3NFB

Crystal structure of the N-terminal beta-aminopeptidase BapA in complex with hydrolyzed ampicillin

Summary for 3NFB

• Entry DOI: 10.2210/pdb3nfb/pdb
• Related: 1B65 3N2W 3N33 3NDV
• Descriptor: Beta-peptidyl aminopeptidase, GLYCEROL, (2S,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ... (5 entities in total)
• Functional Keywords: ntn-hydrolase, alpha-beta-beta-alpha sandwich, beta-peptide cleaving enzyme, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Sphingosinicella xenopeptidilytica
• Total number of polymer chains: 4
• Total formula weight: 157496.49

Authors

Merz, T.,Heck, T.,Geueke, B.,Kohler, H.-P.E.,Gruetter, M.G. (deposition date: 2010-06-10, release date: 2011-09-28, Last modification date: 2023-09-06)

• Primary citation: Heck, T.,Merz, T.,Geueke, B.,Gruetter, M.G.,Kohler, H.-P.E.; Crystal structure and inhibition of the beta-aminopeptidase BapA, a new ampicillin-recognizing member of the N-terminal nucleophile hydrolase family; To be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)