1CVX
CRYSTAL STRUCTURE OF POLYAMIDE DIMER (IMPYHPPYBETADP)2 BOUND TO B-DNA DECAMER CCAGATCTGG
Summary for 1CVX
Entry DOI | 10.2210/pdb1cvx/pdb |
Descriptor | 5'-D(*CP*CP*AP*GP*AP*TP*CP*TP*GP*G)-3', HYDROXYPYRROLE-IMIDAZOLE-PYRROLE POLYAMIDE (3 entities in total) |
Functional Keywords | polyamide, minor groove recognition, ta recognition, double drug in minor groove, dna |
Total number of polymer chains | 2 |
Total formula weight | 7417.46 |
Authors | Kielkopf, C.L.,Bremer, R.E.,White, S.,Baird, E.E.,Dervan, P.B.,Rees, D.C. (deposition date: 1999-08-24, release date: 2000-01-15, Last modification date: 2024-02-07) |
Primary citation | Kielkopf, C.L.,Bremer, R.E.,White, S.,Szewczyk, J.W.,Turner, J.M.,Baird, E.E.,Dervan, P.B.,Rees, D.C. Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove. J.Mol.Biol., 295:557-567, 2000 Cited by PubMed: 10623546DOI: 10.1006/jmbi.1999.3364 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
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