Crystal structure of the Plant Defensin NsD7 bound to PIP2

Summary for 5VYP

DescriptorDefensin NsD7, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, SULFATE ION, ... (5 entities in total)
Functional Keywordsantimicrobial, antifungal, defensin, antimicrobial protein
Biological sourceNicotiana suaveolens (Australian tobacco)
Cellular locationVacuole  C0HK49
Total number of polymer chains24
Total molecular weight151086.12
Jarva, M.,Lay, F.T.,Hulett, M.,Kvansakul, M. (deposition date: 2017-05-25, release date: 2017-08-02, Last modification date: 2017-09-27)
Primary citation
Jarva, M.,Lay, F.T.,Hulett, M.D.,Kvansakul, M.
Structure of the defensin NsD7 in complex with PIP2 reveals that defensin : lipid oligomer topologies are dependent on lipid type.
FEBS Lett., 591:2482-2490, 2017
PubMed: 28741756 (PDB entries with the same primary citation)
DOI: 10.1002/1873-3468.12761
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27170.5%0.3%4.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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