Author results

1LQT
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A COVALENT MODIFICATION OF NADP+ REVEALED BY THE ATOMIC RESOLUTION STRUCTURE OF FPRA, A MYCOBACTERIUM TUBERCULOSIS OXIDOREDUCTASE
Descriptor:FprA, ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Bossi, R.T., Aliverti, A., Raimondi, D., Fischer, F., Zanetti, G., Ferrari, D., Tahallah, N., Maier, C.S., Heck, A.J.R., Rizzi, M., Mattevi, A., TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-05-13
Release date:2002-07-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase.
Biochemistry, 41, 2002
1LQU
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MYCOBACTERIUM TUBERCULOSIS FPRA IN COMPLEX WITH NADPH
Descriptor:FprA, ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Bossi, R.T., Aliverti, A., Raimondi, D., Fischer, F., Zanetti, G., Ferrari, D., Tahallah, N., Maier, C.S., Heck, A.J.R., Rizzi, M., Mattevi, A., TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-05-13
Release date:2002-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase.
Biochemistry, 41, 2002
3ZNH
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CRIMEAN CONGO HEMORRHAGIC FEVER VIRUS OTU DOMAIN IN COMPLEX WITH UBIQUITIN-PROPARGYL.
Descriptor:UBIQUITIN THIOESTERASE, POLYUBIQUITIN-B
Authors:Ekkebus, R., vanKasteren, S.I., Kulathu, Y., Scholten, A., Berlin, I., deJong, A., Goerdayal, G., Neefjes, J., Heck, A.J.R., Komander, D., Ovaa, H.
Deposit date:2013-02-14
Release date:2013-02-27
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:On Terminal Alkynes that Can React with Active-Site Cysteine Nucleophiles in Proteases.
J.Am.Chem.Soc., 135, 2013
4BBY
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MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: WILD-TYPE
Descriptor:ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Nenci, S., Piano, V., Rosati, S., Aliverti, A., Pandini, V., Fraaije, M.W., Heck, A.J.R., Edmondson, D.E., Mattevi, A.
Deposit date:2012-09-28
Release date:2012-11-07
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BC7
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MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: ARG419HIS MUTANT
Descriptor:ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Nenci, S., Piano, V., Rosati, S., Aliverti, A., Pandini, V., Fraaije, M.W., Heck, A.J.R., Edmondson, D.E., Mattevi, A.
Deposit date:2012-10-01
Release date:2012-11-07
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BC9
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MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: WILD-TYPE, ADDUCT WITH CYANOETHYL
Descriptor:ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, propanenitrile, ...
Authors:Nenci, S., Piano, V., Rosati, S., Aliverti, A., Pandini, V., Fraaije, M.W., Heck, A.J.R., Edmondson, D.E., Mattevi, A.
Deposit date:2012-10-01
Release date:2012-11-07
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BCA
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MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: TYR578PHE MUTANT
Descriptor:ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Nenci, S., Piano, V., Rosati, S., Aliverti, A., Pandini, V., Fraaije, M.W., Heck, A.J.R., Edmondson, D.E., Mattevi, A.
Deposit date:2012-10-01
Release date:2012-11-07
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
5NBT
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APO STRUCTURE OF P60N/P80C KATANIN
Descriptor:Katanin p80 WD40 repeat-containing subunit B1, Katanin p60 ATPase-containing subunit A1
Authors:Jiang, K., Rezabkova, L., Hua, S., Liu, Q., Capitani, G., Altelaar, A.F.M., Heck, A.J.R., Kammerer, R.A., Steinmetz, M.O., Akhmanova, A.
Deposit date:2017-03-02
Release date:2017-04-26
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.
Nat. Cell Biol., 19, 2017
5NMR
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MONOMERIC MOUSE SORTILIN EXTRACELLULAR DOMAIN
Descriptor:Sortilin, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION
Authors:Leloup, N.O.L., Loessl, P., Meijer, D.H.M., Heck, A.J.R., Thies-Weesie, D.M.E., Janssen, B.J.C.
Deposit date:2017-04-07
Release date:2017-12-06
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.
Nat Commun, 8, 2017
6QLD
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STRUCTURE OF INNER KINETOCHORE CCAN-CENP-A COMPLEX
Descriptor:Inner kinetochore subunit MIF2, DNA (125-MER), Inner kinetochore subunit MCM16, ...
Authors:Yan, K., Yang, J., Zhang, Z., McLaughlin, S.H., Chang, L., Fasci, D., Heck, A.J.R., Barford, D.
Deposit date:2019-01-31
Release date:2019-10-02
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (4.15 Å)
Cite:Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
6QLE
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STRUCTURE OF INNER KINETOCHORE CCAN COMPLEX
Descriptor:Central kinetochore subunit MCM16,Central kinetochore subunit MCM16,Inner kinetochore subunit MCM16,Mcm16p, Central kinetochore subunit CTF3,Inner kinetochore subunit CTF3,Central kinetochore subunit CTF3,Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM22,Inner kinetochore subunit MCM22,Inner kinetochore subunit MCM22,Inner kinetochore subunit MCM22, ...
Authors:Yan, K., Yang, J., Zhang, Z., McLaughlin, S.H., Chang, L., Fasci, D., Heck, A.J.R., Barford, D.
Deposit date:2019-01-31
Release date:2019-10-02
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
6QLF
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STRUCTURE OF INNER KINETOCHORE CCAN COMPLEX WITH MASK1
Descriptor:Inner kinetochore subunit IML3, Inner kinetochore subunit CHL4, Inner kinetochore subunit MCM21, ...
Authors:Yan, K., Yang, J., Zhang, Z., McLaughlin, S.H., Chang, L., Fasci, D., Heck, A.J.R., Barford, D.
Deposit date:2019-01-31
Release date:2019-10-02
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
3NFF
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CRYSTAL STRUCTURE OF EXTENDED DIMERIZATION MODULE OF RNA POLYMERASE I SUBCOMPLEX A49/A34.5
Descriptor:RNA polymerase I subunit A49, RNA polymerase I subunit A34.5
Authors:Geiger, S.R., Lorenzen, K., Schreieck, A., Hanecker, P., Kostrewa, D., Heck, A.J.R., Cramer, P.
Deposit date:2010-06-10
Release date:2010-09-08
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
3NFH
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CRYSTAL STRUCTURE OF TANDEM WINGED HELIX DOMAIN OF RNA POLYMERASE I SUBUNIT A49 (P4)
Descriptor:DNA-directed RNA polymerase I subunit RPA49
Authors:Geiger, S.R., Lorenzen, K., Schreieck, A., Hanecker, P., Kostrewa, D., Heck, A.J.R., Cramer, P.
Deposit date:2010-06-10
Release date:2010-09-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
3NFI
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CRYSTAL STRUCTURE OF TANDEM WINGED HELIX DOMAIN OF RNA POLYMERASE I SUBUNIT A49
Descriptor:DNA-directed RNA polymerase I subunit RPA49, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL
Authors:Geiger, S.R., Lorenzen, K., Schreieck, A., Hanecker, P., Kostrewa, D., Heck, A.J.R., Cramer, P.
Deposit date:2010-06-10
Release date:2010-09-08
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
3TJ1
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CRYSTAL STRUCTURE OF RNA POLYMERASE I TRANSCRIPTION INITIATION FACTOR RRN3
Descriptor:RNA polymerase I-specific transcription initiation factor RRN3
Authors:Blattner, C., Jennebach, S., Herzog, F., Mayer, A., Cheung, A.C.M., Witte, G., Lorenzen, K., Hopfner, K.-P., Heck, A.J.R., Aebersold, R., Cramer, P.
Deposit date:2011-08-23
Release date:2011-09-28
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth.
Genes Dev., 25, 2011
5HVZ
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CRYSTAL STRUCTURE OF SMAKAP AKB DOMAIN BOUND RIA DIMERIZATION/DOCKING (D/D) COMPLEX AT 2.0 A RESOLUTION
Descriptor:cAMP-dependent protein kinase type I-alpha regulatory subunit, Small membrane A-kinase anchor protein
Authors:Wu, J., Burgers, P.P., Bruystens, J., Heck, A.J.R., Taylor, S.S.
Deposit date:2016-01-28
Release date:2016-04-20
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of smAKAP and its regulation by PKA-mediated phosphorylation.
Febs J., 283, 2016
5N8Y
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KAICBA CIRCADIAN CLOCK BACKBONE MODEL BASED ON A CRYO-EM DENSITY
Descriptor:Circadian clock protein kinase KaiC, Circadian clock protein KaiB, Circadian clock protein KaiA
Authors:Schuller, J.M., Snijder, J., Loessl, P., Heck, A.J.R., Foerster, F.
Deposit date:2017-02-24
Release date:2017-03-29
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structures of the cyanobacterial circadian oscillator frozen in a fully assembled state.
Science, 355, 2017
3T8X
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CRYSTAL STRUCTURE OF HUMAN CD1B IN COMPLEX WITH SYNTHETIC ANTIGENIC DIACYLSULFOGLYCOLIPID SGL12 AND ENDOGENOUS SPACER
Descriptor:T-cell surface glycoprotein CD1b, Beta-2-microglobulin, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Garcia-Alles, L.F., Maveyraud, L., Mourey, L., Julien, S.
Deposit date:2011-08-02
Release date:2011-10-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural reorganization of the human CD1b Antigen-binding groove for presentation of mycobacterial sulfoglycolipids
To be Published
5HYM
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3-HYDROXYBENZOATE 6-HYDROXYLASE FROM RHODOCOCCUS JOSTII IN COMPLEX WITH PHOSPHATIDYLINOSITOL
Descriptor:Probable salicylate monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, Phosphatidylinositol, ...
Authors:Orru, R., Montersino, S., Mattevi, A., van Berkel, W.J.H.
Deposit date:2016-02-01
Release date:2017-02-01
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor.
Front Microbiol, 8, 2017
5LB7
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COMPLEX STRUCTURE BETWEEN P60N/P80C KATANIN AND A PEPTIDE DERIVED FROM ASPM
Descriptor:Katanin p80 WD40 repeat-containing subunit B1, Katanin p60 ATPase-containing subunit A1, Abnormal spindle-like microcephaly-associated protein homolog
Authors:Rezabkova, L., Capitani, G., Kammerer, R.A., Steinmetz, M.O.
Deposit date:2016-06-15
Release date:2017-04-26
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.
Nat. Cell Biol., 19, 2017
5NMT
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DIMER STRUCTURE OF SORTILIN ECTODOMAIN CRYSTAL FORM 1, 2.3A
Descriptor:Sortilin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Leloup, N.O.L., Janssen, B.J.C.
Deposit date:2017-04-07
Release date:2017-11-29
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.
Nat Commun, 8, 2017
5NNI
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DIMER STRUCTURE OF SORTILIN ECTODOMAIN CRYSTAL FORM 2, 3.2 ANGSTROM
Descriptor:Sortilin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Leloup, N.O.L., Janssen, B.J.C.
Deposit date:2017-04-09
Release date:2017-11-29
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.
Nat Commun, 8, 2017
5NNJ
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DIMER STRUCTURE OF SORTILIN ECTODOMAIN CRYSTAL FORM 3, 4.0 ANGSTROM
Descriptor:Sortilin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Leloup, N.O.L., Janssen, B.J.C.
Deposit date:2017-04-09
Release date:2017-11-29
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (4 Å)
Cite:Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.
Nat Commun, 8, 2017
6F3T
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CRYSTAL STRUCTURE OF THE HUMAN TAF5-TAF6-TAF9 COMPLEX
Descriptor:Transcription initiation factor TFIID subunit 5, Transcription initiation factor TFIID subunit 6, Transcription initiation factor TFIID subunit 9, ...
Authors:Haffke, M., Berger, I.
Deposit date:2017-11-28
Release date:2018-12-05
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly.
Nat. Struct. Mol. Biol., 25, 2018