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2JKB
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE NANB IN COMPLEX WITH 2, 7-ANHYDRO-NEU5AC
Descriptor:SIALIDASE B, 2-ACETYLAMINO-7-(1,2-DIHYDROXY-ETHYL)-3-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCTANE-5-CARBOXYLIC ACID, 1,2-ETHANEDIOL
Authors:Gut, H., King, S.J., Walsh, M.A.
Deposit date:2008-08-26
Release date:2008-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural and Functional Studies of Streptococcus Pneumoniae Neuraminidase B: An Intramolecular Trans-Sialidase.
FEBS Lett., 582, 2008
2YA4
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE NANA (TIGR4)
Descriptor:NEURAMINIDASE A, FORMIC ACID, 1,2-ETHANEDIOL, ...
Authors:Gut, H., Xu, G., Taylor, G.L., Walsh, M.A.
Deposit date:2011-02-18
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Streptococcus Pneumoniae Nana Inhibition by Influenza Antivirals Zanamivir and Oseltamivir Carboxylate.
J.Mol.Biol., 409, 2011
2YA5
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE NANA (TIGR4) IN COMPLEX WITH SIALIC ACID
Descriptor:NEURAMINIDASE A, O-SIALIC ACID, FORMIC ACID, ...
Authors:Gut, H., Xu, G., Taylor, G.L., Walsh, M.A.
Deposit date:2011-02-18
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Streptococcus Pneumoniae Nana Inhibition by Influenza Antivirals Zanamivir and Oseltamivir Carboxylate.
J.Mol.Biol., 409, 2011
2YA6
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE NANA (TIGR4) IN COMPLEX WITH DANA
Descriptor:NEURAMINIDASE A, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, FORMIC ACID, ...
Authors:Gut, H., Xu, G., Taylor, G.L., Walsh, M.A.
Deposit date:2011-02-18
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Streptococcus Pneumoniae Nana Inhibition by Influenza Antivirals Zanamivir and Oseltamivir Carboxylate.
J.Mol.Biol., 409, 2011
2YA7
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE NANA (TIGR4) IN COMPLEX WITH ZANAMIVIR
Descriptor:NEURAMINIDASE A, ZANAMIVIR, CHLORIDE ION
Authors:Gut, H., Xu, G., Taylor, G.L., Walsh, M.A.
Deposit date:2011-02-18
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural Basis for Streptococcus Pneumoniae Nana Inhibition by Influenza Antivirals Zanamivir and Oseltamivir Carboxylate.
J.Mol.Biol., 409, 2011
2YA8
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE NANA (TIGR4) IN COMPLEX WITH OSELTAMIVIR CARBOXYLATE
Descriptor:NEURAMINIDASE A, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CHLORIDE ION, ...
Authors:Gut, H., Xu, G., Taylor, G.L., Walsh, M.A.
Deposit date:2011-02-18
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for Streptococcus Pneumoniae Nana Inhibition by Influenza Antivirals Zanamivir and Oseltamivir Carboxylate.
J.Mol.Biol., 409, 2011
3HBX
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CRYSTAL STRUCTURE OF GAD1 FROM ARABIDOPSIS THALIANA
Descriptor:Glutamate decarboxylase 1
Authors:Gut, H., Dominici, P., Pilati, S., Gruetter, M.G., Capitani, G.
Deposit date:2009-05-05
Release date:2009-07-28
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.672 Å)
Cite:A common structural basis for pH- and calmodulin-mediated regulation in plant glutamate decarboxylase.
J.Mol.Biol., 392, 2009
2DGK
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CRYSTAL STRUCTURE OF AN N-TERMINAL DELETION MUTANT OF ESCHERICHIA COLI GADB IN AN AUTOINHIBITED STATE (ALDAMINE)
Descriptor:Glutamate decarboxylase beta, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Gruetter, M.G., Capitani, G., Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
2DGL
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI GADB IN COMPLEX WITH BROMIDE
Descriptor:Glutamate decarboxylase beta, BROMIDE ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Gruetter, M.G., Capitani, G., Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
2DGM
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI GADB IN COMPLEX WITH IODIDE
Descriptor:Glutamate decarboxylase beta, IODIDE ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Gruetter, M.G., Capitani, G., Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
5FIR
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CRYSTAL STRUCTURE OF C. ELEGANS XRN2 IN COMPLEX WITH THE XRN2-BINDING DOMAIN OF PAXT-1
Descriptor:5'-3' EXORIBONUCLEASE 2 HOMOLOG, PAXT-1, SULFATE ION
Authors:Richter, H., Katic, I., Gut, H., Grosshans, H.
Deposit date:2015-10-02
Release date:2016-01-20
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (2.836 Å)
Cite:Structural Basis and Function of Xrn2-Binding by Xtb Domains
Nat.Struct.Mol.Biol., 23, 2016
2YB8
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CRYSTAL STRUCTURE OF NURF55 IN COMPLEX WITH SU(Z)12
Descriptor:POLYCOMB PROTEIN SU(Z)12, PROBABLE HISTONE-BINDING PROTEIN CAF1, SULFATE ION
Authors:Schmitges, F.W., Prusty, A.B., Faty, M., Stutzer, A., Lingaraju, G.M., Aiwazian, J., Sack, R., Hess, D., Li, L., Zhou, S., Bunker, R.D., Wirth, U., Bouwmeester, T., Bauer, A., Ly-Hartig, N., Zhao, K., Chan, H., Gu, J., Gut, H., Fischle, W., Muller, J., Thoma, N.H.
Deposit date:2011-03-02
Release date:2011-05-18
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks.
Mol.Cell, 42, 2011
2YBA
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CRYSTAL STRUCTURE OF NURF55 IN COMPLEX WITH HISTONE H3
Descriptor:PROBABLE HISTONE-BINDING PROTEIN CAF1, HISTONE H3
Authors:Schmitges, F.W., Prusty, A.B., Faty, M., Stutzer, A., Lingaraju, G.M., Aiwazian, J., Sack, R., Hess, D., Li, L., Zhou, S., Bunker, R.D., Wirth, U., Bouwmeester, T., Bauer, A., Ly-Hartig, N., Zhao, K., Chan, H., Gu, J., Gut, H., Fischle, W., Muller, J., Thoma, N.H.
Deposit date:2011-03-02
Release date:2011-05-11
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks
Mol.Cell, 42, 2011
6FPT
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CRYSTAL STRUCTURE OF DANIO RERIO LIN41 FILAMIN-NHL DOMAINS
Descriptor:E3 ubiquitin-protein ligase TRIM71
Authors:Kumari, P., Aeschimann, F., Gaidatzis, D., Keusch, J.J., Ghosh, P., Neagu, A., Pachulska-Wieczorek, K., Bujnicki, J.M., Gut, H., Grosshans, H., Ciosk, R.
Deposit date:2018-02-12
Release date:2018-05-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018
6FQ3
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CRYSTAL STRUCTURE OF DANIO RERIO LIN41 FILAMIN-NHL DOMAINS IN COMPLEX WITH LIN-29A 5'UTR 13MER RNA
Descriptor:E3 ubiquitin-protein ligase TRIM71, RNA (5'-R(*GP*GP*AP*GP*UP*CP*CP*AP*AP*CP*UP*CP*C)-3'), CHLORIDE ION
Authors:Kumari, P., Aeschimann, F., Gaidatzis, D., Keusch, J.J., Ghosh, P., Neagu, A., Pachulska-Wieczorek, K., Bujnicki, J.M., Gut, H., Grosshans, H., Ciosk, R.
Deposit date:2018-02-13
Release date:2018-05-09
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018
6FQL
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CRYSTAL STRUCTURE OF DANIO RERIO LIN41 FILAMIN-NHL DOMAINS IN COMPLEX WITH MAB-10 3'UTR 13MER RNA
Descriptor:E3 ubiquitin-protein ligase TRIM71, RNA (5'-R(*UP*GP*CP*AP*UP*UP*UP*AP*AP*UP*GP*CP*A)-3'), CHLORIDE ION
Authors:Kumari, P., Aeschimann, F., Gaidatzis, D., Keusch, J.J., Ghosh, P., Neagu, A., Pachulska-Wieczorek, K., Bujnicki, J.M., Gut, H., Grosshans, H., Ciosk, R.
Deposit date:2018-02-14
Release date:2018-05-09
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018
1M4N
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CRYSTAL STRUCTURE OF APPLE ACC SYNTHASE IN COMPLEX WITH [2-(AMINO-OXY)ETHYL](5'-DEOXYADENOSIN-5'-YL)(METHYL)SULFONIUM
Descriptor:1-aminocyclopropane-1-carboxylate synthase, PYRIDOXAL-5'-PHOSPHATE, (2-AMINOOXY-ETHYL)-[5-(6-AMINO-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDRO-FURAN-2-YLMETHYL]-METHYL-SULFONIUM, ...
Authors:Capitani, G., Eliot, A.C., Gut, H., Khomutov, R.M., Kirsch, J.F., Grutter, M.G.
Deposit date:2002-07-03
Release date:2003-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structure of 1-aminocyclopropane-1-carboxylate synthase in complex with an amino-oxy analogue of the substrate: implications for substrate binding.
BIOCHEM.BIOPHYS.ACTA PROTEINS & PROTEOMICS, 1647, 2003
1M7Y
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CRYSTAL STRUCTURE OF APPLE ACC SYNTHASE IN COMPLEX WITH L-AMINOETHOXYVINYLGLYCINE
Descriptor:1-aminocyclopropane-1-carboxylate synthase, (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, (4R)-2-METHYLPENTANE-2,4-DIOL
Authors:Capitani, G., McCarthy, D., Gut, H., Gruetter, M.G., Kirsch, J.F.
Deposit date:2002-07-23
Release date:2002-12-23
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Apple 1-Aminocyclopropane-1-carboxylate Synthase in Complex with the Inhibitor L-Aminoethoxyvinylglycine
J.Biol.Chem., 277, 2002
1PMM
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI GADB (LOW PH)
Descriptor:Glutamate decarboxylase beta, PYRIDOXAL-5'-PHOSPHATE, ACETIC ACID
Authors:Capitani, G., De Biase, D., Aurizi, C., Gut, H., Bossa, F., Grutter, M.G.
Deposit date:2003-06-11
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and functional analysis of escherichia coli glutamate decarboxylase
Embo J., 22, 2003
1PMO
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI GADB (NEUTRAL PH)
Descriptor:Glutamate decarboxylase beta, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Capitani, G., De Biase, D., Aurizi, C., Gut, H., Bossa, F., Grutter, M.G.
Deposit date:2003-06-11
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and functional analysis of escherichia coli glutamate decarboxylase
Embo J., 22, 2003
3ZCO
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CRYSTAL STRUCTURE OF S. CEREVISIAE SIR3 C-TERMINAL DOMAIN
Descriptor:REGULATORY PROTEIN SIR3
Authors:Oppikofer, M., Kueng, S., Keusch, J.J., Hassler, M., Ladurner, A.G., Gut, H., Gasser, S.M.
Deposit date:2012-11-21
Release date:2013-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Dimerization of Sir3 Via its C-Terminal Winged Helix Domain is Essential for Yeast Heterochromatin Formation.
Embo J., 32, 2013
4A08
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STRUCTURE OF HSDDB1-DRDDB2 BOUND TO A 13 BP CPD-DUPLEX (PURINE AT D-1 POSITION) AT 3.0 A RESOLUTION (CPD 1)
Descriptor:DNA DAMAGE-BINDING PROTEIN 1, DNA DAMAGE-BINDING PROTEIN 2, 5'-D(*AP*CP*GP*CP*GP*AP*(TTD)P*GP*CP*GP*CP*CP*C)-3', ...
Authors:Scrima, A., Fischer, E.S., Iwai, S., Gut, H., Thoma, N.H.
Deposit date:2011-09-08
Release date:2011-11-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation
Cell(Cambridge,Mass.), 147, 2011
4A09
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STRUCTURE OF HSDDB1-DRDDB2 BOUND TO A 15 BP CPD-DUPLEX (PURINE AT D-1 POSITION) AT 3.1 A RESOLUTION (CPD 2)
Descriptor:DNA DAMAGE-BINDING PROTEIN 1, DNA DAMAGE-BINDING PROTEIN 2, 5'-D(*GP*GP*TP*GP*AP*AP*AP*(TTD)P*AP*GP*CP*AP*GP*GP)-3', ...
Authors:Scrima, A., Fischer, E.S., Iwai, S., Gut, H., Thoma, N.H.
Deposit date:2011-09-08
Release date:2011-11-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation
Cell(Cambridge,Mass.), 147, 2011
4A0A
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STRUCTURE OF HSDDB1-DRDDB2 BOUND TO A 16 BP CPD-DUPLEX (PYRIMIDINE AT D-1 POSITION) AT 3.6 A RESOLUTION (CPD 3)
Descriptor:DNA DAMAGE-BINDING PROTEIN 1, DNA DAMAGE-BINDING PROTEIN 2, 5'-D(*GP*GP*TP*GP*AP*AP*AP*(TTD)P*AP*GP*CP*AP*GP*DGP)-3', ...
Authors:Scrima, A., Fischer, E.S., Iwai, S., Gut, H., Thoma, N.H.
Deposit date:2011-09-08
Release date:2011-11-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation
Cell(Cambridge,Mass.), 147, 2011
4A0B
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STRUCTURE OF HSDDB1-DRDDB2 BOUND TO A 16 BP CPD-DUPLEX (PYRIMIDINE AT D-1 POSITION) AT 3.8 A RESOLUTION (CPD 4)
Descriptor:DNA DAMAGE-BINDING PROTEIN 1, DNA DAMAGE-BINDING PROTEIN 2, 5'-D(*DGP*GP*TP*GP*AP*AP*AP*(TTD)P*AP*GP*CP*AP*GP*DGP)-3', ...
Authors:Scrima, A., Fischer, E.S., Iwai, S., Gut, H., Thoma, N.H.
Deposit date:2011-09-08
Release date:2011-11-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation
Cell(Cambridge,Mass.), 147, 2011
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