Author results

5EGC
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STRUCTURE OF THE ADENO-ASSOCIATED VIRUS SEROTYPE 1 SIALIC ACID COMPLEX
分子名称:Capsid protein, O-SIALIC ACID, MAGNESIUM ION
著者Huang, L.Y., Agbandje-McKenna, M.
登録日2015-10-27
公開日2016-03-23
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (3.011 Å)
主引用文献Characterization of the Adeno-Associated Virus 1 and 6 Sialic Acid Binding Site.
J.Virol., 90, 2016
5X8I
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CRYSTAL STRUCTURE OF HUMAN CLK1 IN COMPLEX WITH COMPOUND 25
分子名称:Dual specificity protein kinase CLK1, 5-[1-[(1S)-1-(4-fluorophenyl)ethyl]-[1,2,3]triazolo[4,5-c]quinolin-8-yl]-1,3-benzoxazole
著者Sun, Q.Z., Lin, G.F., Li, L.L., Jin, X.T., Huang, L.Y., Zhang, G., Wei, Y.Q., Lu, G.W., Yang, S.Y.
登録日2017-03-02
公開日2017-08-16
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Discovery of Potent and Selective Inhibitors of Cdc2-Like Kinase 1 (CLK1) as a New Class of Autophagy Inducers
J. Med. Chem., 60, 2017
6N48
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STRUCTURE OF BETA2 ADRENERGIC RECEPTOR BOUND TO BI167107, NANOBODY 6B9, AND A POSITIVE ALLOSTERIC MODULATOR
分子名称:Endolysin,Beta-2 adrenergic receptor,Beta-2 adrenergic receptor chimera, Camelid Antibody Fragment, 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, ...
著者Liu, X., Masoudi, A., Kahsai, A.W., Huang, L.Y., Pani, B., Hirata, K., Ahn, S., Lefkowitz, R.J., Kobilka, B.K.
登録日2018-11-17
公開日2019-06-26
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Mechanism of beta2AR regulation by an intracellular positive allosteric modulator.
Science, 364, 2019
6J3O
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CRYSTAL STRUCTURE OF THE HUMAN PCAF BROMODOMAIN IN COMPLEX WITH COMPOUND 12
分子名称:Histone acetyltransferase KAT2B, 3-methyl-2-[[(3~{R})-1-methylpiperidin-3-yl]amino]-5~{H}-pyrrolo[3,2-d]pyrimidin-4-one
著者Huang, L.Y., Li, H., Li, L.L., Niu, L., Seupel, R., Wu, C.Y., Li, G.B., Yu, Y.M., Brennan, P.E., Yang, S.Y.
登録日2019-01-05
公開日2019-05-01
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain.
J.Med.Chem., 62, 2019
6J3P
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CRYSTAL STRUCTURE OF THE HUMAN GCN5 BROMODOMAIN IN COMPLEX WITH COMPOUND (R,R)-36N
分子名称:Histone acetyltransferase KAT2A, 2-{[(3R,5R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methylpiperidin-3-yl]amino}-3-methyl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
著者Huang, L.Y., Li, H., Niu, L., Wu, C.Y., Yu, Y.M., Li, L.L., Yang, S.Y.
登録日2019-01-05
公開日2019-05-01
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain.
J.Med.Chem., 62, 2019
4JQI
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STRUCTURE OF ACTIVE BETA-ARRESTIN1 BOUND TO A G PROTEIN-COUPLED RECEPTOR PHOSPHOPEPTIDE
分子名称:Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ...
著者Shukla, A.K., Manglik, A., Kruse, A.C., Xiao, K., Reis, R.I., Tseng, W.C., Staus, D.P., Hilger, D., Uysal, S., Huang, L.H., Paduch, M., Shukla, P.T., Koide, A., Koide, S., Weis, W.I., Kossiakoff, A.A., Kobilka, B.K., Lefkowitz, R.J.
登録日2013-03-20
公開日2013-04-17
最終更新日2013-10-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
Nature, 497, 2013
5LY0
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CRYSTAL STRUCTURE OF LOB DOMAIN OF RAMOSA2 FROM WHEAT
分子名称:LOB family transfactor Ramosa2.1, ZINC ION
著者Wei, X.-B., Zhang, B., Chen, W.-F., Fan, S.-H., Rety, S., Xi, X.-G.
登録日2016-09-23
公開日2017-10-25
最終更新日2019-02-27
実験手法X-RAY DIFFRACTION (1.877 Å)
主引用文献Structural analysis reveals a "molecular calipers" mechanism for a LATERAL ORGAN BOUNDARIES DOMAIN transcription factor protein from wheat.
J. Biol. Chem., 294, 2019