6U8A | |
6U88 | |
6U86 | |
6U84 | |
6NZU | | STRUCTURE OF THE HUMAN FRATAXIN-BOUND IRON-SULFUR CLUSTER ASSEMBLY COMPLEX | | 分子名称: | Cysteine desulfurase, mitochondrial, LYR motif-containing protein 4, ... | | 著者 | Fox, N.G., Yu, X., Xidong, F., Alain, M., Joseph, N., Claire, S.D., Christine, B., Han, S., Yue, W.W. | | 登録日 | 2019-02-14 | | 公開日 | 2019-05-22 | | 最終更新日 | 2019-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism.
Nat Commun, 10, 2019
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6MPB | |
6MP6 | |
6MNY | |
6J0L | | CRYSTAL STRUCTURE OF INTRACELLULAR B30.2 DOMAIN OF BTN3A3 MUTANT IN COMPLEX WITH SULFATE ION | | 分子名称: | Butyrophilin subfamily 3 member A3, SULFATE ION | | 著者 | Yang, Y.Y., Liu, W.D., Cai, N.N., Chen, C.C., Guo, R.T., Zhang, Y.H. | | 登録日 | 2018-12-24 | | 公開日 | 2019-04-03 | | 最終更新日 | 2019-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
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6J0K | | CRYSTAL STRUCTURE OF INTRACELLULAR B30.2 DOMAIN OF BTN3A3 MUTANT IN COMPLEX WITH HMBPP | | 分子名称: | Butyrophilin subfamily 3 member A3, (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate | | 著者 | Yang, Y.Y., Liu, W.D., Cai, N.N., Chen, C.C., Guo, R.T., Zhang, Y.H. | | 登録日 | 2018-12-24 | | 公開日 | 2019-04-03 | | 最終更新日 | 2019-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
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6J0G | | CRYSTAL STRUCTURE OF INTRACELLULAR B30.2 DOMAIN OF BTN3A3 MUTANT IN COMPLEX WITH HMBPP | | 分子名称: | Butyrophilin subfamily 3 member A3, (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate | | 著者 | Yang, Y.Y., Liu, W.D., Cai, N.N., Chen, C.C., Guo, R.T., Zhang, Y.H. | | 登録日 | 2018-12-24 | | 公開日 | 2019-04-03 | | 最終更新日 | 2019-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
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6J06 | | CRYSTAL STRUCTURE OF INTRACELLULAR B30.2 DOMAIN OF BTN3A1 IN COMPLEX WITH HMBPP-08 | | 分子名称: | Butyrophilin subfamily 3 member A1, (2E)-3-(hydroxymethyl)-4-(4-methylphenyl)but-2-en-1-yl trihydrogen diphosphate, SULFATE ION, ... | | 著者 | Yang, Y.Y., Liu, W.D., Cai, N.N., Chen, C.C., Guo, R.T., Zhang, Y.H. | | 登録日 | 2018-12-21 | | 公開日 | 2019-04-03 | | 最終更新日 | 2019-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
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6ITA | | CRYSTAL STRUCTURE OF INTRACELLULAR B30.2 DOMAIN OF BTN3A1 MUTANT | | 分子名称: | Butyrophilin subfamily 3 member A1 | | 著者 | Yang, Y.Y., Liu, W.D., Cai, N.N., Chen, C.C., Guo, R.T., Zhang, Y.H. | | 登録日 | 2018-11-20 | | 公開日 | 2019-04-03 | | 最終更新日 | 2019-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
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6ISM | | CRYSTAL STRUCTURE OF INTRACELLULAR B30.2 DOMAIN OF BTN3A1 MUTANT | | 分子名称: | Butyrophilin subfamily 3 member A1 | | 著者 | Yang, Y.Y., Liu, W.D., Cai, N.N., Chen, C.C., Guo, R.T., Zhang, Y.H. | | 登録日 | 2018-11-16 | | 公開日 | 2019-04-03 | | 最終更新日 | 2019-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
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6IIV | | CRYSTAL STRUCTURE OF THE HUMAN THROMBOXANE A2 RECEPTOR BOUND TO DALTROBAN | | 分子名称: | Soluble cytochrome b562,Thromboxane A2 receptor,Rubredoxin,Thromboxane A2 receptor, 2-[4-[2-[(4-chlorophenyl)sulfonylamino]ethyl]phenyl]ethanoic acid, ZINC ION, ... | | 著者 | Fan, H., Zhao, Q., Wu, B. | | 登録日 | 2018-10-07 | | 公開日 | 2018-12-19 | | 最終更新日 | 2018-12-26 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for ligand recognition of the human thromboxane A2receptor.
Nat. Chem. Biol., 15, 2019
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6IIU | | CRYSTAL STRUCTURE OF THE HUMAN THROMBOXANE A2 RECEPTOR BOUND TO RAMATROBAN | | 分子名称: | Soluble cytochrome b562,Thromboxane A2 receptor,Rubredoxin,Thromboxane A2 receptor, 3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid, ZINC ION, ... | | 著者 | Fan, H., Zhao, Q., Wu, B. | | 登録日 | 2018-10-07 | | 公開日 | 2018-12-19 | | 最終更新日 | 2018-12-26 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for ligand recognition of the human thromboxane A2receptor.
Nat. Chem. Biol., 15, 2019
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6BY9 | | CRYSTAL STRUCTURE OF EHMT1 | | 分子名称: | Histone-lysine N-methyltransferase EHMT1, UNKNOWN ATOM OR ION | | 著者 | Dong, A., Wei, Y., Li, A., Tempel, W., Han, S., Sunnerhagen, M., Penn, L., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Tong, Y., Structural Genomics Consortium (SGC) | | 登録日 | 2017-12-20 | | 公開日 | 2018-01-31 | | 最終更新日 | 2018-10-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of EHMT1
to be published
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6BBV | | CRYSTAL STRUCTURE OF JAK2 IN COMPLEX WITH COMPOUND 25 | | 分子名称: | Tyrosine-protein kinase JAK2, N-{cis-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide | | 著者 | Han, S. | | 登録日 | 2017-10-19 | | 公開日 | 2018-01-17 | | 最終更新日 | 2018-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases.
J. Med. Chem., 61, 2018
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6BBU | | CRYSTAL STRUCTURE OF JAK1 IN COMPLEX WITH COMPOUND 25 | | 分子名称: | Tyrosine-protein kinase JAK1, N-{cis-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide | | 著者 | Han, S. | | 登録日 | 2017-10-19 | | 公開日 | 2018-01-17 | | 最終更新日 | 2018-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases.
J. Med. Chem., 61, 2018
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6B5V | | STRUCTURE OF TRPV5 IN COMPLEX WITH ECONAZOLE | | 分子名称: | Transient receptor potential cation channel subfamily V member 5, 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, CALCIUM ION | | 著者 | Hughes, T.E.T., Lodowski, D.T., Huynh, K.W., Yazici, A., del Rosario, J., Kapoor, A., Basak, S., Samanta, A., Chakrapani, S., Zhou, Z.H., Filizola, M., Rohacs, T., Han, S., Moiseenkova-Bell, V.Y. | | 登録日 | 2017-09-29 | | 公開日 | 2017-12-27 | | 最終更新日 | 2018-01-31 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
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6A9F | | CRYSTAL STRUCTURE OF A CYCLASE FROM FISCHERELLA SP. TAU IN COMPLEX WITH 4-(1H-INDOL-3-YL)BUTAN-2-ONE | | 分子名称: | aromatic prenyltransferase, MAGNESIUM ION, CALCIUM ION, ... | | 著者 | Hu, X.Y., Liu, W.D., Chen, C.C., Guo, R.T. | | 登録日 | 2018-07-13 | | 公開日 | 2018-12-19 | | 最終更新日 | 2018-12-26 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement
Angew. Chem. Int. Ed. Engl., 57, 2018
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6A99 | | CRYSTAL STRUCTURE OF A STIG CYCLASES FISC FROM FISCHERELLA SP. TAU IN COMPLEX WITH (3Z)-3-(1-METHYL-2-PYRROLIDINYLIDENE)-3H-INDOLE | | 分子名称: | aromatic prenyltransferase, (3~{Z})-3-(1-methylpyrrolidin-2-ylidene)indole, CALCIUM ION, ... | | 著者 | Hu, X.Y., Liu, W.D., Chen, C.C., Guo, R.T. | | 登録日 | 2018-07-12 | | 公開日 | 2018-12-19 | | 最終更新日 | 2018-12-26 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement
Angew. Chem. Int. Ed. Engl., 57, 2018
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6A98 | | CRYSTAL STRUCTURE OF A CYCLASE FROM FISCHERELLA SP. TAU | | 分子名称: | aromatic prenyltransferase, B-OCTYLGLUCOSIDE, CALCIUM ION, ... | | 著者 | Hu, X.Y., Liu, W.D., Chen, C.C., Guo, R.T. | | 登録日 | 2018-07-12 | | 公開日 | 2018-12-19 | | 最終更新日 | 2018-12-26 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement
Angew. Chem. Int. Ed. Engl., 57, 2018
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6A92 | | CRYSTAL STRUCTURE OF A CYCLASE FILC1 FROM FISCHERELLA SP. | | 分子名称: | acyclase, CALCIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Hu, X.Y., Liu, W.D., Chen, C.C., Guo, R.T. | | 登録日 | 2018-07-11 | | 公開日 | 2018-12-19 | | 最終更新日 | 2018-12-26 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement
Angew. Chem. Int. Ed. Engl., 57, 2018
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6A8X | | CRYSTAL STRUCTURE OF A APO FORM CYCLASE FROM FISCHERELLA SP. | | 分子名称: | aromatic prenyltransferase, CALCIUM ION | | 著者 | Hu, X.Y., Liu, W.D., Chen, C.C., Guo, R.T. | | 登録日 | 2018-07-11 | | 公開日 | 2018-12-19 | | 最終更新日 | 2018-12-26 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement
Angew. Chem. Int. Ed. Engl., 57, 2018
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