Author results

4GFX
  • Download 4gfx
  • View 4gfx
Molmil generated image of 4gfx
CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF TXNIP
Descriptor:Thioredoxin-interacting protein, GLYCEROL
Authors:Hwang, J., Kim, M.H.
Deposit date:2012-08-04
Release date:2014-02-05
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein.
Nat Commun, 5, 2014
4LL1
  • Download 4ll1
  • View 4ll1
Molmil generated image of 4ll1
THE STRUCTURE OF THE TRX AND TXNIP COMPLEX
Descriptor:Thioredoxin-interacting protein, Thioredoxin
Authors:Hwang, J., Kim, M.H.
Deposit date:2013-07-09
Release date:2014-02-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
Nat Commun, 5, 2014
4LL4
  • Download 4ll4
  • View 4ll4
Molmil generated image of 4ll4
THE STRUCTURE OF THE TRX AND TXNIP COMPLEX
Descriptor:Thioredoxin-interacting protein, Thioredoxin
Authors:Hwang, J., Kim, M.H.
Deposit date:2013-07-09
Release date:2014-02-05
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
Nat Commun, 5, 2014
2XMQ
  • Download 2xmq
  • View 2xmq
Molmil generated image of 2xmq
CRYSTAL STRUCTURE OF HUMAN NDRG2 PROTEIN PROVIDES INSIGHT INTO ITS ROLE AS A TUMOR SUPPRESSOR
Descriptor:PROTEIN NDRG2, ACETATE ION
Authors:Hwang, J., Kim, Y., Lee, H., Kim, M.H.
Deposit date:2010-07-29
Release date:2011-01-19
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor.
J.Biol.Chem., 286, 2011
2XMR
  • Download 2xmr
  • View 2xmr
Molmil generated image of 2xmr
CRYSTAL STRUCTURE OF HUMAN NDRG2 PROTEIN PROVIDES INSIGHT INTO ITS ROLE AS A TUMOR SUPPRESSOR
Descriptor:PROTEIN NDRG2, CALCIUM ION, ACETATE ION, ...
Authors:Hwang, J., Kim, Y., Lee, H., Kim, M.H.
Deposit date:2010-07-29
Release date:2011-01-19
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor.
J.Biol.Chem., 286, 2011
2XMS
  • Download 2xms
  • View 2xms
Molmil generated image of 2xms
CRYSTAL STRUCTURE OF HUMAN NDRG2 PROTEIN PROVIDES INSIGHT INTO ITS ROLE AS A TUMOR SUPPRESSOR
Descriptor:PROTEIN NDRG2, CHLORIDE ION, IMIDAZOLE
Authors:Hwang, J., Kim, Y., Lee, H., Kim, M.H.
Deposit date:2010-07-29
Release date:2011-01-19
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor.
J.Biol.Chem., 286, 2011
4IVN
  • Download 4ivn
  • View 4ivn
Molmil generated image of 4ivn
THE VIBRIO VULNIFICUS NANR PROTEIN COMPLEXED WITH MANNAC-6P
Descriptor:Transcriptional regulator, 2-(ACETYLAMINO)-2-DEOXY-6-O-PHOSPHONO-ALPHA-D-MANNOPYRANOSE
Authors:Hwang, J., Kim, M.H.
Deposit date:2013-01-23
Release date:2013-07-17
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the regulation of sialic acid catabolism by the Vibrio vulnificus transcriptional repressor NanR
Proc.Natl.Acad.Sci.USA, 110, 2013
5DQY
  • Download 5dqy
  • View 5dqy
Molmil generated image of 5dqy
A FULLY OXIDIZED HUMAN THIOREDOXIN
Descriptor:Thioredoxin, BENZOIC ACID, CHLORIDE ION, ...
Authors:Hwang, J.
Deposit date:2015-09-15
Release date:2015-12-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of fully oxidized human thioredoxin.
Biochem.Biophys.Res.Commun., 467, 2015
5HWT
  • Download 5hwt
  • View 5hwt
Molmil generated image of 5hwt
CRYSTAL STRUCTURE OF APO-PAS1
Descriptor:Sensor histidine kinase TodS
Authors:Hwang, J., Koh, S.
Deposit date:2016-01-29
Release date:2016-03-02
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Insights into Toluene Sensing in the TodS/TodT Signal Transduction System.
J. Biol. Chem., 291, 2016
5HWV
  • Download 5hwv
  • View 5hwv
Molmil generated image of 5hwv
CRYSTAL STRUCTURE OF PAS1 COMPLEXED WITH TOLUENE
Descriptor:Sensor histidine kinase TodS, TOLUENE
Authors:Hwang, J., Koh, S.
Deposit date:2016-01-29
Release date:2016-03-02
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Molecular Insights into Toluene Sensing in the TodS/TodT Signal Transduction System.
J. Biol. Chem., 291, 2016
5HWW
  • Download 5hww
  • View 5hww
Molmil generated image of 5hww
CRYSTAL STRUCTURE OF PAS1 COMPLEXED WITH 1,2,4-TMB
Descriptor:Sensor histidine kinase TodS, 1,2,4-trimethylbenzene
Authors:Hwang, J., Koh, S.
Deposit date:2016-01-29
Release date:2016-03-02
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Insights into Toluene Sensing in the TodS/TodT Signal Transduction System.
J. Biol. Chem., 291, 2016
5XLN
  • Download 5xln
  • View 5xln
Molmil generated image of 5xln
CRYSTAL STRUCTURE OF THE TRS_UNE-T AND 4EHP COMPLEX
Descriptor:Eukaryotic translation initiation factor 4E type 2, Threonine--tRNA ligase, cytoplasmic
Authors:Hwang, J., Nguyen, L.T., Kim, M.H.
Deposit date:2017-05-11
Release date:2018-11-21
Last modified:2019-06-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A threonyl-tRNA synthetase-mediated translation initiation machinery.
Nat Commun, 10, 2019
2XXN
  • Download 2xxn
  • View 2xxn
Molmil generated image of 2xxn
STRUCTURE OF THE VIRF4-HAUSP TRAF DOMAIN COMPLEX
Descriptor:UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7, K10
Authors:Choi, W.C., Hwang, J., Kim, M.H.
Deposit date:2010-11-11
Release date:2011-11-09
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Bilateral Inhibition of Hausp Deubiquitinase by a Viral Interferon Regulatory Factor Protein
Nat.Struct.Mol.Biol., 18, 2011
1MKY
  • Download 1mky
  • View 1mky
Molmil generated image of 1mky
STRUCTURAL ANALYSIS OF THE DOMAIN INTERACTIONS IN DER, A SWITCH PROTEIN CONTAINING TWO GTPASE DOMAINS
Descriptor:Probable GTP-binding protein engA, PHOSPHATE ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Robinson, V.L., Hwang, J., Fox, E., Inouye, M., Stock, A.M.
Deposit date:2002-08-29
Release date:2003-01-14
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Domain Arrangement of Der, a Switch Protein Containing Two GTPase Domains
Structure, 10, 2002
2PH7
  • Download 2ph7
  • View 2ph7
Molmil generated image of 2ph7
CRYSTAL STRUCTURE OF AF2093 FROM ARCHAEOGLOBUS FULGIDUS
Descriptor:Uncharacterized protein AF_2093
Authors:Chang, J.C., Yang, H., Hwang, J., Zhu, J., Chen, L., Fu, Z.-Q., Xu, H., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2007-04-10
Release date:2007-05-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of AF2093 from Archaeoglobus fulgidus.
To be Published
6A7H
  • Download 6a7h
  • View 6a7h
Molmil generated image of 6a7h
BACTERIAL PROTEIN TOXINS
Descriptor:RTX toxin, SULFATE ION
Authors:Kim, M.H., Hwang, J., Jang, S.Y.
Deposit date:2018-07-03
Release date:2018-10-10
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structural basis of inactivation of Ras and Rap1 small GTPases by Ras/Rap1-specific endopeptidase from the sepsis-causing pathogenVibrio vulnificus
J. Biol. Chem., 293, 2018
6A8J
  • Download 6a8j
  • View 6a8j
Molmil generated image of 6a8j
CRYSTAL STRUCTURE OF BACTERIAL PROTEIN TOXINS
Descriptor:RTX toxin, SULFATE ION, GLYCEROL
Authors:Kim, M.H., Hwang, J., Jang, S.Y.
Deposit date:2018-07-09
Release date:2018-10-10
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.711 Å)
Cite:Structural basis of inactivation of Ras and Rap1 small GTPases by Ras/Rap1-specific endopeptidase from the sepsis-causing pathogenVibrio vulnificus
J. Biol. Chem., 293, 2018
3I0O
  • Download 3i0o
  • View 3i0o
Molmil generated image of 3i0o
CRYSTAL STRUCTURE OF SPECTINOMYCIN PHOSPHOTRANSFERASE, APH(9)-IA, IN COMPLEX WITH ADP AND SPECTINOMCYIN
Descriptor:Spectinomycin phosphotransferase, ADENOSINE-5'-DIPHOSPHATE, SPECTINOMYCIN, ...
Authors:Fong, D.H., Lemke, C.T., Hwang, J., Xiong, B., Berghuis, A.M.
Deposit date:2009-06-25
Release date:2010-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the antibiotic resistance factor spectinomycin phosphotransferase from Legionella pneumophila.
J.Biol.Chem., 285, 2010
3I1A
  • Download 3i1a
  • View 3i1a
Molmil generated image of 3i1a
CRYSTAL STRUCTURE OF APO SPECTINOMYCIN PHOSPHOTRANSFERASE, APH(9)-IA
Descriptor:Spectinomycin phosphotransferase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ...
Authors:Berghuis, A.M., Fong, D.H., Lemke, C.T., Hwang, J., Xiong, B.
Deposit date:2009-06-25
Release date:2010-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the antibiotic resistance factor spectinomycin phosphotransferase from Legionella pneumophila.
J.Biol.Chem., 285, 2010
3KZ9
  • Download 3kz9
  • View 3kz9
Molmil generated image of 3kz9
CRYSTAL STRUCTURE OF THE MASTER TRANSCRIPTIONAL REGULATOR, SMCR, IN VIBRIO VULNIFICUS PROVIDES INSIGHT INTO ITS DNA RECOGNITION MECHANISM
Descriptor:SmcR, SULFATE ION
Authors:Kim, M.H., Kim, Y., Choi, W.-C., Hwang, J.
Deposit date:2009-12-08
Release date:2010-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of SmcR, a quorum-sensing master regulator of Vibrio vulnificus, provides insight into its regulation of transcription
J.Biol.Chem., 285, 2010
3Q2J
  • Download 3q2j
  • View 3q2j
Molmil generated image of 3q2j
CRYSTAL STRUCTURE OF 3',5"-AMINOGLYCOSIDE PHOSPHOTRANSFERASE TYPE IIIA PROTEIN KINASE INHIBITOR CKI-7 COMPLEX
Descriptor:Aminoglycoside 3'-phosphotransferase, CALCIUM ION, N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE
Authors:Fong, D.H., Xiong, B., Hwang, J., Berghuis, A.M.
Deposit date:2010-12-20
Release date:2011-05-18
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.1501 Å)
Cite:Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor.
Plos One, 6, 2011
3Q2M
  • Download 3q2m
  • View 3q2m
Molmil generated image of 3q2m
CRYSTAL STRUCTURE OF SPECTINOMYCIN PHOSPHOTRANSFERASE, APH(9)-IA, PROTEIN KINASE INHIBITOR CKI-7 COMPLEX
Descriptor:Spectinomycin phosphotransferase, N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE, NICKEL (II) ION
Authors:Berghuis, A.M., Fong, D.H., Xiong, B., Hwang, J.
Deposit date:2010-12-20
Release date:2011-05-18
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor.
Plos One, 6, 2011
5X3R
  • Download 5x3r
  • View 5x3r
Molmil generated image of 5x3r
CRYSTAL STRUCTURE OF THE SMCR COMPLEXED WITH QSTATIN
Descriptor:LuxR family transcriptional regulator, 1-(5-bromanylthiophen-2-yl)sulfonylpyrazole, SULFATE ION
Authors:Jang, S.Y., Hwang, J., Kim, M.H.
Deposit date:2017-02-07
Release date:2018-01-24
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:QStatin, a Selective Inhibitor of Quorum Sensing inVibrioSpecies
MBio, 9, 2018
2QMQ
  • Download 2qmq
  • View 2qmq
Molmil generated image of 2qmq
CRYSTAL STRUCTURE OF A N-MYC DOWNSTREAM REGULATED 2 PROTEIN (NDRG2, SYLD, NDR2, AI182517, AU040374) FROM MUS MUSCULUS AT 1.70 A RESOLUTION
Descriptor:Protein NDRG2, MAGNESIUM ION, BENZOIC ACID, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2007-07-16
Release date:2007-09-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor.
J.Biol.Chem., 286, 2011
6J10
  • Download 6j10
  • View 6j10
Molmil generated image of 6j10
CICLOPIROX INHIBITS HEPATITIS B VIRUS SECRETION BY BLOCKING CAPSID ASSEMBLY
Descriptor:Capsid protein, 6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one
Authors:Park, S., Jin, M.S., Cho, Y., Kang, J., Kim, S., Park, M., Park, H., Kim, J., Park, S., Hwang, J., Kim, Y., Kim, Y.J.
Deposit date:2018-12-27
Release date:2019-04-17
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly.
Nat Commun, 10, 2019
<12>