1KPM | | FIRST STRUCTURAL EVIDENCE OF A SPECIFIC INHIBITION OF PHOSPHOLIPASE A2 BY VITAMIN E AND ITS IMPLICATIONS IN INFLAMMATION: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND VITAMIN E AT 1.8 A RESOLUTION. | | Descriptor: | Phospholipase A2, VITAMIN E, ACETIC ACID | | Authors: | Chandra, V., Jasti, J., Kaur, P., Betzel, C., Srinivasan, A., Singh, T.P. | | Deposit date: | 2002-01-01 | | Release date: | 2002-07-10 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | First Structural Evidence of a Specific Inhibition of Phospholipase A2 by alpha-Tocopherol (Vitamin E) and its
Implications in Inflammation: Crystal Structure of the Complex Formed Between Phospholipase A2 and
alpha-Tocopherol at 1.8 A Resolution
J.Mol.Biol., 320, 2002
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1JQ9 | | CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 FROM DABOIA RUSSELLI PULCHELLA AND A DESIGNED PENTAPEPTIDE PHE-LEU-SER-TYR-LYS AT 1.8 RESOLUTION | | Descriptor: | Phospholipase A2, Peptide inhibitor, ACETIC ACID | | Authors: | Chandra, V., Jasti, J., Kaur, P., Dey, S., Betzel, C., Singh, T.P. | | Deposit date: | 2001-08-04 | | Release date: | 2002-11-06 | | Last modified: | 2019-10-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of a Complex Formed between a Snake Venom Phospholipase A2 and a Potent Peptide Inhibitor Phe-Leu-Ser-Tyr-Lys at 1.8 A Resolution
J.BIOL.CHEM., 277, 2002
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1JQ8 | | DESIGN OF SPECIFIC INHIBITORS OF PHOSPHOLIPASE A2: CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 FROM DABOIA RUSSELLI PULCHELLA AND A DESIGNED PENTAPEPTIDE LEU-ALA-ILE-TYR-SER AT 2.0 RESOLUTION | | Descriptor: | Phospholipase A2, Peptide inhibitor, SULFATE ION, ... | | Authors: | Chandra, V., Jasti, J., Kaur, P., Dey, S., Betzel, C., Singh, T.P. | | Deposit date: | 2001-08-04 | | Release date: | 2002-11-06 | | Last modified: | 2019-10-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Design of specific peptide inhibitors of phospholipase A2: structure of a complex formed between Russell's viper phospholipase A2 and a designed peptide Leu-Ala-Ile-Tyr-Ser (LAIYS).
ACTA CRYSTALLOGR.,SECT.D, 58, 2002
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3CG9 | | CRYSTAL STRUCTURE OF THE COMPLEX OF PEPTIDOGLYCAN RECOGNITION PROTEIN WITH METHYLOXANE-2,3,4,5-TETROL AT 2.9 A RESOLUTION | | Descriptor: | Peptidoglycan recognition protein, alpha-L-rhamnopyranose, L(+)-TARTARIC ACID | | Authors: | Sharma, P., Kaur, A., Singh, N., Sharma, S., Bhushan, A., Pathak, K.M.L., Kaur, P., Singh, T.P. | | Deposit date: | 2008-03-05 | | Release date: | 2008-04-01 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of the complex of peptidoglycan recognition protein with methyoxane-2,3,4,5-tetrol at 2.9 A resolution
To be Published
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5ZTJ | | CRYSTAL STRUCTURE OF GYRASEA C-TERMINAL DOMAIN FROM SALMONELLA TYPHI AT 2.4A RESOLUTION | | Descriptor: | DNA gyrase subunit A | | Authors: | Sachdeva, E., Gupta, D., Tiwari, P., Kaur, G., Sharma, S., Singh, T.P., Ethayathulla, A.S., Kaur, P. | | Deposit date: | 2018-05-03 | | Release date: | 2019-05-15 | | Last modified: | 2020-05-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The pivot point arginines identified in the beta-pinwheel structure of C-terminal domain from Salmonella Typhi DNA Gyrase A subunit.
Sci Rep, 10, 2020
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6J90 | | CRYSTAL STRUCTURE OF GYRASEB N-TERMINAL DOMAIN COMPLEX WITH ATP FROM SALMONELLA TYPHI AT 2.2A RESOLUTION | | Descriptor: | DNA gyrase subunit B, CHLORIDE ION, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Kaur, G., Sachdeva, E., Tiwari, P., Gupta, D., Ethayathulla, A.S., Kaur, P. | | Deposit date: | 2019-01-21 | | Release date: | 2020-01-22 | | Last modified: | 2020-01-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of GyraseB N-Terminal Domain complex with ATP from Salmonella Typhi at 2.2A Resolution
To Be Published
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1MF4 | | STRUCTURE-BASED DESIGN OF POTENT AND SELECTIVE INHIBITORS OF PHOSPHOLIPASE A2: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSHOLIPASE A2 FROM NAJA NAJA SAGITTIFERA AND A DESIGNED PEPTIDE INHIBITOR AT 1.9 A RESOLUTION | | Descriptor: | Phospholipase A2, VAL-ALA-PHE-ARG-SER, CALCIUM ION | | Authors: | Singh, R.K., Vikram, P., Paramsivam, M., Jabeen, T., Sharma, S., Makker, J., Dey, S., Kaur, P., Srinivasan, A., Singh, T.P. | | Deposit date: | 2002-08-09 | | Release date: | 2003-09-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Design of specific peptide inhibitors for group I phospholipase A2: structure of a complex formed between phospholipase A2 from Naja naja sagittifera (group I) and a designed peptide inhibitor Val-Ala-Phe-Arg-Ser (VAFRS) at 1.9 A resolution reveals unique features
Biochemistry, 42, 2003
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2RD4 | | DESIGN OF SPECIFIC INHIBITORS OF PHOSPHOLIPASE A2: CRYSTAL STRUCTURE OF THE COMPLEX OF PHOSPHOLIPASE A2 WITH PENTAPEPTIDE LEU-VAL-PHE-PHE-ALA AT 2.9 A RESOLUTION | | Descriptor: | Phospholipase A2 isoform 1, Phospholipase A2 isoform 2, pentapeptide inhibitor, ... | | Authors: | Mirza, Z., Kaur, A., Singh, N., Sinha, M., Sharma, S., Srinivasan, A., Kaur, P., Singh, T.P. | | Deposit date: | 2007-09-21 | | Release date: | 2007-10-09 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.97 Å) | | Cite: | Design of specific inhibitors of Phospholipase A2: Crystal structure of the complex of phospholipase A2 with pentapeptide Leu-Val-Phe-Phe-Ala at 2.9 A resolution
To be Published
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3CR9 | | CRYSTAL STRUCTURE OF THE COMPLEX OF LACTOFERRIN WITH 6-(HYDROXYMETHYL)OXANE-2,3,4,5-TETROL AT 3.49 A RESOLUTION | | Descriptor: | Lactotransferrin, alpha-D-glucopyranose, FE (III) ION | | Authors: | Mir, R., Kaur, A., Singh, A.K., Singh, N., Kaur, P., Sharma, S., Singh, T.P. | | Deposit date: | 2008-04-05 | | Release date: | 2008-04-29 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.49 Å) | | Cite: | Crystal structure of the complex of Lactoferrin with 6-(Hydroxymethyl)oxane-2,3,4,5-tetrol at 3.49 A resolution
To be Published
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3PUD | | CRYSTAL STRUCTURE OF DHYDRODIPICOLINATE SYNTHASE FROM ACINETOBACTER BAUMANNII AT 2.8A RESOLUTION | | Descriptor: | Dihydrodipicolinate synthase, SULFATE ION, GLYCEROL | | Authors: | Jithesh, O., Yamini, S., Kaur, N., Gautam, A., Tewari, R., Kushwaha, G.S., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P. | | Deposit date: | 2010-12-04 | | Release date: | 2010-12-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of Dhydrodipicolinate synthase from Acinetobacter baumannii at 2.8A resolution
To be Published
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3PUE | | CRYSTAL STRUCTURE OF THE COMPLEX OF DHYDRODIPICOLINATE SYNTHASE FROM ACINETOBACTER BAUMANNII WITH LYSINE AT 2.6A RESOLUTION | | Descriptor: | Dihydrodipicolinate synthase, SULFATE ION, LYSINE, ... | | Authors: | Jithesh, O., Yamini, S., Kaur, N., Gautam, A., Tewari, R., Kushwaha, G.S., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P. | | Deposit date: | 2010-12-04 | | Release date: | 2010-12-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of the complex of Dhydrodipicolinate synthase from Acinetobacter baumannii with lysine at 2.6A resolution
To be Published
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3PUL | | CRYSTAL STRUCTURE OF THE COMPLEX OF DHYDRODIPICOLINATE SYNTHASE FROM ACINETOBACTER BAUMANNII WITH LYSINE AT 2.3A RESOLUTION | | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, SULFATE ION, ... | | Authors: | Jithesh, O., Yamini, S., Kaur, N., Gautam, A., Tewari, R., Kushwaha, G.S., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P. | | Deposit date: | 2010-12-06 | | Release date: | 2010-12-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the complex of Dhydrodipicolinate synthase from Acinetobacter baumannii with lysine at 2.3A resolution
to be published
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3S8H | | STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE COMPLEXED WITH 3-HYDROXYPROPANOIC ACID(HPA)AT 2.70 A RESOLUTION | | Descriptor: | Dihydrodipicolinate synthase, 3-HYDROXY-PROPANOIC ACID | | Authors: | Kumar, M., Kaur, N., Kumar, S., Sinha, M., Kaur, P., Sharma, S., Singh, T.P. | | Deposit date: | 2011-05-28 | | Release date: | 2011-06-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of dihydrodipicolinate synthase complexed with 3-Hydroxypropanoic acid(HPA)at 2.70 A resolution
TO BE PUBLISHED
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1FV0 | | FIRST STRUCTURAL EVIDENCE OF THE INHIBITION OF PHOSPHOLIPASE A2 BY ARISTOLOCHIC ACID: CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND ARISTOLOCHIC ACID | | Descriptor: | PHOSPHOLIPASE A2, SULFATE ION, ACETATE ION, ... | | Authors: | Chandra, V., Jasti, J., Kaur, P., Srinivasan, A., Betzel, C., Singh, T.P. | | Deposit date: | 2000-09-18 | | Release date: | 2002-08-28 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Basis of Phospholipase A2 Inhibition for the Synthesis of Prostaglandins by the Plant Alkaloid Aristolochic Acid from a 1.7 A Crystal Structure
Biochemistry, 41, 2002
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1OXL | | INHIBITION OF PHOSPHOLIPASE A2 (PLA2) BY (2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)-ACETIC ACID (INDOLE): CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PLA2 FROM RUSSELL'S VIPER AND INDOLE AT 1.8 RESOLUTION | | Descriptor: | Phospholipase A2 VRV-PL-VIIIa, (2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID, CARBONATE ION, ... | | Authors: | Chandra, V., Balasubramanya, R., Kaur, P., Singh, T.P. | | Deposit date: | 2003-04-02 | | Release date: | 2004-04-06 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the complex of the secretory phospholipase A2 from Daboia russelli pulchella with an endogenic indole derivative, 2-carbamoylmethyl-5-propyl-octahydro-indol-7-yl-acetic acid at 1.8 A resolution.
Biochim.Biophys.Acta, 1752, 2005
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1LN8 | | CRYSTAL STRUCTURE OF A NEW ISOFORM OF PHOSPHOLIPASE A2 FROM NAJA NAJA SAGITTIFERA AT 1.6 A RESOLUTION | | Descriptor: | Phospholipase A2, CALCIUM ION, PHOSPHATE ION | | Authors: | Singh, R.K., Vikram, P., Paramasivam, M., Jabeen, T., Sharma, S., Kaur, P., Srinivasan, A., Singh, T.P. | | Deposit date: | 2002-05-03 | | Release date: | 2003-05-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal Structure of a New Form of Phospholipase A2 from Naja naja sagittifera at 1.6 A Resolution
to be published
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1FB2 | | STRUCTURE OF PHOSPHOLIPASE A2 FROM DABOIA RUSSELLI PULCHELLA AT 1.95 | | Descriptor: | PHOSPHOLIPASE A2 | | Authors: | Chandra, V., Kaur, P., Betzel, C., Singh, T.P. | | Deposit date: | 2000-07-14 | | Release date: | 2001-07-25 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Regulation of catalytic function by molecular association: structure of phospholipase A2 from Daboia russelli pulchella (DPLA2) at 1.9 A resolution.
Acta Crystallogr.,Sect.D, 57, 2001
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1S6B | | X-RAY CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN TWO HOMOLOGOUS ISOFORMS OF PHOSPHOLIPASE A2 FROM NAJA NAJA SAGITTIFERA: PRINCIPLE OF MOLECULAR ASSOCIATION AND INACTIVATION | | Descriptor: | Phospholipase A2 isoform 1, Phospholipase A2 isoform 2, CALCIUM ION, ... | | Authors: | Jabeen, T., Sharma, S., Singh, R.K., Kaur, P., Singh, T.P. | | Deposit date: | 2004-01-23 | | Release date: | 2004-02-10 | | Last modified: | 2018-02-07 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of a calcium-induced dimer of two isoforms of cobra phospholipase A2 at 1.6 A resolution.
Proteins, 59, 2005
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1SZ8 | | CRYSTAL STRUCTURE OF AN ACIDIC PHOSPHOLIPASE A2 FROM NAJA NAJA SAGITTIFERA AT 1.5 A RESOLUTION | | Descriptor: | Phospholipase A2 isoform 3, CALCIUM ION, PHOSPHATE ION, ... | | Authors: | Singh, R.K., Sharma, S., Jabeen, T., Kaur, P., Singh, T.P. | | Deposit date: | 2004-04-05 | | Release date: | 2004-04-20 | | Last modified: | 2018-02-07 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structure of an Acidic Phospholipase A2 from Naja Naja Sagittifera at 1.5 A Resolution
To be Published
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5YL5 | | CRYSTAL STRUCTURE OF DODECAMERIC DEHYDROQUINATE DEHYDRATASE FROM ACINETOBACTER BAUMANNII AT 1.9A RESOLUTION | | Descriptor: | 3-dehydroquinate dehydratase, SULFATE ION, GLYCEROL, ... | | Authors: | Iqbal, N., Kaur, P., Sharma, S., Singh, T.P. | | Deposit date: | 2017-10-17 | | Release date: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of dodecameric Dehydroquinate dehydratase from Acinetobacter baumannii at 1.9A resolution
To Be Published
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1IC6 | | STRUCTURE OF A SERINE PROTEASE PROTEINASE K FROM TRITIRACHIUM ALBUM LIMBER AT 0.98 A RESOLUTION | | Descriptor: | PROTEINASE K, CALCIUM ION, NITRATE ION | | Authors: | Betzel, C., Gourinath, S., Kumar, P., Kaur, P., Perbandt, M., Eschenburg, S., Singh, T.P. | | Deposit date: | 2001-03-30 | | Release date: | 2001-04-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (0.98 Å) | | Cite: | Structure of a serine protease proteinase K from Tritirachium album limber at 0.98 A resolution.
Biochemistry, 40, 2001
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1LJY | | CRYSTAL STRUCTURE OF A NOVEL REGULATORY 40 KDA MAMMARY GLAND PROTEIN (MGP-40) SECRETED DURING INVOLUTION | | Descriptor: | MGP-40, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Mohanty, A.K., Singh, G., Paramasivam, M., Saravanan, K., Jabeen, T., Sharma, S., Yadav, S., Kaur, P., Kumar, P., Srinivasan, A., Singh, T.P. | | Deposit date: | 2002-04-23 | | Release date: | 2003-03-18 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal Structure of a Novel Regulatory 40 kDa Mammary Gland Protein (MGP-40) secreted during Involution
J.Biol.Chem., 278, 2003
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1SQY | | STRUCTURE OF HUMAN DIFERRIC LACTOFERRIN AT 2.5A RESOLUTION USING CRYSTALS GROWN AT PH 6.5 | | Descriptor: | lactoferrin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FE (III) ION, ... | | Authors: | Vikram, P., Prem Kumar, R., Singh, N., Kumar, J., Ethayathulla, A.S., Sharma, S., Kaur, P., Singh, T.P. | | Deposit date: | 2004-03-22 | | Release date: | 2004-04-13 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of human diferric lactoferrin at 2.5A resolution using crystals grown at pH 6.5.
To be Published
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2DP5 | | STRUCTURE OF STREPTOCOCCUS PYOGENES BACTERIOPHAGE-ASSOCIATED HYALURONATE LYASE HYLP2 | | Descriptor: | Hyaluronidase | | Authors: | Mishra, P., Bhakuni, V., Prem Kumar, R., Singh, N., Sharma, S., Kaur, P., Singh, T.P. | | Deposit date: | 2006-05-06 | | Release date: | 2006-05-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.55 Å) | | Cite: | Structure of streptococcus pyogenes bacteriophage-associated hyaluronate lyase Hylp2
To be Published
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2O92 | | CRYSTAL STRUCTURE OF A SIGNALLING PROTEIN (SPG-40) COMPLEX WITH TETRASACCHARIDE AT 3.0A RESOLUTION | | Descriptor: | Chitinase-3-like protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Sharma, P., Singh, N., Sharma, S., Kaur, P., Singh, T.P. | | Deposit date: | 2006-12-13 | | Release date: | 2006-12-26 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of a signalling protein (SPG-40) complex with tetrasaccharide at 3.0A resolution
To be Published
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