 Manisa VP1, O1 Manisa VP2, Capsid protein, ...
Authors:Kotecha, A., Stuart, D.
Deposit date:2017-03-11
Release date:2017-06-21
Last modified:2018-03-28
Method:ELECTRON MICROSCOPY (12.3 Å)
Cite:Rules of engagement between alpha v beta 6 integrin and foot-and-mouth disease virus.
Nat Commun, 8, 2017
5OW6
  • Download 5ow6
  • View 5ow6
Molmil generated image of 5ow6
CRYOEM STRUCTURE OF RECOMBINANT CMV PARTICLES WITH TETANUS-EPITOPE
Descriptor:VP1, Capsid protein, VP2, ...
Authors:Kotecha, A., Stuart, D.I., Backmann, M.
Deposit date:2017-08-30
Release date:2017-09-13
Last modified:2018-01-03
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer's and cat allergy.
NPJ Vaccines, 2, 2017
5OWX
  • Download 5owx
  • View 5owx
Molmil generated image of 5owx
INSIDE-OUT FMDV A10 CAPSID
Descriptor:Genome polyprotein
Authors:Kotecha, A., Malik, N., Fry, E.E., Stuart, D.I.
Deposit date:2017-09-04
Release date:2017-09-20
Last modified:2017-10-04
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation.
PLoS Pathog., 13, 2017
5OYI
  • Download 5oyi
  • View 5oyi
Molmil generated image of 5oyi
FMDV A10 DISSOCIATED PENTAMER
Descriptor:Genome polyprotein
Authors:Kotecha, A., Malik, N., Stuart, D.I.
Deposit date:2017-09-09
Release date:2017-09-20
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation.
PLoS Pathog., 13, 2017
3JB4
  • Download 3jb4
  • View 3jb4
Molmil generated image of 3jb4
STRUCTURE OF LJUNGAN VIRUS: INSIGHT INTO PICORNAVIRUS PACKAGING
Descriptor:VP1, VP0, VP3
Authors:Zhu, L., Wang, X.X., Ren, J.S., Porta, C., Wenham, H., Ekstrom, J.-O., Panjwani, A., Knowles, N.J., Kotecha, A., Siebert, A., Lindberg, M., Fry, E.E., Rao, Z.H., Tuthill, T.J., Stuart, D.I.
Deposit date:2015-07-21
Release date:2015-10-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of Ljungan virus provides insight into genome packaging of this picornavirus.
Nat Commun, 6, 2015
4IV1
  • Download 4iv1
  • View 4iv1
Molmil generated image of 4iv1
CRYSTAL STRUCTURE OF RECOMBINANT FOOT-AND-MOUTH-DISEASE VIRUS A22 EMPTY CAPSID
Descriptor:Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Porta, C., Kotecha, A., Burman, A., Jackson, T., Ren, J., Loureiro, S., Jones, I.M., Fry, E.E., Stuart, D.I., Charleston, B.
Deposit date:2013-01-22
Release date:2013-04-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.
Plos Pathog., 9, 2013
4IV3
  • Download 4iv3
  • View 4iv3
Molmil generated image of 4iv3
CRYSTAL STRUCTURE OF RECOMBINANT FOOT-AND-MOUTH-DISEASE VIRUS A22-H2093C EMPTY CAPSID
Descriptor:Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Porta, C., Kotecha, A., Burman, A., Jackson, T., Ren, J., Loureiro, S., Jones, I.M., Fry, E.E., Stuart, D.I., Charleston, B.
Deposit date:2013-01-22
Release date:2013-04-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.
Plos Pathog., 9, 2013
5M0Q
  • Download 5m0q
  • View 5m0q
Molmil generated image of 5m0q
CRYO-EM RECONSTRUCTION OF THE MAEDI-VISNA VIRUS (MVV) INTASOME
Descriptor:integrase, vDNA, non-transferred strand, ...
Authors:Ballandras-Colas, A., Maskell, D., Pye, V.E., Locke, J., Swuec, S., Kotecha, A., Costa, A., Cherepanov, P.
Deposit date:2016-10-05
Release date:2017-01-18
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (4.91 Å)
Cite:A supramolecular assembly mediates lentiviral DNA integration.
Science, 355, 2017
5M0R
  • Download 5m0r
  • View 5m0r
Molmil generated image of 5m0r
CRYO-EM RECONSTRUCTION OF THE MAEDI-VISNA VIRUS (MVV) STRAND TRANSFER COMPLEX
Descriptor:integrase, vDNA, non-transfered strand, ...
Authors:Pye, V.E., Ballandras-Colas, A., Maskell, D., Locke, J., Kotecha, A., Costa, A., Cherepanov, P.
Deposit date:2016-10-05
Release date:2017-01-18
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:A supramolecular assembly mediates lentiviral DNA integration.
Science, 355, 2017
5OSN
  • Download 5osn
  • View 5osn
Molmil generated image of 5osn
CRYSTAL STRUCTURE OF BOVINE ENTEROVIRUS 2 DETERMINED WITH SERIAL FEMTOSECOND X-RAY CRYSTALLOGRAPHY
Descriptor:Capsid protein, SPHINGOSINE, POTASSIUM ION, ...
Authors:Roedig, P., Ginn, H.M., Pakendorf, T., Sutton, G., Harlos, K., Walter, T.S., Meyer, J., Fischer, P., Duman, R., Vartiainen, I., Reime, B., Warmer, M., Brewster, A.S., Young, I.D., Michels-Clark, T., Sauter, N.K., Kotecha, A., Kelly, J., Rowlands, D.J., Sikorsky, M., Nelson, S., Damiani, D.S., Alonso-Mori, R., Ren, J., Fry, E.E., David, C., Stuart, D.I., Wagner, A., Meents, A.
Deposit date:2017-08-17
Release date:2017-08-30
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:High-speed fixed-target serial virus crystallography.
Nat. Methods, 14, 2017
5FJ5
  • Download 5fj5
  • View 5fj5
Molmil generated image of 5fj5
STRUCTURE OF THE IN VITRO ASSEMBLED BACTERIOPHAGE PHI6 POLYMERASE COMPLEX
Descriptor:MAJOR INNER PROTEIN P1
Authors:Ilca, S., Kotecha, A., Sun, X., Poranen, M.P., Stuart, D.I., Huiskonen, J.T.
Deposit date:2015-10-06
Release date:2015-11-04
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes.
Nat.Commun., 6, 2015
5FJ6
  • Download 5fj6
  • View 5fj6
Molmil generated image of 5fj6
STRUCTURE OF THE P2 POLYMERASE INSIDE IN VITRO ASSEMBLED BACTERIOPHAGE PHI6 POLYMERASE COMPLEX
Descriptor:RNA-DIRECTED RNA POLYMERASE, MANGANESE (II) ION
Authors:Ilca, S., Kotecha, A., Sun, X., Poranen, M.P., Stuart, D.I., Huiskonen, J.T.
Deposit date:2015-10-06
Release date:2015-11-04
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes.
Nat.Commun., 6, 2015
5FJ7
  • Download 5fj7
  • View 5fj7
Molmil generated image of 5fj7
STRUCTURE OF THE P2 POLYMERASE INSIDE IN VITRO ASSEMBLED BACTERIOPHAGE PHI6 POLYMERASE COMPLEX, WITH P1 INCLUDED
Descriptor:MAJOR INNER PROTEIN P1, RNA-DIRECTED RNA POLYMERASE, MANGANESE (II) ION
Authors:Ilca, S., Kotecha, A., Sun, X., Poranen, M.P., Stuart, D.I., Huiskonen, J.T.
Deposit date:2015-10-06
Release date:2015-11-04
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes.
Nat.Commun., 6, 2015
5MUU
  • Download 5muu
  • View 5muu
Molmil generated image of 5muu
DSRNA BACTERIOPHAGE PHI6 NUCLEOCAPSID
Descriptor:Major inner protein P1, Packaging enzyme P4, Major outer capsid protein
Authors:Sun, Z., El Omari, K., Sun, X., Ilca, S.L., Kotecha, A., Stuart, D.I., Poranen, M.M., Huiskonen, J.T.
Deposit date:2017-01-14
Release date:2017-03-22
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Double-stranded RNA virus outer shell assembly by bona fide domain-swapping.
Nat Commun, 8, 2017
5MUV
  • Download 5muv
  • View 5muv
Molmil generated image of 5muv
ATOMIC STRUCTURE FITTED INTO A LOCALIZED RECONSTRUCTION OF BACTERIOPHAGE PHI6 PACKAGING HEXAMER P4
Descriptor:Packaging enzyme P4, CALCIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Sun, Z., El Omari, K., Sun, X., Ilca, S., Kotecha, A., Stuart, D.I., Poranen, M.M., Huiskonen, J.T.
Deposit date:2017-01-14
Release date:2017-03-22
Last modified:2019-04-24
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Double-stranded RNA virus outer shell assembly by bona fide domain-swapping.
Nat Commun, 8, 2017
<12>