Author results

4PFZ
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X-RAY CRYSTAL STRUCTURE OF 5-CARBOXYMETHYL-2-HYDROXYMUCONATE DELTA-ISOMERASE FROM MYCOBACTERIUM SMEGMATIS
Descriptor:5-carboxymethyl-2-hydroxymuconate delta-isomerase, SODIUM ION
Authors:Horanyi, P.S., Abendroth, J., Lorimer, D., Edwards, T., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-05-01
Release date:2014-11-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray Crystal Structure of 5-carboxymethyl-2-hydroxymuconate delta-isomerase from Mycobacterium smegmatis
To Be Published
4TMD
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X-RAY STRUCTURE OF PUTATIVE UNCHARACTERIZED PROTEIN (RV0999 ORTHOLOG) FROM MYCOBACTERIUM SMEGMATIS
Descriptor:Uncharacterized protein, IODIDE ION
Authors:Horanyi, P.S., Dranow, D.M., Abendroth, J., Lorimer, D., Edwards, T., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-06-01
Release date:2014-07-02
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of Putative uncharacterized protein (Rv0999 ortholog) from Mycobacterium smegmatis
To Be Published
4TWR
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STRUCTURE OF UDP-GLUCOSE 4-EPIMERASE FROM BRUCELLA ABORTUS
Descriptor:NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
Authors:Horanyi, P.S., Abendroth, J., Lorimer, D., Edwards, T., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-07-01
Release date:2014-10-08
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of UDP-glucose 4-epimerase from Brucella melitensis
To Be Published
6CAU
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UDP-N-ACETYLMURAMATE--ALANINE LIGASE FROM ACINETOBACTER BAUMANNII AB5075-UW WITH AMPPNP
Descriptor:UDP-N-acetylmuramate--L-alanine ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION
Authors:Horanyi, P.S., Abendroth, J., Lorimer, D.D., Edwards, T.E., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-01-31
Release date:2018-03-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:UDP-N-acetylmuramate--alanine ligase from Acinetobacter baumannii AB5075-UW with AMPPNP
To be Published
6CKG
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D-GLYCERATE 3-KINASE FROM CRYPTOCOCCUS NEOFORMANS VAR. GRUBII SEROTYPE A (H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
Descriptor:D-glycerate 3-kinase, 1,2-ETHANEDIOL
Authors:Horanyi, P.S., Abendroth, J., Lorimer, D.D., Edwards, T.E., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-02-28
Release date:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:D-glycerate 3-kinase from Cryptococcus neoformans var. grubii serotype A (H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
To be Published
3RGM
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CRYSTAL STRUCTURE OF SPIN-LABELED BTUB T156R1
Descriptor:Vitamin B12 transporter BtuB, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MAGNESIUM ION, ...
Authors:Horanyi, P.S., Freed, D.M., Wiener, M.C., Cafiso, D.S.
Deposit date:2011-04-08
Release date:2011-10-26
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Origin of Electron Paramagnetic Resonance Line Shapes on β-Barrel Membrane Proteins: The Local Solvation Environment Modulates Spin-Label Configuration
Biochemistry, 50, 2011
1UPS
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GLCNAC[ALPHA]1-4GAL RELEASING ENDO-[BETA]-GALACTOSIDASE FROM CLOSTRIDIUM PERFRINGENS
Descriptor:GLCNAC-ALPHA-1,4-GAL-RELEASING ENDO-BETA-GALACTOSIDASE, CALCIUM ION
Authors:Tempel, W., Liu, Z.-J., Horanyi, P.S., Deng, L., Lee, D., Newton, M.G., Rose, J.P., Ashida, H., Li, S.-C., Li, Y.-T., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-10-10
Release date:2004-11-25
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Three-dimensional structure of GlcNAcalpha1-4Gal releasing endo-beta-galactosidase from Clostridium perfringens.
Proteins, 59, 2005
1ZD0
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CRYSTAL STRUCTURE OF PFU-542154 CONSERVED HYPOTHETICAL PROTEIN
Descriptor:hypothetical protein PF0523, MAGNESIUM ION, UNKNOWN ATOM OR ION, ...
Authors:Habel, J.E., Liu, Z.J., Horanyi, P.S., Florence, Q.J.T., Tempel, W., Zhou, W., Chen, L., Lee, D., Nguyen, J., Chang, S.H., Bereton, P., Izumi, M., Jenny Jr., F.E., Poole II, F.L., Shah, C., Sugar, F.J., Adams, M.W.W., Rose, J.P., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-04-13
Release date:2005-05-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Pfu-542154 conserved hypothetical protein
To be Published
3M8B
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CRYSTAL STRUCTURE OF SPIN-LABELED BTUB V10R1 IN THE APO STATE
Descriptor:Vitamin B12 transporter btuB, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, ...
Authors:Freed, D.M., Horanyi, P.S., Wiener, M.C., Cafiso, D.S.
Deposit date:2010-03-17
Release date:2010-09-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Conformational exchange in a membrane transport protein is altered in protein crystals.
Biophys.J., 99, 2010
3M8D
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CRYSTAL STRUCTURE OF SPIN-LABELED BTUB V10R1 WITH BOUND CALCIUM AND CYANOCOBALAMIN
Descriptor:Vitamin B12 transporter btuB, CO-CYANOCOBALAMIN, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ...
Authors:Freed, D.M., Horanyi, P.S., Wiener, M.C., Cafiso, D.S.
Deposit date:2010-03-17
Release date:2010-09-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Conformational exchange in a membrane transport protein is altered in protein crystals.
Biophys.J., 99, 2010
3RGN
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CRYSTAL STRUCTURE OF SPIN-LABELED BTUB W371R1
Descriptor:Vitamin B12 transporter BtuB, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MAGNESIUM ION, ...
Authors:Freed, D.M., Horanyi, P.S., Wiener, M.C., Cafiso, D.S.
Deposit date:2011-04-08
Release date:2011-10-26
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Origin of Electron Paramagnetic Resonance Line Shapes on β-Barrel Membrane Proteins: The Local Solvation Environment Modulates Spin-Label Configuration
Biochemistry, 50, 2011
4IL3
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CRYSTAL STRUCTURE OF S. MIKATAE STE24P
Descriptor:Ste24p, ZINC ION
Authors:Pryor Jr., E.E., Horanyi, P.S., Clark, K., Fedoriw, N., Connelly, S.M., Koszelak-Rosenblum, M., Zhu, G., Malkowski, M.G., Dumont, M.E., Wiener, M.C., Membrane Protein Structural Biology Consortium (MPSBC)
Deposit date:2012-12-28
Release date:2013-02-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:Structure of the integral membrane protein CAAX protease Ste24p.
Science, 339, 2013
4IRG
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UNINHIBITED DNA-BINDING DOMAIN OF THE ETS TRANSCRIPTION FACTOR ERG
Descriptor:Transcriptional regulator ERG
Authors:Regan, M.C., Horanyi, P.S., Pryor, E.E., Sarver, J.L., Cafiso, D.S., Bushweller, J.H.
Deposit date:2013-01-14
Release date:2013-07-31
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IRH
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AUTO-INHIBITED ERG ETS DOMAIN
Descriptor:Transcriptional regulator ERG
Authors:Regan, M.C., Horanyi, P.S., Pryor, E.E., Sarver, J.L., Cafiso, D.S., Bushweller, J.H.
Deposit date:2013-01-14
Release date:2013-07-31
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IRI
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AUTO-INHIBITED ERG ETS DOMAIN-DNA COMPLEX
Descriptor:Transcriptional regulator ERG, DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*G)-3'), DNA (5'-D(*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3')
Authors:Regan, M.C., Horanyi, P.S., Pryor, E.E., Sarver, J.L., Cafiso, D.S., Bushweller, J.H.
Deposit date:2013-01-14
Release date:2013-07-31
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Proc.Natl.Acad.Sci.USA, 110, 2013
5UUI
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CRYSTAL STRUCTURE OF SPIN-LABELED T77C TNFA
Descriptor:Tumor necrosis factor, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Authors:Horanyi, P.S., Dranow, D.M., Ceska, T.
Deposit date:2017-02-16
Release date:2017-08-02
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Natural Conformational Sampling of Human TNF alpha Visualized by Double Electron-Electron Resonance.
Biophys. J., 113, 2017
4U7X
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CRYSTAL STRUCTURE OF FRUCTOKINASE FROM BRUCELLA ABORTUS 2308
Descriptor:Ribokinase:Carbohydrate kinase, PfkB, SODIUM ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-07-31
Release date:2014-09-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Fructokinase from Brucella abortus 2308
To Be Published
4WJM
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CRYSTAL STRUCTURE OF FRUCTOKINASE FROM BRUCELLA ABORTUS 2308 WITH BOUND AMPPNP
Descriptor:Ribokinase:Carbohydrate kinase, PfkB, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-10-01
Release date:2014-10-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Fructokinase from Brucella abortus 2308 with bound AMPPNP
To Be Published
5VVW
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STRUCTURE OF MURC FROM PSEUDOMONAS AERUGINOSA
Descriptor:UDP-N-acetylmuramate--L-alanine ligase, 1,2-ETHANEDIOL
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-05-21
Release date:2017-05-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of MurC from Pseudomonas aeruginosa
To Be Published
3MPN
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F177R1 MUTANT OF LEUT
Descriptor:Transporter, B-OCTYLGLUCOSIDE, LEUCINE, ...
Authors:Kroncke, B.M.
Deposit date:2010-04-27
Release date:2010-12-01
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural origins of nitroxide side chain dynamics on membrane protein alpha-helical sites.
Biochemistry, 49, 2010
3MPQ
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I204R1 MUTANT OF LEUT
Descriptor:Transporter, B-OCTYLGLUCOSIDE, LEUCINE, ...
Authors:Kroncke, B.M.
Deposit date:2010-04-27
Release date:2010-12-01
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural origins of nitroxide side chain dynamics on membrane protein alpha-helical sites.
Biochemistry, 49, 2010
4U83
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STRUCTURE OF BRUCELLA ABORTUS BUTYRYL-COA DEHYDROGENASE
Descriptor:Acyl-CoA dehydrogenase, 1,2-ETHANEDIOL
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-07-31
Release date:2014-12-17
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Butyryl-CoA dehydrogenase from Brucella Abortus.
To Be Published
4XGI
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CRYSTAL STRUCTURE OF GLUTAMATE DEHYDROGENASE FROM BURKHOLDERIA THAILANDENSIS
Descriptor:Glutamate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 2-OXOGLUTARIC ACID, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-12-30
Release date:2015-01-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Glutamate dehydrogenase from Burkholderia thailandensis
to be published
5CC8
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STRUCTURE OF THIAMINE-MONOPHOSPHATE KINASE FROM ACINETOBACTER BAUMANNII IN COMPLEX WITH AMPPNP
Descriptor:Thiamine-monophosphate kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-07-01
Release date:2015-09-02
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of thiamine monophosphate kinase from Acinetobacter baumannii in complex with substrates and products.
Sci Rep, 9, 2019
5CM7
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STRUCTURE OF THIAMINE-MONOPHOSPHATE KINASE FROM ACINETOBACTER BAUMANNII IN COMPLEX WITH ADENOSINE DIPHOSPHATE (ADP) AND THIAMINE DIPHOSPHATE (TPP)
Descriptor:Thiamine-monophosphate kinase, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-07-16
Release date:2015-08-26
Last modified:2019-03-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of thiamine monophosphate kinase from Acinetobacter baumannii in complex with substrates and products.
Sci Rep, 9, 2019