Author results

2JHB
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CORE BINDING FACTOR BETA
Descriptor:PROTEIN (CORE BINDING FACTOR BETA)
Authors:Huang, X., Peng, J., Speck, N.A., Bushweller, J.H.
Deposit date:1999-03-17
Release date:1999-07-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of core binding factor beta and map of the CBF alpha binding site.
Nat.Struct.Biol., 6, 1999
1MRV
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CRYSTAL STRUCTURE OF AN INACTIVE AKT2 KINASE DOMAIN
Descriptor:RAC-beta serine/threonine kinase
Authors:Huang, X., Begley, M., Morgenstern, K.A., Gu, Y., Rose, P., Zhao, H., Zhu, X.
Deposit date:2002-09-18
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of an inactive akt2 kinase domain
Structure, 11, 2003
1MRY
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CRYSTAL STRUCTURE OF AN INACTIVE AKT2 KINASE DOMAIN
Descriptor:RAC-beta serine/threonine kinase
Authors:Huang, X., Begley, M., Morgenstern, K.A., Gu, Y., Rose, P., Zhao, H., Zhu, X.
Deposit date:2002-09-18
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of an inactive akt2 kinase domain
Structure, 11, 2003
4HGS
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CRYSTAL STRUCTURE OF CK1GS WITH COMPOUND 13
Descriptor:Casein kinase I isoform gamma-3, 2-{2-[(3,4-difluorophenoxy)methyl]-5-methoxypyridin-4-yl}-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one
Authors:Huang, X.
Deposit date:2012-10-08
Release date:2012-11-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of ck1gs with compound 13
Acs Med.Chem.Lett
6IP1
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ALPHA-SNAP-SNARE SUBCOMPLEX IN THE WHOLE 20S COMPLEX
Descriptor:Vesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25, ...
Authors:Huang, X., Sun, S., Wang, X., Fan, F., Zhou, Q., Sui, S.F.
Deposit date:2018-11-01
Release date:2019-04-24
Last modified:2019-05-01
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanistic insights into the SNARE complex disassembly.
Sci Adv, 5, 2019
6IP2
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NSF-D1D2 PART IN THE WHOLE 20S COMPLEX
Descriptor:Vesicle-fusing ATPase, ADENOSINE-5'-TRIPHOSPHATE
Authors:Huang, X., Sun, S., Wang, X., Fan, F., Zhou, Q., Sui, S.F.
Deposit date:2018-11-01
Release date:2019-04-24
Last modified:2019-05-01
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Mechanistic insights into the SNARE complex disassembly.
Sci Adv, 5, 2019
1EG3
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STRUCTURE OF A DYSTROPHIN WW DOMAIN FRAGMENT IN COMPLEX WITH A BETA-DYSTROGLYCAN PEPTIDE
Descriptor:DYSTROPHIN
Authors:Huang, X., Poy, F., Zhang, R., Joachimiak, A., Sudol, M., Eck, M.J.
Deposit date:2000-02-11
Release date:2000-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan.
Nat.Struct.Biol., 7, 2000
1EG4
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STRUCTURE OF A DYSTROPHIN WW DOMAIN FRAGMENT IN COMPLEX WITH A BETA-DYSTROGLYCAN PEPTIDE
Descriptor:BETA-DYSTROGLYCAN, DYSTROPHIN
Authors:Huang, X., Poy, F., Zhang, R., Joachimiak, A., Sudol, M., Eck, M.J.
Deposit date:2000-02-11
Release date:2000-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan.
Nat.Struct.Biol., 7, 2000
2JXW
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SOLUTION STRUCTURE OF THE TANDEM WW DOMAINS OF FBP21
Descriptor:WW domain-binding protein 4
Authors:Huang, X., Zhang, J., Wu, J., Shi, Y.
Deposit date:2007-11-30
Release date:2008-12-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21)
J.Biol.Chem., 284, 2009
2R8U
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STRUCTURE OF FRAGMENT OF HUMAN END-BINDING PROTEIN 1 (EB1) CONTAINING THE N-TERMINAL DOMAIN AT 1.35 A RESOLUTION
Descriptor:Microtubule-associated protein RP/EB family member 1, MOLYBDATE ION
Authors:Huang, X., Lovelace, L.L., Smith, D., Lebioda, L.
Deposit date:2007-09-11
Release date:2008-09-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution
To be Published
3EAW
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REPLACEMENT OF VAL3 IN HUMAN THYMIDYLATE SYNTHASE AFFECTS ITS KINETIC PROPERTIES AND INTRACELLULAR STABILITY
Descriptor:Thymidylate synthase, SULFATE ION, 1,2-ETHANEDIOL
Authors:Huang, X., Gibson, L.M., Bell, B.J., Lovelace, L.L., Pena, M.M., Berger, F.G., Berger, S.H.
Deposit date:2008-08-26
Release date:2010-03-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3EBU
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REPLACEMENT OF VAL3 IN HUMAN THYMIDYLATE SYNTHASE AFFECTS ITS KINETIC PROPERTIES AND INTRACELLULAR STABILITY
Descriptor:Thymidylate synthase, SULFATE ION, 1,2-ETHANEDIOL
Authors:Huang, X., Gibson, L.M., Bell, B.J., Lovelace, L.L., Pena, M.M., Berger, F.G., Berger, S.H.
Deposit date:2008-08-28
Release date:2010-03-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3ED7
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REPLACEMENT OF VAL3 IN HUMAN THYMIDYLATE SYNTHASE AFFECTS ITS KINETIC PROPERTIES AND INTRACELLULAR STABILITY
Descriptor:Thymidylate synthase, SULFATE ION
Authors:Huang, X., Gibson, L.M., Bell, B.J., Lovelace, L.L., Pena, M.M., Berger, F.G., Berger, S.H.
Deposit date:2008-09-02
Release date:2010-03-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3EDW
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REPLACEMENT OF VAL3 IN HUMAN THYMIDYLATE SYNTHASE AFFECTS ITS KINETIC PROPERTIES AND INTRACELLULAR STABILITY
Descriptor:Thymidylate synthase, SULFATE ION
Authors:Huang, X., Gibson, L.M., Bell, B.J., Lovelace, L.L., Pena, M.M., Berger, F.G., Berger, S.H.
Deposit date:2008-09-03
Release date:2010-03-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3EF9
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REPLACEMENT OF VAL3 IN HUMAN THYMIDYLATE SYNTHASE AFFECTS ITS KINETIC PROPERTIES AND INTRACELLULAR STABILITY
Descriptor:Thymidylate synthase, SULFATE ION
Authors:Huang, X., Gibson, L.M., Bell, B.J., Lovelace, L.L., Pena, M.M., Berger, F.G., Berger, S.H.
Deposit date:2008-09-08
Release date:2010-03-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3EJL
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REPLACEMENT OF VAL3 IN HUMAN THYMIDYLATE SYNTHASE AFFECTS ITS KINETIC PROPERTIES AND INTRACELLULAR STABILITY
Descriptor:Thymidylate synthase, PHOSPHATE ION, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE
Authors:Huang, X., Gibson, L.M., Bell, B.J., Lovelace, L.L., Pena, M.M., Berger, F.G., Berger, S.H.
Deposit date:2008-09-18
Release date:2010-03-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3GG5
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REPLACEMENT OF VAL3 IN HUMAN THYMIDYLATE SYNTHASE AFFECTS ITS KINETIC PROPERTIES AND INTRACELLULAR STABILITY
Descriptor:Thymidylate synthase, SULFATE ION, PHOSPHATE ION
Authors:Huang, X., Gibson, L.M., Bell, B.J., Lovelace, L.L., Lebioda, L.
Deposit date:2009-02-27
Release date:2010-03-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3GH0
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REPLACEMENT OF VAL3 IN HUMAN THYMIDYLATE SYNTHASE AFFECTS ITS KINETIC PROPERTIES AND INTRACELLULAR STABILITY
Descriptor:Thymidylate synthase, SULFATE ION
Authors:Huang, X., Gibson, L.M., Bell, B.J., Lovelace, L.L., Lebioda, L.
Deposit date:2009-03-02
Release date:2010-03-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3GH2
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REPLACEMENT OF VAL3 IN HUMAN THYMIDYLATE SYNTHASE AFFECTS ITS KINETIC PROPERTIES AND INTRACELLULAR STABILITY
Descriptor:Thymidylate synthase, SULFATE ION
Authors:Huang, X., Gibson, L.M., Bell, B.J., Lovelace, L.L., Lebioda, L.
Deposit date:2009-03-02
Release date:2010-03-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3O89
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CRYSTAL STRUCTURE OF SPERM WHALE MYOGLOBIN G65T
Descriptor:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Huang, X., Lovelace, L., Lebioda, L.
Deposit date:2010-08-02
Release date:2011-12-07
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Investigations of Structural Factors that Influence the Mechanism of Halophenol Dehalogenation using 'Peroxidase-Like' Myoglobin mutants and 'Myoglobin-Like' Amphitrite ornata Dehaloperoxidase Mutants
TO BE PUBLISHED
5Z4H
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BACTERIAL GYRB ATPASE DOMAIN IN COMPLEX WITH A CHEMICAL FRAGMENT
Descriptor:DNA gyrase subunit B, PHOSPHATE ION, 4-(4-hydroxyphenyl)sulfanylphenol, ...
Authors:Huang, X., Zhou, H.
Deposit date:2018-01-11
Release date:2018-12-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of an auxiliary druggable pocket in the DNA gyrase ATPase domain using fragment probes
Medchemcomm, 9, 2018
5Z4O
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BACTERIAL GYRB ATPASE DOMAIN IN COMPLEX WITH A CHEMICAL FRAGMENT
Descriptor:DNA gyrase subunit B, 4-phenoxyphenol, PHOSPHATE ION, ...
Authors:Huang, X., Zhou, H.
Deposit date:2018-01-12
Release date:2018-12-12
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Identification of an auxiliary druggable pocket in the DNA gyrase ATPase domain using fragment probes
Medchemcomm, 9, 2018
5Z9B
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BACTERIAL GYRB ATPASE DOMAIN IN COMPLEX WITH (3,4-DICHLOROPHENYL)HYDRAZINE
Descriptor:DNA gyrase subunit B, PHOSPHATE ION, (3,4-dichlorophenyl)hydrazine, ...
Authors:Huang, X., Zhou, H.
Deposit date:2018-02-02
Release date:2018-12-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of an auxiliary druggable pocket in the DNA gyrase ATPase domain using fragment probes
Medchemcomm, 9, 2018
5Z9E
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BACTERIAL GYRB ATPASE DOMAIN IN COMPLEX WITH A CHEMICAL FRAGMENT
Descriptor:DNA gyrase subunit B, PHOSPHATE ION, butyl 4-hydroxybenzoate, ...
Authors:Huang, X., Zhou, H.
Deposit date:2018-02-02
Release date:2018-12-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification of an auxiliary druggable pocket in the DNA gyrase ATPase domain using fragment probes
Medchemcomm, 9, 2018
5Z9F
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BACTERIAL GYRB ATPASE DOMAIN IN COMPLEX WITH A CHEMICAL FRAGMENT
Descriptor:DNA gyrase subunit B, PHOSPHATE ION, 2-hydroxybenzonitrile, ...
Authors:Huang, X., Zhou, H.
Deposit date:2018-02-03
Release date:2018-12-12
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Identification of an auxiliary druggable pocket in the DNA gyrase ATPase domain using fragment probes
Medchemcomm, 9, 2018