Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
5MRU
DownloadVisualize
BU of 5mru by Molmil
TetR(class A) in complex with 5a,6-anhydrotetracycline and magnesium
Descriptor: 5A,6-ANHYDROTETRACYCLINE, MAGNESIUM ION, Tetracycline Repressor, ...
Authors:Hinrichs, W, Palm, G.J.
Deposit date:2016-12-26
Release date:2018-01-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:TetR(class A) in complex with 5a,6-anhydrotetracycline and magnesium
To Be Published
2TRT
DownloadVisualize
BU of 2trt by Molmil
TETRACYCLINE REPRESSOR CLASS D
Descriptor: MAGNESIUM ION, TETRACYCLINE, TETRACYCLINE REPRESSOR CLASS D
Authors:Hinrichs, W, Kisker, C, Saenger, W.
Deposit date:1994-03-04
Release date:1996-06-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance.
Science, 264, 1994
6YR2
DownloadVisualize
BU of 6yr2 by Molmil
TetR(D) soaked with Tigecycline P4(1)2(1)2
Descriptor: CHLORIDE ION, MAGNESIUM ION, SULFATE ION, ...
Authors:Hinrichs, W, Stary, K.
Deposit date:2020-04-19
Release date:2021-04-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:TetR(D) soaked with Tigecycline
to be published
6YR1
DownloadVisualize
BU of 6yr1 by Molmil
TetR(D) soaked with Tigecycline I4(1)22
Descriptor: CHLORIDE ION, MAGNESIUM ION, TIGECYCLINE, ...
Authors:Hinrichs, W, Stary, K.
Deposit date:2020-04-18
Release date:2021-04-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:TetR(D) soaked with Tigecycline
to be published
6FPM
DownloadVisualize
BU of 6fpm by Molmil
TetR(D) T103A mutant in complex with tetracycline and magnesium
Descriptor: CHLORIDE ION, MAGNESIUM ION, TETRACYCLINE, ...
Authors:Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
Deposit date:2018-02-11
Release date:2019-03-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
6FTS
DownloadVisualize
BU of 6fts by Molmil
TETR(D) N82A MUTANT IN COMPLEX WITH PEG4
Descriptor: CHLORIDE ION, TETRAETHYLENE GLYCOL, Tetracycline repressor protein class D
Authors:Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
Deposit date:2018-02-23
Release date:2019-02-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
6FPL
DownloadVisualize
BU of 6fpl by Molmil
TETR(D) E147A MUTANT IN COMPLEX WITH TETRACYCLINE AND MAGNESIUM
Descriptor: CHLORIDE ION, MAGNESIUM ION, TETRACYCLINE, ...
Authors:Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
Deposit date:2018-02-11
Release date:2019-03-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
2TCT
DownloadVisualize
BU of 2tct by Molmil
THE COMPLEX FORMED BETWEEN TET REPRESSOR AND TETRACYCLINE-MG2+ REVEALS MECHANISM OF ANTIBIOTIC RESISTANCE
Descriptor: 7-CHLOROTETRACYCLINE, MAGNESIUM ION, TETRACYCLINE REPRESSOR
Authors:Hinrichs, W, Kisker, C, Saenger, W.
Deposit date:1995-03-02
Release date:1996-04-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance.
J.Mol.Biol., 247, 1995
6QJW
DownloadVisualize
BU of 6qjw by Molmil
TetR(D) T103A mutant in complex with 7-chlortetracycline and magnesium
Descriptor: 7-CHLOROTETRACYCLINE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
Deposit date:2019-01-27
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
6RBM
DownloadVisualize
BU of 6rbm by Molmil
TETR(D) E147A MUTANT IN COMPLEX WITH MINOCYCLINE AND MAGNESIUM
Descriptor: (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
Deposit date:2019-04-11
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
6RCR
DownloadVisualize
BU of 6rcr by Molmil
TETR(D) H100A MUTANT IN COMPLEX WITH DOXYCYCLINE AND MAGNESIUM
Descriptor: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
Deposit date:2019-04-11
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
6RBL
DownloadVisualize
BU of 6rbl by Molmil
TETR(D) E147A MUTANT IN COMPLEX WITH DOXYCYCLINE AND MAGNESIUM
Descriptor: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
Deposit date:2019-04-10
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
6QJX
DownloadVisualize
BU of 6qjx by Molmil
TetR(D) T103A mutant in complex with minocycline and magnesium
Descriptor: (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
Deposit date:2019-01-27
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
6RGX
DownloadVisualize
BU of 6rgx by Molmil
TETR(D) N82A MUTANT IN COMPLEX WITH DOXYCYCLINE AND MAGNESIUM
Descriptor: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
Deposit date:2019-04-17
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
2XB5
DownloadVisualize
BU of 2xb5 by Molmil
Tet repressor (class D) in complex with 7-Iodotetracycline
Descriptor: 7-IODOTETRACYCLINE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Kisker, C, Saenger, W, Hinrichs, W.
Deposit date:2010-04-05
Release date:2010-10-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance.
Science, 264, 1994
8B7R
DownloadVisualize
BU of 8b7r by Molmil
Bacterial chalcone isomerase with taxifolin chalcone
Descriptor: (Z)-3-[3,4-bis(oxidanyl)phenyl]-2-oxidanyl-1-[2,4,6-tris(oxidanyl)phenyl]prop-2-en-1-one, CHLORIDE ION, Chalcone isomerase, ...
Authors:Hinrichs, W, Palm, G.J.
Deposit date:2022-10-02
Release date:2022-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Basis for (2 R ,3 R )-Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of Eubacterium ramulus .
Molecules, 27, 2022
8B7U
DownloadVisualize
BU of 8b7u by Molmil
Bacterial chalcone isomerase H33A with taxifolin
Descriptor: (2R,3R)-2-(3,4-DIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE, CHLORIDE ION, Chalcone isomerase, ...
Authors:Hinrichs, W, Palm, G.J.
Deposit date:2022-10-03
Release date:2022-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for (2 R ,3 R )-Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of Eubacterium ramulus .
Molecules, 27, 2022
1ORK
DownloadVisualize
BU of 1ork by Molmil
TET REPRESSOR, CLASS D IN COMPLEX WITH 9-(N,N-DIMETHYLGLYCYLAMIDO)-6-DEMETHYL-6-DEOXY-TETRACYCLINE
Descriptor: 9-(N,N-DIMETHYLGLYCYLAMIDO)-6-DEOXY-6-DEMETHYL-TETRACYCLINE, MAGNESIUM ION, TETRACYCLINE REPRESSOR
Authors:Orth, P, Schnappinger, D, Sum, P.-E, Ellestad, G.A, Hillen, W, Saenger, W, Hinrichs, W.
Deposit date:1998-05-21
Release date:1999-06-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline.
J.Mol.Biol., 285, 1999
8C77
DownloadVisualize
BU of 8c77 by Molmil
Human cathepsin L after reaction with the thiocarbazate inhibitor CID 16725315
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Cathepsin L, ...
Authors:Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A.
Deposit date:2023-01-12
Release date:2023-01-25
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors.
J.Med.Chem., 67, 2024
1QPI
DownloadVisualize
BU of 1qpi by Molmil
CRYSTAL STRUCTURE OF TETRACYCLINE REPRESSOR/OPERATOR COMPLEX
Descriptor: DNA (5'-D(*CP*CP*TP*AP*TP*CP*AP*AP*TP*GP*AP*TP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*TP*CP*AP*TP*TP*GP*AP*TP*AP*GP*G)-3'), IMIDAZOLE, ...
Authors:Orth, P, Schnappinger, D, Hillen, W, Saenger, W, Hinrichs, W.
Deposit date:1999-05-25
Release date:2000-02-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system.
Nat.Struct.Biol., 7, 2000
7PT0
DownloadVisualize
BU of 7pt0 by Molmil
SCO3201 with putative ligand
Descriptor: SPERMIDINE, TetR family transcriptional regulator
Authors:Werten, S, Palm, G.J, Hinrichs, W.
Deposit date:2021-09-25
Release date:2021-10-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal structures of free and ligand-bound forms of the TetR/AcrR-like regulator SCO3201 from Streptomyces coelicolor suggest a novel allosteric mechanism.
Febs J., 290, 2023
7OFU
DownloadVisualize
BU of 7ofu by Molmil
Structure of SARS-CoV-2 Papain-like protease PLpro in complex with 3, 4-Dihydroxybenzoic acid, methyl ester
Descriptor: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ...
Authors:Srinivasan, V, Ewert, W, Werner, N, Falke, S, Guenther, S, Reinke, P, Sprenger, J, Brognaro, H, Ullah, N, Andaleeb, H, Perbandt, M, Alves Franca, B, Schwinzer, M, Wang, M, Wolf, M, Lieske, J, Koua, F, Ginn, H, Lane, T.J, Yefanov, O, Gelisio, L, Hakanpaeae, J, Saouane, S, Tolstikova, A, Groessler, M, Fleckenstein, H, Trost, F, Lorenzen, K, Schubert, R, Han, H, Schmidt, C, Brings, L, Galchenkova, M, Gevorkov, Y, Li, C, Perk, A, Awel, S, Wahab, A, Choudary, I, Turk, D, Hinrichs, W, Chapman, H.N, Meents, A, Betzel, C.
Deposit date:2021-05-05
Release date:2021-05-12
Last modified:2024-09-18
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease.
Commun Biol, 5, 2022
7OFS
DownloadVisualize
BU of 7ofs by Molmil
Structure of SARS-CoV-2 Papain-like protease PLpro in complex with 4-(2-hydroxyethyl)phenol
Descriptor: 4-(2-hydroxyethyl)phenol, CHLORIDE ION, GLYCEROL, ...
Authors:Srinivasan, V, Werner, N, Falke, S, Guenther, S, Reinke, P, Ewert, W, Sprenger, J, Koua, F, Brognaro, H, Ullah, N, Andaleeb, H, Perbandt, M, Alves Franca, B, Schwinzer, M, Wang, M, Lieske, J, Ginn, H, Lane, T.J, Yefanov, O, Gelisio, L, Hakanpaeae, J, Saouane, S, Tolstikova, A, Groessler, M, Fleckenstein, H, Trost, F, Wolf, M, Lorenzen, K, Schubert, R, Han, H, Schmidt, C, Brings, L, Galchenkova, M, Gevorkov, Y, Li, C, Perk, A, Awel, S, Wahab, A, Choudary, I, Turk, D, Hinrichs, W, Chapman, H.N, Meents, A, Betzel, C.
Deposit date:2021-05-05
Release date:2021-05-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease.
Commun Biol, 5, 2022
7OFT
DownloadVisualize
BU of 7oft by Molmil
Structure of SARS-CoV-2 Papain-like protease PLpro in complex with p-hydroxybenzaldehyde
Descriptor: CHLORIDE ION, P-HYDROXYBENZALDEHYDE, POTASSIUM ION, ...
Authors:Srinivasan, V, Werner, N, Falke, S, Guenther, S, Reinke, P, Brognaro, H, Ullah, N, Andaleeb, H, Perbandt, M, Alves Franca, B, Schwinzer, M, Wang, M, Ewert, W, Sprenger, J, Lieske, J, Koua, F, Ginn, H, Lane, T.J, Wolf, M, Yefanov, O, Gelisio, L, Saouane, S, Tolstikova, A, Groessler, M, Fleckenstein, H, Trost, F, Lorenzen, K, Schubert, R, Han, H, Schmidt, C, Brings, L, Galchenkova, M, Gevorkov, Y, Li, C, Perk, A, Awel, S, Wahab, A, Choudary, I, Turk, D, Hinrichs, W, Chapman, H.N, Meents, A, Betzel, C.
Deposit date:2021-05-05
Release date:2021-05-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease.
Commun Biol, 5, 2022
2XPW
DownloadVisualize
BU of 2xpw by Molmil
TetR(D) in complex with oxytetracycline and magnesium.
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Dalm, D, Proft, J, Palm, G.J, Hinrichs, W.
Deposit date:2010-08-30
Release date:2011-09-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Tetr(D) in Complex with Oxytetracycline.
To be Published

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon