6CS9
| Crystal structure of human beta-defensin 2 in complex with PIP2 | Descriptor: | Beta-defensin 4A, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | Authors: | Jarva, M, Phan, K, Lay, F.T, Humble, C, Hulett, M, Kvansakul, M. | Deposit date: | 2018-03-20 | Release date: | 2018-07-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Human beta-defensin 2 killsCandida albicansthrough phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization. Sci Adv, 4, 2018
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5VYP
| Crystal structure of the Plant Defensin NsD7 bound to PIP2 | Descriptor: | Defensin NsD7, GLYCEROL, SULFATE ION, ... | Authors: | Jarva, M, Lay, F.T, Hulett, M, Kvansakul, M. | Deposit date: | 2017-05-25 | Release date: | 2017-08-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the defensin NsD7 in complex with PIP2 reveals that defensin : lipid oligomer topologies are dependent on lipid type. FEBS Lett., 591, 2017
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6B55
| Crystal structure of the Plant Defensin NaD1 complexed with phosphatidic acid | Descriptor: | 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, 1,2-ETHANEDIOL, Flower-specific defensin, ... | Authors: | Jarva, M, Phan, K, Humble, C, Lay, F.T, Hulett, M, Kvansakul, M. | Deposit date: | 2017-09-28 | Release date: | 2018-05-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex. Nat Commun, 9, 2018
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8BEG
| Structure of Ig-like domains from PrgB | Descriptor: | MAGNESIUM ION, PrgB | Authors: | Jarva, M, Schmitt, A, Berntsson, R.P.-A. | Deposit date: | 2022-10-21 | Release date: | 2022-11-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structural foundation for the role of enterococcal PrgB in conjugation, biofilm formation, and virulence. Elife, 12, 2023
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6FMD
| Targeting myeloid differentiation using potent human dihydroorotate dehydrogenase (hDHODH) inhibitors based on 2-hydroxypyrazolo[1,5-a]pyridine scaffold | Descriptor: | 2-oxidanyl-~{N}-[2,3,5,6-tetrakis(fluoranyl)-4-phenyl-phenyl]pyrazolo[1,5-a]pyridine-3-carboxamide, ACETATE ION, CHLORIDE ION, ... | Authors: | Goyal, P, Jarva, M, Andersson, M, Lolli, M.L, Friemann, R. | Deposit date: | 2018-01-30 | Release date: | 2018-07-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors. J. Med. Chem., 61, 2018
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4JC6
| Mercury activation of the plant aquaporin SoPIP2;1 - structural and functional characterization | Descriptor: | Aquaporin, CADMIUM ION, MERCURY (II) ION, ... | Authors: | Frick, A, Jarva, M, Nyblom, M, Ekvall, M, Uzdavinys, P, Tornroth-Horsefield, S. | Deposit date: | 2013-02-21 | Release date: | 2013-09-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.152 Å) | Cite: | Mercury increases water permeability of a plant aquaporin through a non-cysteine-related mechanism. Biochem.J., 454, 2013
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4IA4
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6FBX
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6H1N
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