8UO8
Structure of synaptic vesicle protein 2B with padsevonil
This is a non-PDB format compatible entry.
Summary for 8UO8
Entry DOI | 10.2210/pdb8uo8/pdb |
EMDB information | 42430 |
Descriptor | Synaptic vesicle glycoprotein 2B, 2-acetamido-2-deoxy-beta-D-glucopyranose, (4R)-4-(2-chloro-2,2-difluoroethyl)-1-{[(4R)-2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl}pyrrolidin-2-one, ... (8 entities in total) |
Functional Keywords | synaptic vesicle, slc22, inhibitor, antiepileptic, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 81124.77 |
Authors | Martin, M.F.,Mittal, A.,Levin, E.,Adams, C.,Yang, M.,Ledecq, M.,Horyani, P.S.,Coleman, J.A. (deposition date: 2023-10-19, release date: 2024-05-22) |
Primary citation | Martin, M.F.,Coleman, J.A. Structure of synaptic vesicle protein 2B with padsevonil To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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