Author results

1P8J
  • Download 1p8j
  • View 1p8j
Molmil generated image of 1p8j
CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN
Descriptor:Furin precursor, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Henrich, S., Cameron, A., Bourenkov, G.P., Kiefersauer, R., Huber, R., Lindberg, I., Bode, W., Than, M.E.
Deposit date:2003-05-07
Release date:2003-07-08
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of the Proprotein Processing Proteinase Furin Explains its Stringent Specificity
Nat.Struct.Biol., 10, 2003
1LI1
  • Download 1li1
  • View 1li1
Molmil generated image of 1li1
THE 1.9-A CRYSTAL STRUCTURE OF THE NONCOLLAGENOUS (NC1) DOMAIN OF HUMAN PLACENTA COLLAGEN IV SHOWS STABILIZATION VIA A NOVEL TYPE OF COVALENT MET-LYS CROSS-LINK
Descriptor:Collagen alpha 1(IV), Collagen alpha 2(IV), ACETATE ION
Authors:Than, M.E., Henrich, S., Huber, R., Ries, A., Mann, K., Kuhn, K., Timpl, R., Bourenkov, G.P., Bartunik, H.D., Bode, W.
Deposit date:2002-04-17
Release date:2002-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link.
Proc.Natl.Acad.Sci.USA, 99, 2002
3N5E
  • Download 3n5e
  • View 3n5e
Molmil generated image of 3n5e
CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE BOUND TO A PEPTIDE INHIBITOR
Descriptor:Thymidylate synthase, Synthetic peptide LR, SULFATE ION
Authors:Pozzi, C., Cardinale, D., Guaitoli, G., Tondi, D., Luciani, R., Myllykallio, H., Ferrari, S., Costi, M.P., Mangani, S.
Deposit date:2010-05-25
Release date:2011-06-08
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 108, 2011
3N5G
  • Download 3n5g
  • View 3n5g
Molmil generated image of 3n5g
CRYSTAL STRUCTURE OF HISTIDINE-TAGGED HUMAN THYMIDYLATE SYNTHASE
Descriptor:Thymidylate synthase, SULFATE ION
Authors:Pozzi, C., Cardinale, D., Guaitoli, G., Tondi, D., Luciani, R., Myllykallio, H., Ferrari, S., Costi, M.P., Mangani, S.
Deposit date:2010-05-25
Release date:2011-06-08
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 108, 2011
5JCJ
  • Download 5jcj
  • View 5jcj
Molmil generated image of 5jcj
TRYPANOSOMA BRUCEI PTR1 IN COMPLEX WITH INHIBITOR NMT-H037 (COMPOUND 7)
Descriptor:Pteridine reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETATE ION, ...
Authors:Landi, G., Pozzi, C., Di Pisa, F., Dello Iacono, L., Mangani, S.
Deposit date:2016-04-15
Release date:2016-08-17
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.
J.Med.Chem., 59, 2016
5JCX
  • Download 5jcx
  • View 5jcx
Molmil generated image of 5jcx
TRYPANOSOMA BRUCEI PTR1 IN COMPLEX WITH INHIBITOR NP-29
Descriptor:Pteridine reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3,5,7-trihydroxy-2-(2-hydroxyphenyl)-4H-1-benzopyran-4-one, ...
Authors:Landi, G., Pozzi, C., Di Pisa, F., Dello Iacono, L., Mangani, S.
Deposit date:2016-04-15
Release date:2016-08-17
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.
J.Med.Chem., 59, 2016
5JDC
  • Download 5jdc
  • View 5jdc
Molmil generated image of 5jdc
TRYPANOSOMA BRUCEI PTR1 IN COMPLEX WITH INHIBITOR NP-13 (HESPERETIN)
Descriptor:Pteridine reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one, ...
Authors:Mangani, S., Pozzi, C., Di Pisa, F., Landi, G., Dello Iacono, L.
Deposit date:2016-04-16
Release date:2016-08-17
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.
J.Med.Chem., 59, 2016
5JDI
  • Download 5jdi
  • View 5jdi
Molmil generated image of 5jdi
TRYPANOSOMA BRUCEI PTR1 IN COMPLEX WITH COFACTOR AND INHIBITOR NMT-H024 (COMPOUND 2)
Descriptor:Pteridine reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETATE ION, ...
Authors:Landi, G., Pozzi, C., Di Pisa, F., Dello lacono, L., Mangani, S.
Deposit date:2016-04-16
Release date:2016-08-17
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.
J.Med.Chem., 59, 2016