7OFU
Structure of SARS-CoV-2 Papain-like protease PLpro in complex with 3, 4-Dihydroxybenzoic acid, methyl ester
This is a non-PDB format compatible entry.
Summary for 7OFU
| Entry DOI | 10.2210/pdb7ofu/pdb |
| Descriptor | Papain-like protease nsp3, methyl 3,4-bis(oxidanyl)benzoate, GLYCEROL, ... (7 entities in total) |
| Functional Keywords | hydrolase papain-like protease plpro complex, hydrolase |
| Biological source | Severe acute respiratory syndrome coronavirus 2 |
| Total number of polymer chains | 1 |
| Total formula weight | 36504.58 |
| Authors | Srinivasan, V.,Ewert, W.,Werner, N.,Falke, S.,Guenther, S.,Reinke, P.,Sprenger, J.,Brognaro, H.,Ullah, N.,Andaleeb, H.,Perbandt, M.,Alves Franca, B.,Schwinzer, M.,Wang, M.,Wolf, M.,Lieske, J.,Koua, F.,Ginn, H.,Lane, T.J.,Yefanov, O.,Gelisio, L.,Hakanpaeae, J.,Saouane, S.,Tolstikova, A.,Groessler, M.,Fleckenstein, H.,Trost, F.,Lorenzen, K.,Schubert, R.,Han, H.,Schmidt, C.,Brings, L.,Galchenkova, M.,Gevorkov, Y.,Li, C.,Perk, A.,Awel, S.,Wahab, A.,Choudary, I.,Turk, D.,Hinrichs, W.,Chapman, H.N.,Meents, A.,Betzel, C. (deposition date: 2021-05-05, release date: 2021-05-12, Last modification date: 2024-01-31) |
| Primary citation | Srinivasan, V.,Brognaro, H.,Prabhu, P.R.,de Souza, E.E.,Gunther, S.,Reinke, P.Y.A.,Lane, T.J.,Ginn, H.,Han, H.,Ewert, W.,Sprenger, J.,Koua, F.H.M.,Falke, S.,Werner, N.,Andaleeb, H.,Ullah, N.,Franca, B.A.,Wang, M.,Barra, A.L.C.,Perbandt, M.,Schwinzer, M.,Schmidt, C.,Brings, L.,Lorenzen, K.,Schubert, R.,Machado, R.R.G.,Candido, E.D.,Oliveira, D.B.L.,Durigon, E.L.,Niebling, S.,Garcia, A.S.,Yefanov, O.,Lieske, J.,Gelisio, L.,Domaracky, M.,Middendorf, P.,Groessler, M.,Trost, F.,Galchenkova, M.,Mashhour, A.R.,Saouane, S.,Hakanpaa, J.,Wolf, M.,Alai, M.G.,Turk, D.,Pearson, A.R.,Chapman, H.N.,Hinrichs, W.,Wrenger, C.,Meents, A.,Betzel, C. Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease. Commun Biol, 5:805-805, 2022 Cited by PubMed: 35953531DOI: 10.1038/s42003-022-03737-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.72 Å) |
Structure validation
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