Author results

5XJ3
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COMPLEX STRUCTURE OF IPILIMUMAB-SCFV AND CTLA-4
Descriptor:ipilimumab-VH, ipilimumab-VL, Cytotoxic T-lymphocyte protein 4
Authors:He, M., Chai, Y., Qi, J., Tong, Z., Tan, S., Gao, G.F.
Deposit date:2017-04-29
Release date:2018-04-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies
Oncotarget, 8, 2017
4KUD
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CRYSTAL STRUCTURE OF N-TERMINAL ACETYLATED SIR3 BAH DOMAIN D205N MUTANT IN COMPLEX WITH YEAST NUCLEOSOME CORE PARTICLE
Descriptor:Histone H3, Histone H4, Histone H2A.2, ...
Authors:Yang, D., Fang, Q., Wang, M., Ren, R., Wang, H., He, M., Sun, Y., Yang, N., Xu, R.M.
Deposit date:2013-05-22
Release date:2013-08-07
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain
Nat.Struct.Mol.Biol., 2013
4KUI
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CRYSTAL STRUCTURE OF N-TERMINAL ACETYLATED YEAST SIR3 BAH DOMAIN
Descriptor:Regulatory protein SIR3, ISOPROPYL ALCOHOL, ACETIC ACID
Authors:Yang, D., Fang, Q., Wang, M., Ren, R., Wang, H., He, M., Sun, Y., Yang, N., Xu, R.M.
Deposit date:2013-05-22
Release date:2013-08-07
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain
Nat.Struct.Mol.Biol., 2013
4KUL
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CRYSTAL STRUCTURE OF N-TERMINAL ACETYLATED YEAST SIR3 BAH DOMAIN V83P MUTANT
Descriptor:Regulatory protein SIR3
Authors:Yang, D., Fang, Q., Wang, M., Ren, R., Wang, H., He, M., Sun, Y., Yang, N., Xu, R.M.
Deposit date:2013-05-22
Release date:2013-08-07
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain
Nat.Struct.Mol.Biol., 2013
1KLL
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MOLECULAR BASIS OF MITOMYCIN C RESICTANCE IN STREPTOMYCES: CRYSTAL STRUCTURES OF THE MRD PROTEIN WITH AND WITHOUT A DRUG DERIVATIVE
Descriptor:mitomycin-binding protein, 1,2-CIS-1-HYDROXY-2,7-DIAMINO-MITOSENE
Authors:Martin, T.W., Dauter, Z., Devedjiev, Y., Sheffield, P., Jelen, F., He, M., Sherman, D., Otlewski, J., Derewenda, Z.S., Derewenda, U.
Deposit date:2001-12-12
Release date:2002-07-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein.
Structure, 10, 2002
1KMZ
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MOLECULAR BASIS OF MITOMYCIN C RESICTANCE IN STREPTOMYCES: CRYSTAL STRUCTURES OF THE MRD PROTEIN WITH AND WITHOUT A DRUG DERIVATIVE
Descriptor:mitomycin-binding protein
Authors:Martin, T.W., Dauter, Z., Devedjiev, Y., Sheffield, P., Jelen, F., He, M., Sherman, D., Otlewski, J., Derewenda, Z.S., Derewenda, U.
Deposit date:2001-12-17
Release date:2002-07-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein.
Structure, 10, 2002
3B96
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STRUCTURAL BASIS FOR SUBSTRATE FATTY-ACYL CHAIN SPECIFICITY: CRYSTAL STRUCTURE OF HUMAN VERY-LONG-CHAIN ACYL-COA DEHYDROGENASE
Descriptor:Very long-chain specific acyl-CoA dehydrogenase, TETRADECANOYL-COA, FLAVIN-ADENINE DINUCLEOTIDE
Authors:McAndrew, R.P., Wang, Y., Mohsen, A.W., He, M., Vockley, J., Kim, J.J.
Deposit date:2007-11-02
Release date:2008-02-12
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural basis for substrate fatty acyl chain specificity: crystal structure of human very-long-chain acyl-CoA dehydrogenase.
J.Biol.Chem., 283, 2008
3VZX
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CRYSTAL STRUCTURE OF PCRB FROM BACILLUS SUBTILIS SUBAP. SUBTILIS STR. 168
Descriptor:Heptaprenylglyceryl phosphate synthase, MAGNESIUM ION, CHLORIDE ION
Authors:Ren, F., Feng, X., Ko, T.P., Huang, C.H., Hu, Y., Chan, H.C., Liu, Y.L., Wang, K., Chen, C.C., Pang, X., He, M., Li, Y., Oldfield, E., Guo, R.T.
Deposit date:2012-10-17
Release date:2012-12-26
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus
Chembiochem, 14, 2013
3VZY
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CRYSTAL STRUCTURE OF PCRB COMPLEXED WITH G1P FROM BACILLUS SUBTILIS SUBAP. SUBTILIS STR. 168
Descriptor:Heptaprenylglyceryl phosphate synthase, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Ren, F., Feng, X., Ko, T.P., Huang, C.H., Hu, Y., Chan, H.C., Liu, Y.L., Wang, K., Chen, C.C., Pang, X., He, M., Li, Y., Oldfield, E., Guo, R.T.
Deposit date:2012-10-17
Release date:2012-12-26
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus
Chembiochem, 14, 2013
3VZZ
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CRYSTAL STRUCTURE OF PCRB COMPLEXED WITH FSPP FROM BACILLUS SUBTILIS SUBAP. SUBTILIS STR. 168
Descriptor:Heptaprenylglyceryl phosphate synthase, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Ren, F., Feng, X., Ko, T.P., Huang, C.H., Hu, Y., Chan, H.C., Liu, Y.L., Wang, K., Chen, C.C., Pang, X., He, M., Li, Y., Oldfield, E., Guo, R.T.
Deposit date:2012-10-17
Release date:2012-12-26
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus
Chembiochem, 14, 2013
3W00
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CRYSTAL STRUCTURE OF PCRB COMPLEXED WITH G1P AND FSPP FROM BACILLUS SUBTILIS SUBAP. SUBTILIS STR. 168
Descriptor:Heptaprenylglyceryl phosphate synthase, PHOSPHATE ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ...
Authors:Ren, F., Feng, X., Ko, T.P., Huang, C.H., Hu, Y., Chan, H.C., Liu, Y.L., Wang, K., Chen, C.C., Pang, X., He, M., Li, Y., Oldfield, E., Guo, R.T.
Deposit date:2012-10-17
Release date:2012-12-26
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus
Chembiochem, 14, 2013
3W01
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CRYSTAL STRUCTURE OF PCRB COMPLEXED WITH PEG FROM STAPHYLOCOCCUS AUREUS SUBSP. AUREUS MU3
Descriptor:Heptaprenylglyceryl phosphate synthase, TRIETHYLENE GLYCOL
Authors:Ren, F., Feng, X., Ko, T.P., Huang, C.H., Hu, Y., Chan, H.C., Liu, Y.L., Wang, K., Chen, C.C., Pang, X., He, M., Li, Y., Oldfield, E., Guo, R.T.
Deposit date:2012-10-17
Release date:2012-12-26
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus
Chembiochem, 14, 2013
3W02
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CRYSTAL STRUCTURE OF PCRB COMPLEXED WITH SO4 FROM STAPHYLOCOCCUS AUREUS SUBSP. AUREUS MU3
Descriptor:Heptaprenylglyceryl phosphate synthase, SULFATE ION
Authors:Ren, F., Feng, X., Ko, T.P., Huang, C.H., Hu, Y., Chan, H.C., Liu, Y.L., Wang, K., Chen, C.C., Pang, X., He, M., Li, Y., Oldfield, E., Guo, R.T.
Deposit date:2012-10-17
Release date:2012-12-26
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus
Chembiochem, 14, 2013
4L6R
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STRUCTURE OF THE CLASS B HUMAN GLUCAGON G PROTEIN COUPLED RECEPTOR
Descriptor:Soluble cytochrome b562 and Glucagon receptor chimera, DI(HYDROXYETHYL)ETHER
Authors:Siu, F.Y., He, M., de Graaf, C., Han, G.W., Yang, D., Zhang, Z., Zhou, C., Xu, Q., Wacker, D., Joseph, J.S., Liu, W., Lau, J., Cherezov, V., Katritch, V., Wang, M.W., Stevens, R.C., GPCR Network (GPCR)
Deposit date:2013-06-12
Release date:2013-07-24
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the human glucagon class B G-protein-coupled receptor.
Nature, 499, 2013
5XS4
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STRUCTURE OF COXSACKIEVIRUS A6 (CVA6) VIRUS A-PARTICLE
Descriptor:Genome polyprotein
Authors:Zheng, Q.B., He, M.Z., Xu, L.F., Yu, H., Li, S.W., Cheng, T.
Deposit date:2017-06-12
Release date:2017-09-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
Nat Commun, 8, 2017
5XS5
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STRUCTURE OF COXSACKIEVIRUS A6 (CVA6) VIRUS PROCAPSID PARTICLE
Descriptor:Genome polyprotein
Authors:Zheng, Q.B., He, M.Z., Xu, L.F., Yu, H., Cheng, T., Li, S.W.
Deposit date:2017-06-12
Release date:2017-09-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
Nat Commun, 8, 2017
5XS7
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STRUCTURE OF COXSACKIEVIRUS A6 (CVA6) VIRUS A-PARTICLE IN COMPLEX WITH THE NEUTRALIZING ANTIBODY FRAGMENT 1D5
Descriptor:Light chain of Fab 1D5, Heavy chain of Fab 1D5, Genome polyprotein
Authors:Zheng, Q.B., He, M.Z., Xu, L.F., Yu, H., Li, S.W., Cheng, T.
Deposit date:2017-06-12
Release date:2017-09-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
Nat Commun, 8, 2017
6AJ0
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THE STRUCTURE OF ENTEROVIRUS D68 MATURE VIRION
Descriptor:Viral protein 1, Virion protein 2, Capsid protein VP3, ...
Authors:Zheng, Q.B., Zhu, R., Xu, L.F., He, M.Z., Yan, X.D., Cheng, T., Li, S.W.
Deposit date:2018-08-25
Release date:2018-11-07
Last modified:2018-12-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
Nat Microbiol, 4, 2019
6AJ2
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THE STRUCTURE OF ICAM-5 TRIGGERED ENTEROVIRUS D68 VIRUS A-PARTICLE
Descriptor:Capsid protein VP1, Capsid protein VP2, Capsid protein VP3
Authors:Zheng, Q.B., Zhu, R., Xu, L.F., He, M.Z., Yan, X.D., Cheng, T., Li, S.W.
Deposit date:2018-08-26
Release date:2018-11-07
Last modified:2018-12-26
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
Nat Microbiol, 4, 2019
6AJ3
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THE STRUCTURE OF ENTEROVIRUS D68 PROCAPSID
Descriptor:Capsid protein VP1, Capsid protein VP2, Capsid protein VP3
Authors:Zheng, Q.B., Zhu, R., Xu, L.F., He, M.Z., Yan, X.D., Cheng, T., Li, S.W.
Deposit date:2018-08-26
Release date:2018-11-07
Last modified:2018-12-26
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
Nat Microbiol, 4, 2019
6AJ7
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THE STRUCTURE OF ENTEROVIRUS D68 MATURE VIRION IN COMPLEX WITH FAB 15C5
Descriptor:VL of Fab 15C5, VH of Fab 15C5, Capsid protein VP1, ...
Authors:Zheng, Q.B., Zhu, R., Xu, L.F., He, M.Z., Yan, X.D., Cheng, T., Li, S.W.
Deposit date:2018-08-27
Release date:2018-11-07
Last modified:2018-12-26
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
Nat Microbiol, 4, 2019
6AJ9
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THE STRUCTURE OF ENTEROVIRUS D68 MATURE VIRION IN COMPLEX WITH FAB 15C5 AND 11G1
Descriptor:VL of Fab 11G1, VH of Fab 11G1, VL of Fab 15C5, ...
Authors:Zheng, Q.B., Zhu, R., Xu, L.F., He, M.Z., Yan, X.D., Cheng, T., Li, S.W.
Deposit date:2018-08-27
Release date:2018-11-07
Last modified:2018-12-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
Nat Microbiol, 4, 2019
6IGC
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CRYSTAL STRUCTURE OF HPV58/33/52 CHIMERIC L1 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-11-21
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
6IGD
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CRYSTAL STRUCTURE OF HPV58/33 CHIMERIC L1 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-11-21
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
6IGE
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CRYSTAL STRUCTURE OF HUMAN PAPILLOMAVIRUS TYPE 33 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-12-05
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
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