Author results

1LQT
  • Download 1lqt
  • View 1lqt
Molmil generated image of 1lqt
A COVALENT MODIFICATION OF NADP+ REVEALED BY THE ATOMIC RESOLUTION STRUCTURE OF FPRA, A MYCOBACTERIUM TUBERCULOSIS OXIDOREDUCTASE
Descriptor:FprA, ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Bossi, R.T., Aliverti, A., Raimondi, D., Fischer, F., Zanetti, G., Ferrari, D., Tahallah, N., Maier, C.S., Heck, A.J.R., Rizzi, M., Mattevi, A., TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-05-13
Release date:2002-07-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase.
Biochemistry, 41, 2002
1LQU
  • Download 1lqu
  • View 1lqu
Molmil generated image of 1lqu
MYCOBACTERIUM TUBERCULOSIS FPRA IN COMPLEX WITH NADPH
Descriptor:FprA, ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Bossi, R.T., Aliverti, A., Raimondi, D., Fischer, F., Zanetti, G., Ferrari, D., Tahallah, N., Maier, C.S., Heck, A.J.R., Rizzi, M., Mattevi, A., TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-05-13
Release date:2002-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase.
Biochemistry, 41, 2002
3ZNH
  • Download 3znh
  • View 3znh
Molmil generated image of 3znh
CRIMEAN CONGO HEMORRHAGIC FEVER VIRUS OTU DOMAIN IN COMPLEX WITH UBIQUITIN-PROPARGYL.
Descriptor:UBIQUITIN THIOESTERASE, POLYUBIQUITIN-B
Authors:Ekkebus, R., vanKasteren, S.I., Kulathu, Y., Scholten, A., Berlin, I., deJong, A., Goerdayal, G., Neefjes, J., Heck, A.J.R., Komander, D., Ovaa, H.
Deposit date:2013-02-14
Release date:2013-02-27
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:On Terminal Alkynes that Can React with Active-Site Cysteine Nucleophiles in Proteases.
J.Am.Chem.Soc., 135, 2013
4BBY
  • Download 4bby
  • View 4bby
Molmil generated image of 4bby
MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: WILD-TYPE
Descriptor:ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Nenci, S., Piano, V., Rosati, S., Aliverti, A., Pandini, V., Fraaije, M.W., Heck, A.J.R., Edmondson, D.E., Mattevi, A.
Deposit date:2012-09-28
Release date:2012-11-07
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BC7
  • Download 4bc7
  • View 4bc7
Molmil generated image of 4bc7
MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: ARG419HIS MUTANT
Descriptor:ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Nenci, S., Piano, V., Rosati, S., Aliverti, A., Pandini, V., Fraaije, M.W., Heck, A.J.R., Edmondson, D.E., Mattevi, A.
Deposit date:2012-10-01
Release date:2012-11-07
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BC9
  • Download 4bc9
  • View 4bc9
Molmil generated image of 4bc9
MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: WILD-TYPE, ADDUCT WITH CYANOETHYL
Descriptor:ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, propanenitrile, ...
Authors:Nenci, S., Piano, V., Rosati, S., Aliverti, A., Pandini, V., Fraaije, M.W., Heck, A.J.R., Edmondson, D.E., Mattevi, A.
Deposit date:2012-10-01
Release date:2012-11-07
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BCA
  • Download 4bca
  • View 4bca
Molmil generated image of 4bca
MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: TYR578PHE MUTANT
Descriptor:ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Nenci, S., Piano, V., Rosati, S., Aliverti, A., Pandini, V., Fraaije, M.W., Heck, A.J.R., Edmondson, D.E., Mattevi, A.
Deposit date:2012-10-01
Release date:2012-11-07
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
5NBT
  • Download 5nbt
  • View 5nbt
Molmil generated image of 5nbt
APO STRUCTURE OF P60N/P80C KATANIN
Descriptor:Katanin p80 WD40 repeat-containing subunit B1, Katanin p60 ATPase-containing subunit A1
Authors:Jiang, K., Rezabkova, L., Hua, S., Liu, Q., Capitani, G., Altelaar, A.F.M., Heck, A.J.R., Kammerer, R.A., Steinmetz, M.O., Akhmanova, A.
Deposit date:2017-03-02
Release date:2017-04-26
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.
Nat. Cell Biol., 19, 2017
5NMR
  • Download 5nmr
  • View 5nmr
Molmil generated image of 5nmr
MONOMERIC MOUSE SORTILIN EXTRACELLULAR DOMAIN
Descriptor:Sortilin, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION
Authors:Leloup, N.O.L., Loessl, P., Meijer, D.H.M., Heck, A.J.R., Thies-Weesie, D.M.E., Janssen, B.J.C.
Deposit date:2017-04-07
Release date:2017-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.
Nat Commun, 8, 2017
3NFF
  • Download 3nff
  • View 3nff
Molmil generated image of 3nff
CRYSTAL STRUCTURE OF EXTENDED DIMERIZATION MODULE OF RNA POLYMERASE I SUBCOMPLEX A49/A34.5
Descriptor:RNA polymerase I subunit A49, RNA polymerase I subunit A34.5
Authors:Geiger, S.R., Lorenzen, K., Schreieck, A., Hanecker, P., Kostrewa, D., Heck, A.J.R., Cramer, P.
Deposit date:2010-06-10
Release date:2010-09-08
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
3NFH
  • Download 3nfh
  • View 3nfh
Molmil generated image of 3nfh
CRYSTAL STRUCTURE OF TANDEM WINGED HELIX DOMAIN OF RNA POLYMERASE I SUBUNIT A49 (P4)
Descriptor:DNA-directed RNA polymerase I subunit RPA49
Authors:Geiger, S.R., Lorenzen, K., Schreieck, A., Hanecker, P., Kostrewa, D., Heck, A.J.R., Cramer, P.
Deposit date:2010-06-10
Release date:2010-09-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
3NFI
  • Download 3nfi
  • View 3nfi
Molmil generated image of 3nfi
CRYSTAL STRUCTURE OF TANDEM WINGED HELIX DOMAIN OF RNA POLYMERASE I SUBUNIT A49
Descriptor:DNA-directed RNA polymerase I subunit RPA49, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL
Authors:Geiger, S.R., Lorenzen, K., Schreieck, A., Hanecker, P., Kostrewa, D., Heck, A.J.R., Cramer, P.
Deposit date:2010-06-10
Release date:2010-09-08
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
3TJ1
  • Download 3tj1
  • View 3tj1
Molmil generated image of 3tj1
CRYSTAL STRUCTURE OF RNA POLYMERASE I TRANSCRIPTION INITIATION FACTOR RRN3
Descriptor:RNA polymerase I-specific transcription initiation factor RRN3
Authors:Blattner, C., Jennebach, S., Herzog, F., Mayer, A., Cheung, A.C.M., Witte, G., Lorenzen, K., Hopfner, K.-P., Heck, A.J.R., Aebersold, R., Cramer, P.
Deposit date:2011-08-23
Release date:2011-09-28
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth.
Genes Dev., 25, 2011
5HVZ
  • Download 5hvz
  • View 5hvz
Molmil generated image of 5hvz
CRYSTAL STRUCTURE OF SMAKAP AKB DOMAIN BOUND RIA DIMERIZATION/DOCKING (D/D) COMPLEX AT 2.0 A RESOLUTION
Descriptor:cAMP-dependent protein kinase type I-alpha regulatory subunit, Small membrane A-kinase anchor protein
Authors:Wu, J., Burgers, P.P., Bruystens, J., Heck, A.J.R., Taylor, S.S.
Deposit date:2016-01-28
Release date:2016-04-20
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of smAKAP and its regulation by PKA-mediated phosphorylation.
Febs J., 283, 2016
5N8Y
  • Download 5n8y
  • View 5n8y
Molmil generated image of 5n8y
KAICBA CIRCADIAN CLOCK BACKBONE MODEL BASED ON A CRYO-EM DENSITY
Descriptor:Circadian clock protein kinase KaiC, Circadian clock protein KaiB, Circadian clock protein KaiA
Authors:Schuller, J.M., Snijder, J., Loessl, P., Heck, A.J.R., Foerster, F.
Deposit date:2017-02-24
Release date:2017-03-29
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structures of the cyanobacterial circadian oscillator frozen in a fully assembled state.
Science, 355, 2017
3T8X
  • Download 3t8x
  • View 3t8x
Molmil generated image of 3t8x
CRYSTAL STRUCTURE OF HUMAN CD1B IN COMPLEX WITH SYNTHETIC ANTIGENIC DIACYLSULFOGLYCOLIPID SGL12 AND ENDOGENOUS SPACER
Descriptor:T-cell surface glycoprotein CD1b, Beta-2-microglobulin, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Garcia-Alles, L.F., Maveyraud, L., Mourey, L., Julien, S.
Deposit date:2011-08-02
Release date:2011-10-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural reorganization of the human CD1b Antigen-binding groove for presentation of mycobacterial sulfoglycolipids
To be Published
5HYM
  • Download 5hym
  • View 5hym
Molmil generated image of 5hym
3-HYDROXYBENZOATE 6-HYDROXYLASE FROM RHODOCOCCUS JOSTII IN COMPLEX WITH PHOSPHATIDYLINOSITOL
Descriptor:Probable salicylate monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, Phosphatidylinositol, ...
Authors:Orru, R., Montersino, S., Mattevi, A., van Berkel, W.J.H.
Deposit date:2016-02-01
Release date:2017-02-01
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor.
Front Microbiol, 8, 2017
5LB7
  • Download 5lb7
  • View 5lb7
Molmil generated image of 5lb7
COMPLEX STRUCTURE BETWEEN P60N/P80C KATANIN AND A PEPTIDE DERIVED FROM ASPM
Descriptor:Katanin p80 WD40 repeat-containing subunit B1, Katanin p60 ATPase-containing subunit A1, Abnormal spindle-like microcephaly-associated protein homolog
Authors:Rezabkova, L., Capitani, G., Kammerer, R.A., Steinmetz, M.O.
Deposit date:2016-06-15
Release date:2017-04-26
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.
Nat. Cell Biol., 19, 2017
5NMT
  • Download 5nmt
  • View 5nmt
Molmil generated image of 5nmt
DIMER STRUCTURE OF SORTILIN ECTODOMAIN CRYSTAL FORM 1, 2.3A
Descriptor:Sortilin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Leloup, N.O.L., Janssen, B.J.C.
Deposit date:2017-04-07
Release date:2017-11-29
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.
Nat Commun, 8, 2017
5NNI
  • Download 5nni
  • View 5nni
Molmil generated image of 5nni
DIMER STRUCTURE OF SORTILIN ECTODOMAIN CRYSTAL FORM 2, 3.2 ANGSTROM
Descriptor:Sortilin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Leloup, N.O.L., Janssen, B.J.C.
Deposit date:2017-04-09
Release date:2017-11-29
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.
Nat Commun, 8, 2017
5NNJ
  • Download 5nnj
  • View 5nnj
Molmil generated image of 5nnj
DIMER STRUCTURE OF SORTILIN ECTODOMAIN CRYSTAL FORM 3, 4.0 ANGSTROM
Descriptor:Sortilin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Leloup, N.O.L., Janssen, B.J.C.
Deposit date:2017-04-09
Release date:2017-11-29
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (4 Å)
Cite:Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.
Nat Commun, 8, 2017
6F3T
  • Download 6f3t
  • View 6f3t
Molmil generated image of 6f3t
CRYSTAL STRUCTURE OF THE HUMAN TAF5-TAF6-TAF9 COMPLEX
Descriptor:Transcription initiation factor TFIID subunit 5, Transcription initiation factor TFIID subunit 6, Transcription initiation factor TFIID subunit 9, ...
Authors:Haffke, M., Berger, I.
Deposit date:2017-11-28
Release date:2018-12-05
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly.
Nat. Struct. Mol. Biol., 25, 2018