Author results

1CVX
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CRYSTAL STRUCTURE OF POLYAMIDE DIMER (IMPYHPPYBETADP)2 BOUND TO B-DNA DECAMER CCAGATCTGG
Descriptor:5'-D(*CP*CP*AP*GP*AP*TP*CP*TP*GP*G)-3', HYDROXYPYRROLE-IMIDAZOLE-PYRROLE POLYAMIDE
Authors:Kielkopf, C.L., Bremer, R.E., White, S., Baird, E.E., Dervan, P.B., Rees, D.C.
Deposit date:1999-08-24
Release date:2000-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove.
J.Mol.Biol., 295, 2000
1CVY
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CRYSTAL STRUCTURE OF POLYAMIDE DIMER (IMPYPYPYBETADP)2 BOUND TO CCAGATCTGG
Descriptor:5'-D(*CP*CP*AP*GP*AP*TP*CP*TP*GP*G)-3', IMIDAZOLE-PYRROLE POLYAMIDE
Authors:Kielkopf, C.L., Bremer, R.E., White, S., Baird, E.E., Dervan, P.B., Rees, D.C.
Deposit date:1999-08-24
Release date:2000-01-15
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove.
J.Mol.Biol., 295, 2000
1D8G
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ULTRAHIGH RESOLUTION CRYSTAL STRUCTURE OF B-DNA DECAMER D(CCAGTACTGG)
Descriptor:5'-D(*CP*CP*AP*GP*TP*AP*CP*TP*GP*GP*)-3', CALCIUM ION
Authors:Kielkopf, C.L., Ding, S., Kuhn, P., Rees, D.C.
Deposit date:1999-10-23
Release date:2000-02-21
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (0.74 Å)
Cite:Conformational flexibility of B-DNA at 0.74 A resolution: d(CCAGTACTGG)(2).
J.Mol.Biol., 296, 2000
1JG8
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CRYSTAL STRUCTURE OF THREONINE ALDOLASE (LOW-SPECIFICITY)
Descriptor:L-allo-threonine aldolase, CALCIUM ION, SODIUM ION
Authors:Kielkopf, C.L., Bonanno, J., Ray, S., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-06-23
Release date:2001-07-04
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Low-specificity Threonine Aldolase, a Key Enzyme in Glycine Biosynthesis
To be published
1JMT
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X-RAY STRUCTURE OF A CORE U2AF65/U2AF35 HETERODIMER
Descriptor:SPLICING FACTOR U2AF 35 KDA SUBUNIT, SPLICING FACTOR U2AF 65 KDA SUBUNIT, HEXANE-1,6-DIOL
Authors:Kielkopf, C.L., Rodionova, N.A., Green, M.R., Burley, S.K.
Deposit date:2001-07-19
Release date:2001-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer.
Cell(Cambridge,Mass.), 106, 2001
1LW4
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X-RAY STRUCTURE OF L-THREONINE ALDOLASE (LOW-SPECIFICITY) IN COMPLEX WITH L-ALLO-THREONINE
Descriptor:L-allo-threonine aldolase, CALCIUM ION, CHLORIDE ION, ...
Authors:Kielkopf, C.L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2002-05-30
Release date:2002-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray Structures of Threonine Aldolase Complexes: Structural Basis of Substrate Recognition
Biochemistry, 41, 2002
1LW5
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X-RAY STRUCTURE OF L-THREONINE ALDOLASE (LOW-SPECIFICITY) IN COMPLEX WITH GLYCINE
Descriptor:L-allo-threonine aldolase, CALCIUM ION, CHLORIDE ION, ...
Authors:Kielkopf, C.L., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2002-05-30
Release date:2002-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:X-ray Structures of Threonine Aldolase Complexes: Structural Basis of Substrate Recognition
Biochemistry, 41, 2002
365D
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STRUCTURAL BASIS FOR G C RECOGNITION IN THE DNA MINOR GROOVE
Descriptor:DNA (5'-D(*CP*CP*AP*GP*GP*(CBR)P*CP*TP*GP*G)-3'), IMIDAZOLE-PYRROLE POLYAMIDE
Authors:Kielkopf, C.L., Baird, E.E., Dervan, P.B., Rees, D.C.
Deposit date:1997-12-17
Release date:1998-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for G.C recognition in the DNA minor groove.
Nat.Struct.Biol., 5, 1998
408D
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STRUCTURAL BASIS FOR RECOGNITION OF A-T AND T-A BASE PAIRS IN THE MINOR GROOVE OF B-DNA
Descriptor:DNA (5'-D(*CP*CP*AP*GP*TP*AP*CP*TP*GP*G)-3'), IMIDAZOLE-PYRROLE POLYAMIDE
Authors:Kielkopf, C.L., White, S., Szewczyk, J.W., Turner, J.M., Baird, E.E., Dervan, P.B., Rees, D.C.
Deposit date:1998-06-24
Release date:1998-10-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA.
Science, 282, 1998
454D
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INTERCALATION AND MAJOR GROOVE RECOGNITION IN THE 1.2 A RESOLUTION CRYSTAL STRUCTURE OF RH[ME2TRIEN]PHI BOUND TO 5'-G(5IU)TGCAAC-3'
Descriptor:5'-D(*GP*(5IU)P*TP*GP*CP*AP*AP*C)-3', DELTA-ALPHA-RH[2R,9R-DIAMINO-4,7-DIAZADECANE]9,10-PHENANTHRENEQUINONE DIIMINE
Authors:Kielkopf, C.L., Erkkila, K.E., Hudson, B.P., Barton, J.K., Rees, D.C.
Deposit date:1999-03-03
Release date:2000-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure of a photoactive rhodium complex intercalated into DNA.
Nat.Struct.Biol., 7, 2000
1M6S
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CRYSTAL STRUCTURE OF THREONINE ALDOLASE
Descriptor:L-allo-threonine aldolase, CALCIUM ION, CHLORIDE ION
Authors:Burley, S.K., Kielkopf, C.L.
Deposit date:2002-07-17
Release date:2002-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray Structures of Threonine Aldolase Complexes: Structural Basis of Substrate Recognition
Biochemistry, 41, 2002
2G4B
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STRUCTURE OF U2AF65 VARIANT WITH POLYURIDINE TRACT
Descriptor:5'-R(P*UP*UP*UP*UP*UP*UP*U)-3', Splicing factor U2AF 65 kDa subunit, 1,4-DIETHYLENE DIOXIDE
Authors:Sickmier, E.A., Kielkopf, C.L.
Deposit date:2006-02-21
Release date:2006-07-25
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of polypyrimidine tract recognition by the essential splicing factor U2AF65.
Mol.Cell, 23, 2006
2HZC
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CRYSTAL STRUCTURE OF THE N-TERMINAL RRM OF THE U2AF LARGE SUBUNIT
Descriptor:Splicing factor U2AF 65 kDa subunit, ZINC ION, HEXAETHYLENE GLYCOL
Authors:Thickman, K.R., Sickmier, E.A., Kielkopf, C.L.
Deposit date:2006-08-08
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Alternative Conformations at the RNA-binding Surface of the N-terminal U2AF(65) RNA Recognition Motif.
J.Mol.Biol., 366, 2007
1XCB
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X-RAY STRUCTURE OF A REX-FAMILY REPRESSOR/NADH COMPLEX FROM THERMUS AQUATICUS
Descriptor:Redox-sensing transcriptional repressor rex, CALCIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Sickmier, E.A., Brekasis, D., Paranawithana, S., Bonanno, J.B., Burley, S.K., Paget, M.S., Kielkopf, C.L., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-09-01
Release date:2004-09-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:X-Ray Structure of a Rex-Family Repressor/NADH Complex: Insights into the Mechanism of Redox Sensing
Structure, 13, 2005
2OKS
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X-RAY STRUCTURE OF A DNA REPAIR SUBSTRATE CONTAINING AN ALKYL INTERSTRAND CROSSLINK AT 1.65 RESOLUTION
Descriptor:5'-D(*CP*CP*AP*AP*(C34)P*GP*TP*TP*GP*G)-3', CALCIUM ION
Authors:Swenson, M.C., Paranawithana, S.R., Miller, P.S., Kielkopf, C.L.
Deposit date:2007-01-17
Release date:2007-02-13
Last modified:2017-01-11
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of a DNA repair substrate containing an alkyl interstrand cross-link at 1.65 a resolution.
Biochemistry, 46, 2007
3BS9
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X-RAY STRUCTURE OF HUMAN TIA-1 RRM2
Descriptor:Nucleolysin TIA-1 isoform p40, IODIDE ION
Authors:Kumar, A.O., Kielkopf, C.L.
Deposit date:2007-12-22
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of the central RNA recognition motif of human TIA-1 at 1.95A resolution.
Biochem.Biophys.Res.Commun., 367, 2008
3CGP
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X-RAY STRUCTURE OF A PSEUDOURIDINE-CONTAINING YEAST SPLICEOSOMAL U2 SNRNA-INTRON BRANCH SITE DUPLEX BOUND TO IODIDE IONS
Descriptor:RNA (5'-R(*GP*CP*GP*CP*GP*(PSU)P*AP*GP*UP*AP*GP*C)-3'), RNA (5'-R(*CP*GP*CP*UP*AP*CP*UP*AP*AP*CP*GP*CP*G)-3'), SULFATE ION, ...
Authors:Lin, Y., Kielkopf, C.L.
Deposit date:2008-03-06
Release date:2008-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.
Biochemistry, 47, 2008
3CGQ
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X-RAY STRUCTURE OF A PSEUDOURIDINE-CONTAINING YEAST SPLICEOSOMAL U2 SNRNA-INTRON BRANCH SITE DUPLEX
Descriptor:RNA (5'-R(*GP*CP*GP*CP*GP*(PSU)P*AP*GP*UP*AP*GP*C)-3'), RNA (5'-R(*CP*GP*CP*UP*AP*CP*UP*AP*AP*CP*GP*CP*G)-3'), SULFATE ION
Authors:Lin, Y., Kielkopf, C.L.
Deposit date:2008-03-06
Release date:2008-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.
Biochemistry, 47, 2008
3CGR
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X-RAY STRUCTURE CONTAINING THE PSEUDOURIDYLATED U2 SNRNA AND INTRON BRANCH SITE CONSENSUS SEQUENCES
Descriptor:RNA (5'-R(*GP*CP*GP*CP*GP*GP*(PSU)P*AP*GP*UP*GP*C)-3'), RNA (5'-R(*CP*GP*CP*AP*CP*UP*AP*AP*CP*CP*GP*CP*G)-3'), SULFATE ION
Authors:Lin, Y., Kielkopf, C.L.
Deposit date:2008-03-06
Release date:2008-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.
Biochemistry, 47, 2008
3CGS
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X-RAY STRUCTURE CONTAINING THE PSEUDOURIDYLATED U2 SNRNA AND MAMMALIAN INTRON BRANCH SITE CONSENSUS SEQUENCES
Descriptor:RNA (5'-R(*GP*CP*GP*CP*GP*(PSU)P*AP*GP*UP*AP*GP*C)-3'), RNA (5'-R(*CP*GP*CP*UP*AP*CP*UP*GP*AP*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Lin, Y., Kielkopf, C.L.
Deposit date:2008-03-06
Release date:2008-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.
Biochemistry, 47, 2008
3IKT
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CRYSTAL STRUCTURE OF A REX-FAMILY REPRESSOR/DNA/NAD+ COMPLEX FROM THERMUS AQUATICUS
Descriptor:Redox-sensing transcriptional repressor rex, Rex operator DNA, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:McLaughlin, K.J., Kielkopf, C.L.
Deposit date:2009-08-06
Release date:2010-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural basis for NADH/NAD+ redox sensing by a Rex family repressor.
Mol.Cell, 38, 2010
3IKV
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CRYSTAL STRUCTURE OF A REX-FAMILY REPRESSOR R90D MUTANT FROM THERMUS AQUATICUS
Descriptor:Redox-sensing transcriptional repressor rex, CALCIUM ION
Authors:McLaughlin, K.J., Kielkopf, C.L.
Deposit date:2009-08-06
Release date:2010-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for NADH/NAD+ redox sensing by a Rex family repressor.
Mol.Cell, 38, 2010
3IL2
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CRYSTAL STRUCTURE OF A REX-FAMILY REPRESSOR R90D MUTANT/DNA COMPLEX FROM THERMUS AQUATICUS
Descriptor:Redox-sensing transcriptional repressor rex, Rex operator DNA
Authors:McLaughlin, K.J., Kielkopf, C.L.
Deposit date:2009-08-06
Release date:2010-06-09
Last modified:2012-02-01
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis for NADH/NAD+ redox sensing by a Rex family repressor.
Mol.Cell, 38, 2010
3VAF
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STRUCTURE OF U2AF65 VARIANT WITH BRU3 DNA
Descriptor:Splicing factor U2AF 65 kDa subunit, DNA 5'-D(*UP*UP*(BRU)P*(BRU)P*UP*UP*U)-3', 1,4-DIETHYLENE DIOXIDE, ...
Authors:Jenkins, J.L., Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
3VAG
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STRUCTURE OF U2AF65 VARIANT WITH BRU3C2 DNA
Descriptor:Splicing factor U2AF 65 kDa subunit, DNA 5'-D(*U*CP*(BRU)P*UP*UP*UP*U)-3', 1,4-DIETHYLENE DIOXIDE, ...
Authors:Jenkins, J.L., Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
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