8UO8

Structure of synaptic vesicle protein 2B with padsevonil

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001669	cellular_component	acrosomal vesicle
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006836	biological_process	neurotransmitter transport
A	0007268	biological_process	chemical synaptic transmission
A	0008021	cellular_component	synaptic vesicle
A	0016020	cellular_component	membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0030672	cellular_component	synaptic vesicle membrane
A	0031410	cellular_component	cytoplasmic vesicle
A	0045202	cellular_component	synapse
A	0055085	biological_process	transmembrane transport
A	0099509	biological_process	regulation of presynaptic cytosolic calcium ion concentration
A	2000300	biological_process	regulation of synaptic vesicle exocytosis

Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	17
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. LGGLADKLGRKrvlsm.S

Chain	Residue	Details
A	LEU165-SER181

---

site_id	PS00217
Number of Residues	26
Details	SUGAR_TRANSPORT_2 Sugar transport proteins signature 2. IsGIGiGGalpivfaYfsEflsrekR

Chain	Residue	Details
A	ILE207-ARG232

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	240
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	168
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	52
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q8BG39","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---