Author results

1MAE
  • Download 1mae
  • View 1mae
Molmil generated image of 1mae
THE ACTIVE SITE STRUCTURE OF METHYLAMINE DEHYDROGENASE: HYDRAZINES IDENTIFY C6 AS THE REACTIVE SITE OF THE TRYPTOPHAN DERIVED QUINONE COFACTOR
Descriptor:METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT), METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), NITROGEN MOLECULE
Authors:Huizinga, E.G., Vellieux, F.M.D., Hol, W.G.J.
Deposit date:1992-05-20
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor.
Biochemistry, 31, 1992
1MAF
  • Download 1maf
  • View 1maf
Molmil generated image of 1maf
THE ACTIVE SITE STRUCTURE OF METHYLAMINE DEHYDROGENASE: HYDRAZINES IDENTIFY C6 AS THE REACTIVE SITE OF THE TRYPTOPHAN DERIVED QUINONE COFACTOR
Descriptor:METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT), METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), NITROGEN MOLECULE
Authors:Huizinga, E.G., Vellieux, F.M.D., Hol, W.G.J.
Deposit date:1992-05-20
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor.
Biochemistry, 31, 1992
2MAD
  • Download 2mad
  • View 2mad
Molmil generated image of 2mad
THE ACTIVE SITE STRUCTURE OF METHYLAMINE DEHYDROGENASE: HYDRAZINES IDENTIFY C6 AS THE REACTIVE SITE OF THE TRYPTOPHAN DERIVED QUINONE COFACTOR
Descriptor:METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT), METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT)
Authors:Huizinga, E.G., Vellieux, F.M.D., Hol, W.G.J.
Deposit date:1992-05-20
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor.
Biochemistry, 31, 1992
1ATZ
  • Download 1atz
  • View 1atz
Molmil generated image of 1atz
HUMAN VON WILLEBRAND FACTOR A3 DOMAIN
Descriptor:VON WILLEBRAND FACTOR
Authors:Huizinga, E.G., Gros, P.
Deposit date:1997-08-15
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the A3 domain of human von Willebrand factor: implications for collagen binding.
Structure, 5, 1997
1I8N
  • Download 1i8n
  • View 1i8n
Molmil generated image of 1i8n
CRYSTAL STRUCTURE OF LEECH ANTI-PLATELET PROTEIN
Descriptor:ANTI-PLATELET PROTEIN, PROPIONAMIDE
Authors:Huizinga, E.G., Schouten, A., Connolly, T.M., Kroon, J., Sixma, J.J., Gros, P.
Deposit date:2001-03-15
Release date:2001-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of leech anti-platelet protein, an inhibitor of haemostasis.
Acta Crystallogr.,Sect.D, 57, 2001
1M0Z
  • Download 1m0z
  • View 1m0z
Molmil generated image of 1m0z
CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR BINDING DOMAIN OF GLYCOPROTEIN IB ALPHA
Descriptor:Glycoprotein Ib alpha
Authors:Huizinga, E.G., Tsuji, S., Romijn, R.A.P., Schiphorst, M.E., de Groot, P.G., Sixma, J.J., Gros, P.
Deposit date:2002-06-16
Release date:2002-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.
Science, 297, 2002
1M10
  • Download 1m10
  • View 1m10
Molmil generated image of 1m10
CRYSTAL STRUCTURE OF THE COMPLEX OF GLYCOPROTEIN IB ALPHA AND THE VON WILLEBRAND FACTOR A1 DOMAIN
Descriptor:von Willebrand Factor, Glycoprotein Ib alpha
Authors:Huizinga, E.G., Tsuji, S., Romijn, R.A.P., Schiphorst, M.E., de Groot, P.G., Sixma, J.J., Gros, P.
Deposit date:2002-06-16
Release date:2002-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.
Science, 297, 2002
6QFY
  • Download 6qfy
  • View 6qfy
Molmil generated image of 6qfy
CRYSTAL STRUCTURE OF PORCINE HEMAGGLUTINATING ENCEPHALOMYELITIS VIRUS SPIKE PROTEIN LECTIN DOMAIN
Descriptor:Spike glycoprotein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Huizinga, E.G., Bakkers, M., Lang, Y.
Deposit date:2019-01-10
Release date:2019-02-06
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
1FE8
  • Download 1fe8
  • View 1fe8
Molmil generated image of 1fe8
CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR A3 DOMAIN IN COMPLEX WITH A FAB FRAGMENT OF IGG RU5 THAT INHIBITS COLLAGEN BINDING
Descriptor:VON WILLEBRAND FACTOR, IMMUNOGLOBULIN IGG RU5, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Bouma, B., Huizinga, E.G., Schiphorst, M.E., Sixma, J.J., Kroon, J., Gros, P.
Deposit date:2000-07-21
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Identification of the collagen-binding site of the von Willebrand factor A3-domain.
J.Biol.Chem., 276, 2001
2A73
  • Download 2a73
  • View 2a73
Molmil generated image of 2a73
HUMAN COMPLEMENT COMPONENT C3
Descriptor:Complement C3, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Janssen, B.J.C., Huizinga, E.G., Raaijmakers, H.C.A., Roos, A., Daha, M.R., Nilsson-Ekdahl, K., Nilsson, B., Gros, P.
Deposit date:2005-07-04
Release date:2005-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437, 2005
2A74
  • Download 2a74
  • View 2a74
Molmil generated image of 2a74
HUMAN COMPLEMENT COMPONENT C3C
Descriptor:Complement Component C3c, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, GLYCEROL, ...
Authors:Janssen, B.J.C., Huizinga, E.G., Raaijmakers, H.C.A., Roos, A., Daha, M.R., Nilsson-Ekdahl, K., Nilsson, B., Gros, P.
Deposit date:2005-07-04
Release date:2005-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437, 2005
2ADF
  • Download 2adf
  • View 2adf
Molmil generated image of 2adf
CRYSTAL STRUCTURE AND PARATOPE DETERMINATION OF 82D6A3, AN ANTITHROMBOTIC ANTIBODY DIRECTED AGAINST THE VON WILLEBRAND FACTOR A3-DOMAIN
Descriptor:Von Willebrand factor, 82D6A3 IgG, ACETIC ACID, ...
Authors:Staelens, S., Hadders, M.A., Vauterin, S., Platteau, C., Vanhoorelbeke, K., Huizinga, E.G., Deckmyn, H.
Deposit date:2005-07-20
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Paratope determination of the antithrombotic antibody 82D6A3 based on the crystal structure of its complex with the von Willebrand factor A3-domain
J.Biol.Chem., 281, 2006
2I6Q
  • Download 2i6q
  • View 2i6q
Molmil generated image of 2i6q
COMPLEMENT COMPONENT C2A
Descriptor:Complement C2a fragment, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Milder, F.J., Raaijmakers, H.C.A., Vandeputte, D.A.A., Schouten, A., Huizinga, E.G., Romijn, R.A., Hemrika, W., Roos, A., Daha, M.R., Gros, P.
Deposit date:2006-08-29
Release date:2006-10-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of complement component c2a: implications for convertase formation and substrate binding.
Structure, 14, 2006
2I6S
  • Download 2i6s
  • View 2i6s
Molmil generated image of 2i6s
COMPLEMENT COMPONENT C2A
Descriptor:Complement C2a fragment, N-ACETYL-D-GLUCOSAMINE, BETA-L-FUCOSE, ...
Authors:Milder, F.J., Raaijmakers, H.C.A., Vandeputte, D.A.A., Schouten, A., Huizinga, E.G., Romijn, R.A., Hemrika, W., Roos, A., Daha, M.R., Gros, P.
Deposit date:2006-08-29
Release date:2006-10-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of complement component c2a: implications for convertase formation and substrate binding.
Structure, 14, 2006
2OK5
  • Download 2ok5
  • View 2ok5
Molmil generated image of 2ok5
HUMAN COMPLEMENT FACTOR B
Descriptor:Complement factor B, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Milder, F.J., Gomes, L., Schouten, A., Janssen, B.J.C., Huizinga, E.G., Romijn, R.A., Hemrika, W., Roos, A., Daha, M.R., Gros, P.
Deposit date:2007-01-16
Release date:2007-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Factor B structure provides insights into activation of the central protease of the complement system.
Nat.Struct.Mol.Biol., 14, 2007
3CL4
  • Download 3cl4
  • View 3cl4
Molmil generated image of 3cl4
CRYSTAL STRUCTURE OF BOVINE CORONAVIRUS HEMAGGLUTININ-ESTERASE
Descriptor:Hemagglutinin-esterase, N-ACETYL-D-GLUCOSAMINE, POTASSIUM ION
Authors:Zeng, Q.H., Langereis, M.A., van Vliet, A.L.W., Huizinga, E.G., de Groot, R.J.
Deposit date:2008-03-18
Release date:2008-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of coronavirus hemagglutinin-esterase offers insight into corona and influenza virus evolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3CL5
  • Download 3cl5
  • View 3cl5
Molmil generated image of 3cl5
STRUCTURE OF CORONAVIRUS HEMAGGLUTININ-ESTERASE IN COMPLEX WITH 4,9-O-DIACETYL SIALIC ACID
Descriptor:Hemagglutinin-esterase, N-ACETYL-D-GLUCOSAMINE, methyl 4,9-di-O-acetyl-5-(acetylamino)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acid, ...
Authors:Zeng, Q.H., Langereis, M.A., van Vliet, A.L.W., Huizinga, E.G., de Groot, R.J.
Deposit date:2008-03-18
Release date:2008-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of coronavirus hemagglutinin-esterase offers insight into corona and influenza virus evolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3D66
  • Download 3d66
  • View 3d66
Molmil generated image of 3d66
CRYSTAL STRUCTURE OF THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR (TAFI)
Descriptor:Carboxypeptidase B2, N-ACETYL-D-GLUCOSAMINE, ZINC ION
Authors:Brondijk, T.H.C., Huizinga, E.G.
Deposit date:2008-05-19
Release date:2008-07-01
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood, 112, 2008
3D67
  • Download 3d67
  • View 3d67
Molmil generated image of 3d67
CRYSTAL STRUCTURE OF THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR (TAFI) IN COMPLEX WITH 2-GUANIDINO-ETHYL-MERCAPTOSUCCINIC ACID (GEMSA)
Descriptor:Carboxypeptidase B2, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Brondijk, T.H.C., Huizinga, E.G.
Deposit date:2008-05-19
Release date:2008-07-01
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood, 112, 2008
3D68
  • Download 3d68
  • View 3d68
Molmil generated image of 3d68
CRYSTAL STRUCTURE OF A T325I/T329I/H333Y/H335Q MUTANT OF THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR (TAFI-IIYQ)
Descriptor:Carboxypeptidase B2, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Brondijk, T.H.C., Huizinga, E.G.
Deposit date:2008-05-19
Release date:2008-07-01
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood, 112, 2008
3I1K
  • Download 3i1k
  • View 3i1k
Molmil generated image of 3i1k
STRUCTURE OF PORCINE TOROVIRUS HEMAGGLUTININ-ESTERASE
Descriptor:Hemagglutinin-esterase protein, ACETIC ACID, N-ACETYL-D-GLUCOSAMINE
Authors:Zeng, Q.H., Huizinga, E.G.
Deposit date:2009-06-26
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for ligand and substrate recognition by torovirus hemagglutinin esterases
Proc.Natl.Acad.Sci.USA, 106, 2009
3I1L
  • Download 3i1l
  • View 3i1l
Molmil generated image of 3i1l
STRUCTURE OF PORCINE TOROVIRUS HEMAGGLUTININ-ESTERASE IN COMPLEX WITH ITS RECEPTOR
Descriptor:Hemagglutinin-esterase protein, methyl 4,9-di-O-acetyl-5-(acetylamino)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acid, ACETIC ACID, ...
Authors:Zeng, Q.H., Huizinga, E.G.
Deposit date:2009-06-26
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural basis for ligand and substrate recognition by torovirus hemagglutinin esterases
Proc.Natl.Acad.Sci.USA, 106, 2009
3I26
  • Download 3i26
  • View 3i26
Molmil generated image of 3i26
STRUCTURE OF BOVINE TOROVIRUS HEMAGGLUTININ-ESTERASE
Descriptor:Hemagglutinin-esterase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Zeng, Q.H., Huizinga, E.G.
Deposit date:2009-06-29
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for ligand and substrate recognition by torovirus hemagglutinin esterases
Proc.Natl.Acad.Sci.USA, 106, 2009
3I27
  • Download 3i27
  • View 3i27
Molmil generated image of 3i27
STRUCTURE OF BOVINE TOROVIRUS HEMAGGLUTININ-ESTERASE IN COMPLEX WITH RECEPTOR
Descriptor:Hemagglutinin-esterase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Zeng, Q.H., Huizinga, E.G.
Deposit date:2009-06-29
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for ligand and substrate recognition by torovirus hemagglutinin esterases
Proc.Natl.Acad.Sci.USA, 106, 2009
3KGR
  • Download 3kgr
  • View 3kgr
Molmil generated image of 3kgr
CRYSTAL STRUCTURE OF THE HUMAN LEUKOCYTE-ASSOCIATED IG-LIKE RECEPTOR-1 (LAIR-1)
Descriptor:Leukocyte-associated immunoglobulin-like receptor 1, GLYCINE, GLYCEROL
Authors:Brondijk, T.H.C., Huizinga, E.G., Ballering, J.
Deposit date:2009-10-29
Release date:2009-12-22
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI
Blood, 115, 2010
<12>