1FE8
CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR A3 DOMAIN IN COMPLEX WITH A FAB FRAGMENT OF IGG RU5 THAT INHIBITS COLLAGEN BINDING
Summary for 1FE8
Entry DOI | 10.2210/pdb1fe8/pdb |
Related | 1AO3 1ATZ |
Descriptor | VON WILLEBRAND FACTOR, IMMUNOGLOBULIN IGG RU5, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | collagen binding, conformational changes, epitope, von willebrand factor a-type domain, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 9 |
Total formula weight | 201594.32 |
Authors | Bouma, B.,Huizinga, E.G.,Schiphorst, M.E.,Sixma, J.J.,Kroon, J.,Gros, P. (deposition date: 2000-07-21, release date: 2001-04-04, Last modification date: 2020-07-29) |
Primary citation | Romijn, R.A.,Bouma, B.,Wuyster, W.,Gros, P.,Kroon, J.,Sixma, J.J.,Huizinga, E.G. Identification of the collagen-binding site of the von Willebrand factor A3-domain. J.Biol.Chem., 276:9985-9991, 2001 Cited by PubMed: 11098050DOI: 10.1074/jbc.M006548200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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