6FQ3

Crystal structure of Danio rerio Lin41 filamin-NHL domains in complex with lin-29A 5'UTR 13mer RNA

Summary for 6FQ3

Related6FPT
DescriptorE3 ubiquitin-protein ligase TRIM71, RNA (5'-R(*GP*GP*AP*GP*UP*CP*CP*AP*AP*CP*UP*CP*C)-3'), CHLORIDE ION, ... (4 entities in total)
Functional Keywordspost-transcriptional regulation, rna binding protein
Biological sourceDanio rerio (Zebrafish)
More
Cellular locationCytoplasm, P-body  E7FAM5
Total number of polymer chains2
Total molecular weight49024.96
Authors
Primary citation
Kumari, P.,Aeschimann, F.,Gaidatzis, D.,Keusch, J.J.,Ghosh, P.,Neagu, A.,Pachulska-Wieczorek, K.,Bujnicki, J.M.,Gut, H.,Grosshans, H.,Ciosk, R.
Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9:1549-1549, 2018
PubMed: 29674686 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-018-03920-7
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.901 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.181200.9%5.0%0.69MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution