Author results

1DFJ
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RIBONUCLEASE INHIBITOR COMPLEXED WITH RIBONUCLEASE A
Descriptor:RIBONUCLEASE A, RIBONUCLEASE INHIBITOR, SULFATE ION
Authors:Kobe, B., Deisenhofer, J.
Deposit date:1996-06-29
Release date:1997-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A structural basis of the interactions between leucine-rich repeats and protein ligands.
Nature, 374, 1995
2BNH
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PORCINE RIBONUCLEASE INHIBITOR
Descriptor:RIBONUCLEASE INHIBITOR
Authors:Kobe, B., Deisenhofer, J.
Deposit date:1996-06-29
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of ribonuclease inhibition by ribonuclease inhibitor protein based on the crystal structure of its complex with ribonuclease A.
J.Mol.Biol., 264, 1996
1IAL
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IMPORTIN ALPHA, MOUSE
Descriptor:IMPORTIN ALPHA
Authors:Kobe, B.
Deposit date:1999-01-12
Release date:1999-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin alpha.
Nat.Struct.Biol., 6, 1999
1KOA
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TWITCHIN KINASE FRAGMENT (C.ELEGANS), AUTOREGULATED PROTEIN KINASE AND IMMUNOGLOBULIN DOMAINS
Descriptor:TWITCHIN
Authors:Kobe, B., Heierhorst, J., Feil, S.C., Parker, M.W., Benian, G.M., Weiss, K.R., Kemp, B.E.
Deposit date:1996-06-28
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Giant protein kinases: domain interactions and structural basis of autoregulation.
EMBO J., 15, 1996
1KOB
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TWITCHIN KINASE FRAGMENT (APLYSIA), AUTOREGULATED PROTEIN KINASE DOMAIN
Descriptor:TWITCHIN, VALINE
Authors:Kobe, B., Heierhorst, J., Feil, S.C., Parker, M.W., Benian, G.M., Weiss, K.R., Kemp, B.E.
Deposit date:1996-06-28
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Giant protein kinases: domain interactions and structural basis of autoregulation.
EMBO J., 15, 1996
1MG1
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HTLV-1 GP21 ECTODOMAIN/MALTOSE-BINDING PROTEIN CHIMERA
Descriptor:PROTEIN (HTLV-1 GP21 ECTODOMAIN/MALTOSE-BINDING PROTEIN CHIMERA), MALTOSE, CHLORIDE ION
Authors:Kobe, B., Center, R.J., Kemp, B.E., Poumbourios, P.
Deposit date:1999-03-01
Release date:1999-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human T cell leukemia virus type 1 gp21 ectodomain crystallized as a maltose-binding protein chimera reveals structural evolution of retroviral transmembrane proteins.
Proc.Natl.Acad.Sci.USA, 96, 1999
1PHZ
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STRUCTURE OF PHOSPHORYLATED PHENYLALANINE HYDROXYLASE
Descriptor:PROTEIN (PHENYLALANINE HYDROXYLASE), FE (III) ION
Authors:Kobe, B., Jennings, I.G., House, C.M., Michell, B.J., Cotton, R.G., Kemp, B.E.
Deposit date:1998-11-11
Release date:1999-04-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of autoregulation of phenylalanine hydroxylase.
Nat.Struct.Biol., 6, 1999
2PHM
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STRUCTURE OF PHENYLALANINE HYDROXYLASE DEPHOSPHORYLATED
Descriptor:PROTEIN (PHENYLALANINE-4-HYDROXYLASE), FE (III) ION
Authors:Kobe, B., Jennings, I.G., House, C.M., Michell, B.J., Cotton, R.G., Kemp, B.E.
Deposit date:1998-11-11
Release date:1999-04-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of autoregulation of phenylalanine hydroxylase.
Nat.Struct.Biol., 6, 1999
1PJM
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MOUSE IMPORTIN ALPHA-BIPARTITE NLS FROM HUMAN RETINOBLASTOMA PROTEIN COMPLEX
Descriptor:Retinoblastoma-associated protein, Importin alpha-2 subunit
Authors:Fontes, M.R.M., Teh, T., Jans, D., Brinkworth, R.I., Kobe, B.
Deposit date:2003-06-03
Release date:2003-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha
J.Biol.Chem., 278, 2003
1PJN
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MOUSE IMPORTIN ALPHA-BIPARTITE NLS N1N2 FROM XENOPUS LAEVIS PHOSPHOPROTEIN COMPLEX
Descriptor:Histone-binding protein N1/N2, Importin alpha-2 subunit
Authors:Fontes, M.R.M., Teh, T., Jans, D., Brinkworth, R.I., Kobe, B.
Deposit date:2003-06-03
Release date:2003-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha
J.Biol.Chem., 278, 2003
1EJL
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MOUSE IMPORTIN ALPHA-SV40 LARGE T ANTIGEN NLS PEPTIDE COMPLEX
Descriptor:SV40 LARGE T ANTIGEN NLS PEPTIDE, IMPORTIN ALPHA
Authors:Fontes, M.R., Teh, T., Kobe, B.
Deposit date:2000-03-03
Release date:2000-04-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha.
J.Mol.Biol., 297, 2000
1EJY
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MOUSE IMPORTIN ALPHA-NUCLEOPLASMIN NLS PEPTIDE COMPLEX
Descriptor:NUCLEOPLASMIN NLS PEPTIDE, IMPORTIN ALPHA
Authors:Fontes, M.R., Teh, T., Kobe, B.
Deposit date:2000-03-05
Release date:2000-04-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha.
J.Mol.Biol., 297, 2000
1Q1S
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MOUSE IMPORTIN ALPHA- PHOSPHORYLATED SV40 CN PEPTIDE COMPLEX
Descriptor:Large T antigen, Importin alpha-2 subunit
Authors:Fontes, M.R.M., Teh, T., Toth, G., John, A., Pavo, I., Jans, D.A., Kobe, B.
Deposit date:2003-07-22
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
1Q1T
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MOUSE IMPORTIN ALPHA: NON-PHOSPHORYLATED SV40 CN PEPTIDE COMPLEX
Descriptor:Large T antigen, Importin alpha-2 subunit
Authors:Fontes, M.R.M., Teh, T., Toth, G., John, A., Pavo, I., Jans, D.A., Kobe, B.
Deposit date:2003-07-22
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
3ZK7
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CRYSTAL STRUCTURE OF PNEUMOCOCCAL SURFACE ANTIGEN PSAA IN THE METAL-FREE, OPEN STATE
Descriptor:MANGANESE ABC TRANSPORTER SUBSTRATE-BINDING LIPOPROTEIN, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Counago, R.M., Ween, M.P., Bajaj, M., Zuegg, J., Cooper, M.A., McEwan, A.G., Paton, J.C., Kobe, B., McDevitt, C.A.
Deposit date:2013-01-22
Release date:2013-11-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Imperfect coordination chemistry facilitates metal ion release in the Psa permease.
Nat. Chem. Biol., 10, 2014
3ZK8
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CRYSTAL STRUCTURE OF PNEUMOCOCCAL SURFACE ANTIGEN PSAA E205Q IN THE METAL-FREE, OPEN STATE
Descriptor:MANGANESE ABC TRANSPORTER SUBSTRATE-BINDING LIPOPROTEIN, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Counago, R.M., Ween, M.P., Bajaj, M., Zuegg, J., Cooper, M.A., McEwan, A.G., Paton, J.C., Kobe, B., McDevitt, C.A.
Deposit date:2013-01-22
Release date:2013-11-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Imperfect coordination chemistry facilitates metal ion release in the Psa permease.
Nat. Chem. Biol., 10, 2014
3ZK9
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CRYSTAL STRUCTURE OF PNEUMOCOCCAL SURFACE ANTIGEN PSAA D280N IN THE METAL-FREE, OPEN STATE
Descriptor:MANGANESE ABC TRANSPORTER SUBSTRATE-BINDING LIPOPROTEIN, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Counago, R.M., Ween, M.P., Bajaj, M., Zuegg, J., Cooper, M.A., McEwan, A.G., Paton, J.C., Kobe, B., McDevitt, C.A.
Deposit date:2013-01-22
Release date:2013-11-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Imperfect coordination chemistry facilitates metal ion release in the Psa permease.
Nat. Chem. Biol., 10, 2014
3ZKA
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CRYSTAL STRUCTURE OF PNEUMOCOCCAL SURFACE ANTIGEN PSAA D280N IN THE METAL-BOUND, OPEN STATE
Descriptor:MANGANESE ABC TRANSPORTER SUBSTRATE-BINDING LIPOPROTEIN, MANGANESE (II) ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Counago, R.M., Ween, M.P., Bajaj, M., Zuegg, J., Cooper, M.A., McEwan, A.G., Paton, J.C., Kobe, B., McDevitt, C.A.
Deposit date:2013-01-22
Release date:2013-11-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Imperfect coordination chemistry facilitates metal ion release in the Psa permease.
Nat. Chem. Biol., 10, 2014
4BJM
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CRYSTAL STRUCTURE OF THE FLAX-RUST EFFECTOR AVRM
Descriptor:AVRM, CHLORIDE ION
Authors:Ve, T., Williams, S.J., Kobe, B.
Deposit date:2013-04-19
Release date:2013-10-16
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of the Flax-Rust Effector Avrm Reveal Insights Into the Molecular Basis of Plant-Cell Entry and Effector-Triggered Immunity
Proc.Natl.Acad.Sci.USA, 110, 2013
4BJN
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CRYSTAL STRUCTURE OF THE FLAX-RUST EFFECTOR AVRM-A
Descriptor:AVRM-A
Authors:Ve, T., Williams, S.J., Kobe, B.
Deposit date:2013-04-19
Release date:2013-10-16
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of the Flax-Rust Effector Avrm Reveal Insights Into the Molecular Basis of Plant-Cell Entry and Effector-Triggered Immunity
Proc.Natl.Acad.Sci.USA, 110, 2013
5TEC
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CRYSTAL STRUCTURE OF THE TIR DOMAIN FROM THE ARABIDOPSIS THALIANA NLR PROTEIN SNC1
Descriptor:Protein SUPPRESSOR OF npr1-1, CONSTITUTIVE 1
Authors:Zhang, X., Bentham, A., Ve, T., Williams, S.J., Kobe, B.
Deposit date:2016-09-20
Release date:2017-02-01
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Multiple functional self-association interfaces in plant TIR domains.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VJJ
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CRYSTAL STRUCTURE OF THE FLAX-RUST EFFECTOR AVRP
Descriptor:Avirulence protein AvrP123, ZINC ION
Authors:Zhang, X., Ericsson, D.J., Williams, S.J., Kobe, B.
Deposit date:2017-04-19
Release date:2017-08-30
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Crystal structure of the Melampsora lini effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein P.
Mol. Plant Pathol., 19, 2018
1IQ1
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CRYSTAL STRUCTURE OF THE IMPORTIN-ALPHA(44-54)-IMPORTIN-ALPHA(70-529) COMPLEX
Descriptor:IMPORTIN ALPHA-2 SUBUNIT
Authors:Catimel, B., Teh, T., Fontes, M.R.M., Jennings, I.G., Kobe, B.
Deposit date:2001-05-28
Release date:2001-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Biophysical characterization of interactions involving importin-alpha during nuclear import.
J.Biol.Chem., 276, 2001
4BOF
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CRYSTAL STRUCTURE OF ARGININE DEIMINASE FROM GROUP A STREPTOCOCCUS
Descriptor:ARGININE DEIMINASE, SULFATE ION, TRIETHYLENE GLYCOL, ...
Authors:Henningham, A., Ericsson, D.J., Langer, K., Casey, L., Jovcevski, B., Chhatwal, G.S., Aquilina, J.A., Batzloff, M.R., Kobe, B., Walker, M.J.
Deposit date:2013-05-20
Release date:2013-08-21
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structure-informed design of an enzymatically inactive vaccine component for group A Streptococcus.
MBio, 4, 2013
5UZB
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CRYO-EM STRUCTURE OF THE MAL TIR DOMAIN FILAMENT
Descriptor:Toll/interleukin-1 receptor domain-containing adapter protein
Authors:Ve, T., Vajjhala, P.R., Hedger, A., Croll, T., DiMaio, F., Horsefield, S., Yu, X., Lavrencic, P., Hassan, Z., Morgan, G.P., Mansell, A., Mobli, M., O'Carrol, A., Chauvin, B., Gambin, Y., Sierecki, E., Landsberg, M.J., Stacey, K.J., Egelman, E.H., Kobe, B.
Deposit date:2017-02-25
Release date:2017-07-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling.
Nat. Struct. Mol. Biol., 24, 2017