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3MDD
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BU of 3mdd by Molmil
CRYSTAL STRUCTURES OF MEDIUM CHAIN ACYL-COA DEHYDROGENASE FROM PIG LIVER MITOCHONDRIA WITH AND WITHOUT SUBSTRATE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, MEDIUM CHAIN ACYL-COA DEHYDROGENASE
Authors:Kim, J.-J.P, Wang, M, Paschke, R.
Deposit date:1994-07-13
Release date:1994-09-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate.
Proc.Natl.Acad.Sci.USA, 90, 1993
3MDE
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BU of 3mde by Molmil
CRYSTAL STRUCTURES OF MEDIUM CHAIN ACYL-COA DEHYDROGENASE FROM PIG LIVER MITOCHONDRIA WITH AND WITHOUT SUBSTRATE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, MEDIUM CHAIN ACYL-COA DEHYDROGENASE, OCTANOYL-COENZYME A
Authors:Kim, J.-J.P, Wang, M, Paschke, R.
Deposit date:1994-07-13
Release date:1994-09-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate.
Proc.Natl.Acad.Sci.USA, 90, 1993
2NYQ
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BU of 2nyq by Molmil
Structure of Vibrio proteolyticus aminopeptidase with a bound Trp fragment of dLWCF
Descriptor: Aminopeptidase, Tetrapeptide, ZINC ION
Authors:Bennett, B, Kumar, A, Narayanan, B, Kim, J.-J.
Deposit date:2006-11-21
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Substrate recognition by the leucine aminopeptidase from Vibrio proteolyticus
To be Published
2IQ6
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BU of 2iq6 by Molmil
Crystal Structure of the Aminopeptidase from Vibrio proteolyticus in Complexation with Leucyl-leucyl-leucine.
Descriptor: Bacterial leucyl aminopeptidase, Peptide, (Leucyl-leucyl-leucine), ...
Authors:Kumar, A, Narayanan, B, Kim, J.-J.P, Bennett, B.
Deposit date:2006-10-13
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Experimental evidence for a metallohydrolase mechanism in which the nucleophile is not delivered by a metal ion: EPR spectrokinetic and structural studies of aminopeptidase from Vibrio proteolyticus
Biochem.J., 403, 2007
2CW6
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BU of 2cw6 by Molmil
Crystal Structure of Human HMG-CoA Lyase: Insights into Catalysis and the Molecular Basis for Hydroxymethylglutaric Aciduria
Descriptor: 3-HYDROXYPENTANEDIOIC ACID, Hydroxymethylglutaryl-CoA lyase, mitochondrial, ...
Authors:Fu, Z, Runquist, J.A, Hunt, J.F, Miziorko, H.M, Kim, J.-J.P.
Deposit date:2005-06-17
Release date:2005-12-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human 3-hydroxy-3-methylglutaryl-CoA Lyase: insights into catalysis and the molecular basis for hydroxymethylglutaric aciduria
J.Biol.Chem., 281, 2006
2G7N
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BU of 2g7n by Molmil
Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to small Molecule Inhibitors
Descriptor: Botulinum neurotoxin type A, SILVER ION, ZINC ION
Authors:Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Light Chain of Botulinum Neurotoxin Serotype A bound to Small Molecule Inhibitors
To be Published
1SYO
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BU of 1syo by Molmil
N-terminal 3 domains of CI-MPR bound to mannose 6-phosphate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-alpha-D-mannopyranose, GLYCEROL, ...
Authors:Olson, L.J, Dahms, N.M, Kim, J.-J.P.
Deposit date:2004-04-01
Release date:2004-06-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The N-terminal carbohydrate recognition site of the cation-independent mannose 6-phosphate receptor
J.Biol.Chem., 279, 2004
1Q25
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BU of 1q25 by Molmil
Crystal structure of N-terminal 3 domains of CI-MPR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Olson, L.J, Dahms, N.M, Kim, J.-J.P.
Deposit date:2003-07-23
Release date:2004-06-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of uPAR, plasminogen, and sugar-binding sites of the 300 kDa mannose 6-phosphate receptor
Embo J., 23, 2004
1SZ0
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BU of 1sz0 by Molmil
N-terminal 3 domains of CI-MPR bound to mannose 6-phosphate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Olson, L.J, Dahms, N.M, Kim, J.-J.P.
Deposit date:2004-04-01
Release date:2004-06-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The N-terminal carbohydrate recognition site of the cation-independent mannose 6-phosphate receptor
J.Biol.Chem., 279, 2004
1XX4
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BU of 1xx4 by Molmil
Crystal Structure of Rat Mitochondrial 3,2-Enoyl-CoA
Descriptor: 3,2-trans-enoyl-CoA isomerase, mitochondrial, BENZAMIDINE, ...
Authors:Hubbard, P.A, Yu, W, Schulz, H, Kim, J.-J.
Deposit date:2004-11-03
Release date:2004-11-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Domain swapping in the low-similarity isomerase/hydratase superfamily: the crystal structure of rat mitochondrial Delta3, Delta2-enoyl-CoA isomerase.
Protein Sci., 14, 2005
3ES9
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BU of 3es9 by Molmil
NADPH-Cytochrome P450 Reductase in an Open Conformation
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Hamdane, D, Xia, C, Im, S.-C, Zhang, H, Kim, J.-J, Waskell, L.
Deposit date:2008-10-05
Release date:2009-01-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure and function of an NADPH-cytochrome P450 oxidoreductase in an open conformation capable of reducing cytochrome P450
J.Biol.Chem., 284, 2009
6P8I
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BU of 6p8i by Molmil
N-terminal 5 domains of IGFIIR
Descriptor: Cation-independent mannose-6-phosphate receptor, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Olson, L.J, Dahms, N.M, Kim, J.-J.P.
Deposit date:2019-06-07
Release date:2020-06-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor.
Commun Biol, 3, 2020
3RMY
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BU of 3rmy by Molmil
Crystal structure of HCR/D W1238A mutant
Descriptor: Botulinum neurotoxin type D, GLYCEROL
Authors:Fu, Z, Karalewitz, A, Kroken, A, Kim, J.-J.P, Barbieri, J.T.
Deposit date:2011-04-21
Release date:2011-06-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Novel Ganglioside-mediated Entry of Botulinum Neurotoxin Serotype D into Neurons.
J.Biol.Chem., 286, 2011
3RSJ
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BU of 3rsj by Molmil
Structure of HCRF in complex with Ganglioside GD1a
Descriptor: BoNT/F, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose, ...
Authors:Fu, Z, Benson, M.A, Barbieri, J.T, Kim, J.-J.P, Baldwin, M.R.
Deposit date:2011-05-02
Release date:2011-08-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Unique ganglioside recognition strategies for clostridial neurotoxins.
J.Biol.Chem., 286, 2011
4XQM
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BU of 4xqm by Molmil
Crystal structure of the MRH domain of Glucosidase II beta bound to mannose
Descriptor: Glucosidase 2 subunit beta, alpha-D-mannopyranose
Authors:Olson, L.J, Dahms, N.M, Kim, J.-J.P.
Deposit date:2015-01-19
Release date:2015-07-22
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.625 Å)
Cite:Crystal Structure and Functional Analyses of the Lectin Domain of Glucosidase II: Insights into Oligomannose Recognition.
Biochemistry, 54, 2015
1KEO
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BU of 1keo by Molmil
TWISTS AND TURNS OF THE CD-MPR: LIGAND-BOUND VERSUS LIGAND-FREE RECEPTOR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, cation-dependent mannose-6-phosphate receptor
Authors:Olson, L.J, Zhang, J, Dahms, N.M, Kim, J.J.
Deposit date:2001-11-16
Release date:2002-01-23
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Twists and turns of the cation-dependent mannose 6-phosphate receptor. Ligand-bound versus ligand-free receptor
J.Biol.Chem., 277, 2002
6V02
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BU of 6v02 by Molmil
N-terminal 5 domains of CI-MPR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cation-independent mannose-6-phosphate receptor
Authors:Olson, L.J, Dahms, N.M, Kim, J.-J.P.
Deposit date:2019-11-18
Release date:2020-09-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor.
Commun Biol, 3, 2020
4FVV
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BU of 4fvv by Molmil
Crystal structure of HCR/D-Sa-GBL1/C
Descriptor: GLYCEROL, N-acetyl-alpha-neuraminic acid, Neurotoxin, ...
Authors:Fu, Z, Karalewitz, A, Baldwin, M.R, Kim, J.-J.P, Barbieri, J.T.
Deposit date:2012-06-29
Release date:2012-10-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry.
J.Biol.Chem., 287, 2012
3MP4
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BU of 3mp4 by Molmil
Crystal structure of Human lyase R41M mutant
Descriptor: Hydroxymethylglutaryl-CoA lyase
Authors:Fu, Z, Runquist, J.A, Montgomery, C, Miziorko, H.M, Kim, J.-J.P.
Deposit date:2010-04-24
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
3MP3
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BU of 3mp3 by Molmil
Crystal Structure of Human Lyase in complex with inhibitor HG-CoA
Descriptor: (3R,5S,9R,21S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,21-tetrahydroxy-8,8-dimethyl-10,14,19-trioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide, 3-HYDROXYPENTANEDIOIC ACID, Hydroxymethylglutaryl-CoA lyase, ...
Authors:Fu, Z, Runquist, J.A, Montgomery, C, Miziorko, H.M, Kim, J.-J.P.
Deposit date:2010-04-24
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
3MP5
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BU of 3mp5 by Molmil
Crystal Structure of Human Lyase R41M in complex with HMG-CoA
Descriptor: 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, Hydroxymethylglutaryl-CoA lyase, MAGNESIUM ION
Authors:Fu, Z, Runquist, J.A, Montgomery, C, Miziorko, H.M, Kim, J.-J.P.
Deposit date:2010-04-24
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
3HN1
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BU of 3hn1 by Molmil
Crystal structure of HCR/T complexed with GT2 and lactose
Descriptor: N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid, SULFATE ION, Tetanus toxin, ...
Authors:Chen, C, Fu, Z, Kim, J.-J.P, Barbieri, J.T, Baldwin, M.R.
Deposit date:2009-05-29
Release date:2009-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Gangliosides as high affinity receptors for tetanus neurotoxin.
J.Biol.Chem., 284, 2009
3HMY
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BU of 3hmy by Molmil
Crystal structure of HCR/T complexed with GT2
Descriptor: GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid, SULFATE ION, ...
Authors:Chen, C, Fu, Z, Kim, J.-J.P, Barbieri, J.T, Baldwin, M.R.
Deposit date:2009-05-29
Release date:2009-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Gangliosides as high affinity receptors for tetanus neurotoxin.
J.Biol.Chem., 284, 2009
2RL9
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BU of 2rl9 by Molmil
Crystal Structure cation-dependent mannose 6-phosphate receptor at pH 6.5 bound to trimannoside
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, Cation-dependent mannose-6-phosphate receptor, ...
Authors:Olson, L.J, Hindsgaul, O, Dahms, N.M, Kim, J.-J.P.
Deposit date:2007-10-18
Release date:2008-02-12
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into the mechanism of pH-dependent ligand binding and release by the cation-dependent mannose 6-phosphate receptor.
J.Biol.Chem., 283, 2008
2RL7
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Crystal Structure cation-dependent mannose 6-phosphate receptor at pH 4.8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CACODYLATE ION, ...
Authors:Olson, L.J, Hindsgaul, O, Kim, J.-J.P, Dahms, N.M.
Deposit date:2007-10-18
Release date:2008-02-12
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor.
J.Biol.Chem., 283, 2008

 

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