Author results

2DGK
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CRYSTAL STRUCTURE OF AN N-TERMINAL DELETION MUTANT OF ESCHERICHIA COLI GADB IN AN AUTOINHIBITED STATE (ALDAMINE)
Descriptor:Glutamate decarboxylase beta, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Gruetter, M.G., Capitani, G., Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
2DGL
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI GADB IN COMPLEX WITH BROMIDE
Descriptor:Glutamate decarboxylase beta, BROMIDE ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Gruetter, M.G., Capitani, G., Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
2DGM
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI GADB IN COMPLEX WITH IODIDE
Descriptor:Glutamate decarboxylase beta, IODIDE ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Gruetter, M.G., Capitani, G., Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
2FBE
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CRYSTAL STRUCTURE OF THE PRYSPRY-DOMAIN
Descriptor:PREDICTED: similar to ret finger protein-like 1
Authors:Gruetter, C., Briand, C., Capitani, G., Mittl, P.R., Gruetter, M.G.
Deposit date:2005-12-09
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structure of the PRYSPRY-domain: Implications for autoinflammatory diseases
Febs Lett., 580, 2006
2I1B
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CRYSTALLOGRAPHIC REFINEMENT OF INTERLEUKIN-1 BETA AT 2.0 ANGSTROMS RESOLUTION
Descriptor:INTERLEUKIN-1 BETA
Authors:Priestle, J.P., Schaer, H.-P., Gruetter, M.G.
Deposit date:1990-01-02
Release date:1990-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic refinement of interleukin 1 beta at 2.0 A resolution.
Proc.Natl.Acad.Sci.USA, 86, 1989
2WL1
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PYRIN PRYSPRY DOMAIN
Descriptor:PYRIN, THIOCYANATE ION, 1,2-ETHANEDIOL
Authors:Weinert, C., Mittl, P.R., Gruetter, M.G.
Deposit date:2009-06-19
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The Crystal Structure of Human Pyrin B30.2 Domain: Implications for Mutations Associated with Familial Mediterranean Fever.
J.Mol.Biol., 394, 2009
1M7Y
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CRYSTAL STRUCTURE OF APPLE ACC SYNTHASE IN COMPLEX WITH L-AMINOETHOXYVINYLGLYCINE
Descriptor:1-aminocyclopropane-1-carboxylate synthase, (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, (4R)-2-METHYLPENTANE-2,4-DIOL
Authors:Capitani, G., McCarthy, D., Gut, H., Gruetter, M.G., Kirsch, J.F.
Deposit date:2002-07-23
Release date:2002-12-23
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Apple 1-Aminocyclopropane-1-carboxylate Synthase in Complex with the Inhibitor L-Aminoethoxyvinylglycine
J.Biol.Chem., 277, 2002
1MJ0
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SANK E3_5: AN ARTIFICIAL ANKYRIN REPEAT PROTEIN
Descriptor:SANK E3_5 Protein, SULFATE ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Kohl, A., Binz, H.K., Forrer, P., Stumpp, M.T., Plueckthun, A., Gruetter, M.G.
Deposit date:2002-08-26
Release date:2003-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.031 Å)
Cite:Designed to be stable: Crystal structure of a consensus ankyrin repeat protein
Proc.Natl.Acad.Sci.USA, 100, 2003
1SVX
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CRYSTAL STRUCTURE OF A DESIGNED SELECTED ANKYRIN REPEAT PROTEIN IN COMPLEX WITH THE MALTOSE BINDING PROTEIN
Descriptor:Ankyrin Repeat Protein off7, Maltose-binding periplasmic protein
Authors:Binz, H.K., Amstutz, P., Kohl, A., Stumpp, M.T., Briand, C., Forrer, P., Gruetter, M.G., Plueckthun, A.
Deposit date:2004-03-30
Release date:2004-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:High-affinity binders selected from designed ankyrin repeat protein libraries
NAT.BIOTECHNOL., 22, 2004
1VRS
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CRYSTAL STRUCTURE OF THE DISULFIDE-LINKED COMPLEX BETWEEN THE N-TERMINAL AND C-TERMINAL DOMAIN OF THE ELECTRON TRANSFER CATALYST DSBD
Descriptor:Thiol:disulfide interchange protein dsbD
Authors:Rozhkova, A., Stirnimann, C.U., Frei, P., Grauschopf, U., Brunisholz, R., Gruetter, M.G., Capitani, G., Glockshuber, R.
Deposit date:2005-06-17
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis and kinetics of inter- and intramolecular disulfide exchange in the redox catalyst DsbD
Embo J., 23, 2004
1Z5Y
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CRYSTAL STRUCTURE OF THE DISULFIDE-LINKED COMPLEX BETWEEN THE N-TERMINAL DOMAIN OF THE ELECTRON TRANSFER CATALYST DSBD AND THE CYTOCHROME C BIOGENESIS PROTEIN CCMG
Descriptor:Thiol:disulfide interchange protein dsbD, Thiol:disulfide interchange protein dsbE, CHLORIDE ION, ...
Authors:Stirnimann, C.U., Rozhkova, A., Grauschopf, U., Gruetter, M.G., Glockshuber, R., Capitani, G.
Deposit date:2005-03-21
Release date:2005-07-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural Basis and Kinetics of DsbD-Dependent Cytochrome c Maturation
STRUCTURE, 13, 2005
2FWE
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE ELECTRON TRANSFER CATALYST DSBD (OXIDIZED FORM)
Descriptor:Thiol:disulfide interchange protein dsbD, IODIDE ION, NICKEL (II) ION, ...
Authors:Stirnimann, C.U., Rozhkova, A., Grauschopf, U., Boeckmann, R.A., Glockshuber, R., Capitani, G., Gruetter, M.G.
Deposit date:2006-02-02
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:High-resolution structures of Escherichia coli cDsbD in different redox states: A combined crystallographic, biochemical and computational study
J.Mol.Biol., 358, 2006
2FWF
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HIGH RESOLUTION CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE ELECTRON TRANSFER CATALYST DSBD (REDUCED FORM)
Descriptor:Thiol:disulfide interchange protein dsbD, IODIDE ION, SODIUM ION
Authors:Stirnimann, C.U., Rozhkova, A., Grauschopf, U., Boeckmann, R.A., Glockshuber, R., Capitani, G., Gruetter, M.G.
Deposit date:2006-02-02
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:High-resolution structures of Escherichia coli cDsbD in different redox states: A combined crystallographic, biochemical and computational study
J.Mol.Biol., 358, 2006
2FWG
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HIGH RESOLUTION CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE ELECTRON TRANSFER CATALYST DSBD (PHOTOREDUCED FORM)
Descriptor:Thiol:disulfide interchange protein dsbD
Authors:Stirnimann, C.U., Rozhkova, A., Grauschopf, U., Boeckmann, R.A., Glockshuber, R., Capitani, G., Gruetter, M.G.
Deposit date:2006-02-02
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:High-resolution structures of Escherichia coli cDsbD in different redox states: A combined crystallographic, biochemical and computational study
J.Mol.Biol., 358, 2006
2FWH
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ATOMIC RESOLUTION CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE ELECTRON TRANSFER CATALYST DSBD (REDUCED FORM AT PH7)
Descriptor:Thiol:disulfide interchange protein dsbD, IODIDE ION, DI(HYDROXYETHYL)ETHER
Authors:Stirnimann, C.U., Rozhkova, A., Grauschopf, U., Boeckmann, R.A., Glockshuber, R., Capitani, G., Gruetter, M.G.
Deposit date:2006-02-02
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.99 Å)
Cite:High-resolution structures of Escherichia coli cDsbD in different redox states: A combined crystallographic, biochemical and computational study
J.Mol.Biol., 358, 2006
2RKO
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CRYSTAL STRUCTURE OF THE VPS4P-DIMER
Descriptor:Vacuolar protein sorting-associated protein 4
Authors:Hartmann, C., Gruetter, M.G.
Deposit date:2007-10-17
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Vacuolar protein sorting: two different functional states of the AAA-ATPase Vps4p
J.Mol.Biol., 377, 2008
2V50
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THE MISSING PART OF THE BACTERIAL MEXAB-OPRM SYSTEM: STRUCTURAL DETERMINATION OF THE MULTIDRUG EXPORTER MEXB
Descriptor:MULTIDRUG RESISTANCE PROTEIN MEXB, DODECYL-BETA-D-MALTOSIDE
Authors:Sennhauser, G., Bukowska, M.A., Gruetter, M.G.
Deposit date:2008-10-01
Release date:2009-05-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of the Multidrug Exporter Mexb from Pseudomonas Aeruginosa.
J.Mol.Biol., 389, 2009
2V7N
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UNUSUAL TWINNING IN CRYSTALS OF THE CITS BINDING ANTIBODY FAB FRAGMENT F3P4
Descriptor:IMMUNOGLOBULIN LIGHT CHAIN, IMMUNOGLOBULIN HEAVY CHAIN
Authors:Frey, D., Huber, T., Plueckthun, A., Gruetter, M.G.
Deposit date:2007-07-31
Release date:2008-06-17
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure of the Recombinant Antibody Fab Fragment F3P4.
Acta Crystallogr.,Sect.D, 64, 2008
3NDV
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CRYSTAL STRUCTURE OF THE N-TERMINAL BETA-AMINOPEPTIDASE BAPA IN COMPLEX WITH AMPICILLIN
Descriptor:Beta-peptidyl aminopeptidase, GLYCEROL, (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, ...
Authors:Merz, T., Heck, T., Geueke, B., Kohler, H.-P.E., Gruetter, M.G.
Deposit date:2010-06-08
Release date:2011-09-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures and inhibition of the beta-aminopeptidase BapA, a new ampicillin-recognizing member of the N-terminal nucleophile hydrolase family
To be Published
3NFB
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CRYSTAL STRUCTURE OF THE N-TERMINAL BETA-AMINOPEPTIDASE BAPA IN COMPLEX WITH HYDROLYZED AMPICILLIN
Descriptor:Beta-peptidyl aminopeptidase, GLYCEROL, (2S,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ...
Authors:Merz, T., Heck, T., Geueke, B., Kohler, H.-P.E., Gruetter, M.G.
Deposit date:2010-06-10
Release date:2011-09-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure and inhibition of the beta-aminopeptidase BapA, a new ampicillin-recognizing member of the N-terminal nucleophile hydrolase family
To be Published
4BS0
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CRYSTAL STRUCTURE OF KEMP ELIMINASE HG3.17 E47N,N300D COMPLEXED WITH TRANSITION STATE ANALOG 6-NITROBENZOTRIAZOLE
Descriptor:KEMP ELIMINASE HG3.17, SULFATE ION, 6-NITROBENZOTRIAZOLE
Authors:Blomberg, R., Kries, H., Pinkas, D.M., Mittl, P.R.E., Gruetter, M.G., Privett, H.K., Mayo, S., Hilvert, D.
Deposit date:2013-06-06
Release date:2013-10-16
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Precision is Essential for Efficient Catalysis in an Evolved Kemp Eliminase
Nature, 503, 2013
4CDL
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CRYSTAL STRUCTURE OF RETRO-ALDOLASE RA110.4-6 COMPLEXED WITH INHIBITOR 1-(6-METHOXY-2-NAPHTHALENYL)-1,3-BUTANEDIONE
Descriptor:STEROID DELTA-ISOMERASE, (2E)-1-(6-methoxynaphthalen-2-yl)but-2-en-1-one
Authors:Pinkas, D.M., Studer, S., Obexer, R., Giger, L., Gruetter, M.G., Baker, D., Hilvert, D.
Deposit date:2013-11-01
Release date:2014-11-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Active Site Plasticity of a Computationally Designed Retro-Aldolase Enzyme
To be Published
4CG4
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CRYSTAL STRUCTURE OF THE CHS-B30.2 DOMAINS OF TRIM20
Descriptor:PYRIN, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Weinert, C., Morger, D., Djekic, A., Mittl, P.R.E., Gruetter, M.G.
Deposit date:2013-11-20
Release date:2015-04-29
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Trim20 C-Terminal Coiled-Coil/B30.2 Fragment: Implications for the Recognition of Higher Order Oligomers
Sci.Rep., 5, 2015
1AIE
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P53 TETRAMERIZATION DOMAIN CRYSTAL STRUCTURE
Descriptor:P53
Authors:Mittl, P.R.E., Chene, P., Gruetter, M.G.
Deposit date:1997-04-17
Release date:1997-06-16
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystallization and structure solution of p53 (residues 326-356) by molecular replacement using an NMR model as template.
Acta Crystallogr.,Sect.D, 54, 1998
1TMT
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CHANGES IN INTERACTIONS IN COMPLEXES OF HIRUDIN DERIVATIVES AND HUMAN ALPHA-THROMBIN DUE TO DIFFERENT CRYSTAL FORMS
Descriptor:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), CGP 50,856 INHIBITOR, ...
Authors:Priestle, J.P., Gruetter, M.G.
Deposit date:1994-05-26
Release date:1994-09-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms.
Protein Sci., 2, 1993